Location · North Carolina
Clinical trials recruiting in North Carolina
857 recruiting studies have at least one site in North Carolina; 250 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in North Carolina.
857 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Bowel
GIE Medical
- Location
- Chapel Hill, NC + 30 other US sites
- Eligibility basics
- Ages 22+
- RecruitingPhase 1
Study of APG-2575 as a Single Agent or in Combination With Other Therapeutic Agents for CLL/SLL
Ascentage Pharma Group Inc.
- Location
- Charlotte, NC + 6 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 3
A Phase III, Open Label, Randomized, Controlled Study of VBI-S in the Treatment of Hypovolemia in Patients With Septic Shock (VBI-S-02)
Vivacelle Bio
- Location
- Winston-Salem, NC + 4 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Phase 2a Proof of Concept Open-Label, Randomized, Controlled Study to Evaluate the Safety and Efficacy of MDI-1228-mesylate Gel Compared With Standard of Care Alone in Patients With Diabetic Foot Ulcers
Zhuhai Rui-Inno Pharmaceutical Technology Co., Ltd.
- Location
- Durham, NC
- Eligibility basics
- Ages 18–75
- Recruiting
Rising Tide - Amniotic Tissue(s) Treatments for Chronic Diabetic Foot Ulcers
Tides Medical
- Location
- Raleigh, NC + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 4
A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
Axsome Therapeutics, Inc.
- Location
- Hickory, NC + 36 other US sites
- Eligibility basics
- Ages 18–65
- Recruiting
EMAGINE 2.0 - Electromagnetic Field Ischemic Stroke - Novel Subacute Treatment
BrainQ Technologies Ltd.
- Location
- Charlotte, NC + 6 other US sites
- Eligibility basics
- Ages 22–80
- RecruitingPhase 2
A Study of NST-6179 in Subjects With Intestinal Failure-Associated Liver Disease (IFALD).
NorthSea Therapeutics B.V.
- Location
- Durham, NC + 11 other US sites
- Eligibility basics
- Ages 16+
- Recruiting
Multicenter Clinical Study of the SING-IMT in Patients with Late-stage AMD
VisionCare, Inc.
- Location
- Asheville, NC + 9 other US sites
- Eligibility basics
- Ages 65+
- RecruitingPhase 2
Treatment of Radiation and Cisplatin Induced Toxicities with Tempol
Matrix Biomed, Inc.
- Location
- Winston-Salem, NC + 7 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Assessment of the Initial Efficacy and Safety of BRM424 Ophthalmic Solutions in Patients With Neurotrophic Keratitis
BRIM Biotechnology Inc.
- Location
- Leland, NC
- Eligibility basics
- Ages 18+
- Recruiting
Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment
XSpline S.p.A.
- Location
- Durham, NC + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Preserved Ejection Fraction
Sardocor Corp.
- Location
- Durham, NC
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteers
Women s Health Awareness Community Resiliency, Environmental Action and Collaborations for Health (REACH)
National Institute of Environmental Health Sciences (NIEHS)
- Location
- Research Triangle Park, NC
- Eligibility basics
- Ages 18–100 · Women only
- RecruitingHealthy volunteers
Post-Operative Cesarean Section Cosmesis
Wake Forest University Health Sciences
- Location
- Winston-Salem, NC
- Eligibility basics
- Ages 18–44 · Women only
- RecruitingHealthy volunteers
Oxygen Toxicity: Mechanisms in Humans
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 18–45
- RecruitingHealthy volunteers
Intraoperative OCT Guidance of Intraocular Surgery II
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 1 mo+
- RecruitingHealthy volunteersPhase 3
Basal Cell Carcinoma Chemoprevention Trial
VA Office of Research and Development
- Location
- Durham, NC + 5 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 4
Enhancing PrEP Uptake and Retention Among Latine TGW and GBM in the South Using Long-Acting Injectable PrEP
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 18+ · Men only
- RecruitingHealthy volunteers
Study of the Effect of Innate on the Inflammatory Response to Endotoxin
National Institute of Environmental Health Sciences (NIEHS)
- Location
- Research Triangle Park, NC
- Eligibility basics
- Ages 18–100
- RecruitingHealthy volunteers
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others
Michael Shy
- Location
- Chapel Hill, NC + 17 other US sites
- Eligibility basics
- Any age listed
- RecruitingHealthy volunteers
Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2
University of Iowa
- Location
- Chapel Hill, NC + 17 other US sites
- Eligibility basics
- Any age listed
- RecruitingHealthy volunteers
Environmental Risk Factors for the Anti-synthetase Syndrome
National Institute of Environmental Health Sciences (NIEHS)
- Location
- Research Triangle Park, NC + 1 other US site
- Eligibility basics
- Ages 2–100
- RecruitingHealthy volunteers
Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network
National Human Genome Research Institute (NHGRI)
- Location
- Durham, NC + 23 other US sites
- Eligibility basics
- Ages 1 mo–100