Healthy volunteers · North Carolina
Studies for healthy volunteers in North Carolina
250 studies have at least one recruiting site in North Carolina. These studies say in their official record that they accept healthy volunteers. Many are Phase 1 studies that test how a new medicine is absorbed and tolerated; others recruit healthy people as a comparison group alongside patients.
250 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteers
Nutrition and Obesity in Under-Represented Populations: Food Insecurity Research to Advance Science and Improve Health
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 1–2
- RecruitingHealthy volunteers
Adolescent Mood During Puberty and Testosterone
University of North Carolina, Chapel Hill
- Location
- Chapel Hill, NC
- Eligibility basics
- Ages 11–14
- RecruitingHealthy volunteersPhase 3
Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial
University of Rochester
- Location
- Greensboro, NC + 43 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Maternal Autoimmune Disease Research Alliance (MADRA) Registry
Duke University
- Location
- Durham, NC
- Eligibility basics
- Any age listed · Women only
- RecruitingHealthy volunteers
Mobile Neurofeedback for Low Back Pain
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 18–90
- RecruitingHealthy volunteersPhase 4
Pilot Study of Fisetin to Improve Fatigue Among Older Adult Cancer Survivors
Wake Forest University Health Sciences
- Location
- Winston-Salem, NC
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteers
Virtual Village for Young Parents
RTI International
- Location
- Durham, NC
- Eligibility basics
- Ages 16–21
- RecruitingHealthy volunteers
Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)
Wake Forest University Health Sciences
- Location
- Winston-Salem, NC
- Eligibility basics
- Ages 7–18
- RecruitingHealthy volunteersPhase 4
Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 3–17
- RecruitingHealthy volunteers
BREAST Choice Decision Tool R21 - AIM2
UNC Lineberger Comprehensive Cancer Center
- Location
- Chapel Hill, NC
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Biomarker Development for Muscular Dystrophies
Massachusetts General Hospital
- Location
- Winston-Salem, NC + 3 other US sites
- Eligibility basics
- Ages 5+
- RecruitingHealthy volunteers
Supporting Health in Veterans With Heart Failure
Florida State University
- Location
- Durham, NC + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Evaluating the Status of Complex Aneuploidy to Locate Additional Transferrable Embryos
Shady Grove Fertility Reproductive Science Center
- Location
- Cary, NC + 9 other US sites
- Eligibility basics
- Any age listed
- RecruitingHealthy volunteers
Empowering Young Parents: Building Healthy Relationships Study
RTI International
- Location
- Sanford, NC + 6 other US sites
- Eligibility basics
- Ages 14–21 · Women only
- RecruitingHealthy volunteersPhase 4
Beta-Blocker Influences on Inflammatory and Neural Responses to Stress
University of North Carolina, Chapel Hill
- Location
- Chapel Hill, NC
- Eligibility basics
- Ages 18–30
- RecruitingHealthy volunteers
A Food As Medicine Approach to Address Food Insecurity in Rural North Carolina
North Carolina State University
- Location
- Raleigh, NC
- Eligibility basics
- Ages 8–64
- RecruitingHealthy volunteersPhase 3
Supraclavicular Bupivacaine Vs. Supraclavicular Liposomal Bupivacaine for Orthopedic Wrist Surgery
University of North Carolina, Chapel Hill
- Location
- Chapel Hill, NC
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Ultrasound for Quantifying Muscle Activation Elicited by Spinal Cord Stimulation and Functional Electrical Stimulation
North Carolina State University
- Location
- Raleigh, NC
- Eligibility basics
- Ages 18–60
- RecruitingHealthy volunteers
COA-APTIC Cognitive Interview Study of Caregiver and Clinician Assessment of Acute Pain in Infants and Young Children
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
SC2i Tissue and Data Repository Protocol
Henry M. Jackson Foundation for the Advancement of Military Medicine
- Location
- Durham, NC + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
A Novel Surgical Irrigation Solution in Post-Mastectomy Reconstruction: Evaluating Xperience™
University of North Carolina, Chapel Hill
- Location
- Chapel Hill, NC
- Eligibility basics
- Ages 18+ · Women only
- RecruitingHealthy volunteers
Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia
Massachusetts General Hospital
- Location
- Chapel Hill, NC + 19 other US sites
- Eligibility basics
- Ages 18–120
- RecruitingHealthy volunteers
Addressing Barriers to Achieving Cardiometabolic Disorders Prevention and Treatment Goals for PLWH in the SE US
Duke University
- Location
- Charlotte, NC + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
The VESPA Pilot Study
Wake Forest University
- Location
- Winston-Salem, NC
- Eligibility basics
- Ages 45–80
Who these studies look for
“Healthy” is decided at screening, not by you. Sites usually check vital signs, blood and urine tests, an ECG, your medications and sometimes your BMI or smoking status. A study can still turn you away for reasons that have nothing to do with being unwell, such as timing or a full roster.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do healthy volunteer studies pay?
Many do, because volunteers give up time and follow strict schedules, but amounts are set by each study and are usually only confirmed by the research site. When a record states an amount we show the exact wording; otherwise we say compensation is not disclosed.
What happens at a screening visit?
Expect consent paperwork first, then a health questionnaire, vital signs, blood and urine samples and often an ECG. You can ask questions and withdraw at any time, before or after you sign.