Location · North Carolina
Clinical trials recruiting in North Carolina
857 recruiting studies have at least one site in North Carolina; 250 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in North Carolina.
857 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- Recruiting
Enhancing Heart Allograft Function With the OCS Heart System Trial
TransMedics
- Location
- Durham, NC + 6 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 4
Auryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone
Angiodynamics, Inc.
- Location
- Chapel Hill, NC + 8 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 1/Phase 2
A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)
Neurona Therapeutics
- Location
- Charlotte, NC + 15 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Undergoing Cardiac Surgery
Pacira Pharmaceuticals, Inc
- Location
- Durham, NC + 4 other US sites
- Eligibility basics
- Ages 0 mo–6
- RecruitingPhase 3
Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2
ReGenTree, LLC
- Location
- Durham, NC + 23 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 4
A Non-Randomized Open Label Clinical Trial Evaluating DermaBind TL
HealthTech Wound Care
- Location
- Cary, NC + 9 other US sites
- Eligibility basics
- Ages 18–80
- Recruiting
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR
Edwards Lifesciences
- Location
- Greensboro, NC + 49 other US sites
- Eligibility basics
- Ages 65+
- RecruitingPhase 2
A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)
Deciphera Pharmaceuticals, LLC
- Location
- Charlotte, NC + 25 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Knee Biofeedback Rehabilitation Through Game Therapy
Barron Associates, Inc.
- Location
- Chapel Hill, NC
- Eligibility basics
- Ages 30–75
- Recruiting
Comparative Study of Ziplyft Treatment vs. Traditional Blepharoplasty for Upper Eyelid Rejuvenation
Osheru Inc.
- Location
- Oxford, NC
- Eligibility basics
- Ages 35+
- RecruitingPhase 3
A Study to Assess the Safety and Effectiveness of ELAPR002f Injectable Gel in Adult Participants With Atrophic Acne Scars
AbbVie
- Location
- Wilmington, NC + 9 other US sites
- Eligibility basics
- Ages 22+
- RecruitingPhase 2
Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary Fibrosis
InSilico Medicine Hong Kong Limited
- Location
- Winston-Salem, NC + 11 other US sites
- Eligibility basics
- Ages 40+
- Recruiting
Long-Term Stability of the Glide Control Strategy
Infinite Biomedical Technologies
- Location
- Charlotte, NC + 9 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2
Mezzion Pharma Co. Ltd
- Location
- Durham, NC + 34 other US sites
- Eligibility basics
- Ages 12–18
- Recruiting
NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness
Endospan Ltd.
- Location
- Chapel Hill, NC + 23 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib
Kartos Therapeutics, Inc.
- Location
- Charleston, NC + 57 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 4
Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Extended-release Tablets in Pediatric Subjects Aged 5 to 17 Years With Active, Mild to Moderate Ulcerative Colitis
Bausch Health Americas, Inc.
- Location
- Greenville, NC + 3 other US sites
- Eligibility basics
- Ages 5–17
- RecruitingPhase 2
A Single Dose of BRTX 100 for Patients With Chronic Lumbar Disc Disease (cLDD)
BioRestorative Therapies
- Location
- Winston-Salem, NC + 13 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 4
A Study of CREXONT (Carbidopa and Levodopa) Extended-Release Capsules in Participants With Parkinson's Disease
Impax Laboratories, LLC
- Location
- Winston-Salem, NC + 22 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis
Sumitomo Pharma Switzerland GmbH
- Location
- Durham, NC + 101 other US sites
- Eligibility basics
- Ages 18–50 · Women only
- RecruitingPhase 3
Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults
SK Life Science, Inc.
- Location
- Durham, NC + 6 other US sites
- Eligibility basics
- Ages 4–55
- RecruitingPhase 2
Study of ALTO-300 in MDD
Alto Neuroscience
- Location
- Hickory, NC + 36 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 2
A Study to Evaluate the Safety and Efficacy of NEXAGON® (Lufepirsen Ophthalmic Gel) in Subjects With PCED
Glaukos Corporation
- Location
- Shelby, NC + 19 other US sites
- Eligibility basics
- Ages 2+
- RecruitingPhase 3
Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Esophagus
GIE Medical
- Location
- Chapel Hill, NC + 32 other US sites
- Eligibility basics
- Ages 22+