Healthy volunteers · North Carolina
Studies for healthy volunteers in North Carolina
250 studies have at least one recruiting site in North Carolina. These studies say in their official record that they accept healthy volunteers. Many are Phase 1 studies that test how a new medicine is absorbed and tolerated; others recruit healthy people as a comparison group alongside patients.
250 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteers
Pyloric Sphincter Abnormalities in Patients With Gastroparesis Symptoms
Johns Hopkins Bloomberg School of Public Health
- Location
- Winston-Salem, NC + 4 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingHealthy volunteers
Facial Analysis to Classify Difficult Intubation
Wake Forest University Health Sciences
- Location
- Winston-Salem, NC
- Eligibility basics
- Ages 18–99
- RecruitingHealthy volunteers
Modeling the Effects of Chronic Marijuana Use on Neuroinflammation and HIV-related Neuronal Injury
Wake Forest University Health Sciences
- Location
- Winston-Salem, NC
- Eligibility basics
- Ages 25–59
- RecruitingHealthy volunteers
Neonatal Platelet Transfusion Threshold Trial
NICHD Neonatal Research Network
- Location
- Durham, NC + 19 other US sites
- Eligibility basics
- Any age listed
- RecruitingHealthy volunteers
Advancing Pediatric Retinal Imaging With Auto-aligned OCT
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 1 mo+
- RecruitingHealthy volunteersPhase 4
Femoral Peri-arterial Local Anesthetic Injection Via Peri-arterial Perineural Catheter Reverses Tourniquet Associated Ischemic Hypertension
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 2/Phase 3
Dissolved Phase HXe-129 MRI: A Novel Biomarker to Quantify Pulmonary Pathology
Y. Michael Shim, MD
- Location
- Durham, NC + 1 other US site
- Eligibility basics
- Ages 18–35
- RecruitingHealthy volunteersPhase 4
Safety of RSV Preventive Monoclonal Antibody
Duke University
- Location
- Durham, NC + 4 other US sites
- Eligibility basics
- Ages 1 mo–7 mo
- RecruitingHealthy volunteers
Cervical Cancer Detection Using Optical Spectroscopy
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 18+ · Women only
- RecruitingHealthy volunteers
Pilot Study for Speculum Free Cervical Cancer Screening
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 21–65 · Women only
- RecruitingHealthy volunteers
SenseToKnow Autism Screening Device Validation Study
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 1–3
- RecruitingHealthy volunteers
Telephone-based Physical Activity Coaching or Self Monitored Physical Activity to Improve Physical Function in Older Adults Who Are Undergoing Surgery for Lung Cancer and Their Caregivers
City of Hope Medical Center
- Location
- Durham, NC + 15 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
A Pragmatic Rehabilitation Intervention: The Active Rehab Study
University of North Carolina, Chapel Hill
- Location
- Fort Liberty, NC + 1 other US site
- Eligibility basics
- Ages 18–99
- RecruitingHealthy volunteers
NDPP-NextGen: A Clinical Trial to Reduce Intergenerational Obesity and Diabetes Risks
Wake Forest University Health Sciences
- Location
- Winston-Salem, NC
- Eligibility basics
- Ages 18–39 · Women only
- RecruitingHealthy volunteers
Physical Activity and Community EmPOWERment Project
University of North Carolina, Chapel Hill
- Location
- Chapel Hill, NC
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Take A Break - Rural
Wake Forest University Health Sciences
- Location
- Winston-Salem, NC
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
The Impact of an Evidence-Based Parenting Service on Maternal Sensitivity and Infant Cellular Aging in a Population of Under-Resourced Families
University of Washington
- Location
- Raleigh, NC
- Eligibility basics
- Ages 18+ · Women only
- RecruitingHealthy volunteers
Retinal Imaging in Neurodegenerative Disease
Duke University
- Location
- Durham, NC
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 2
129Xe MRI Cardiopulmonary
Bastiaan Driehuys
- Location
- Durham, NC
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Beat Childhood Cancer Specimen Banking and Data Registry
Giselle Sholler
- Location
- Winston-Salem, NC + 16 other US sites
- Eligibility basics
- Any age listed
- RecruitingHealthy volunteers
Project humAn dieTary daTa rEtuRN
Duke University
- Location
- Durham, NC
- Eligibility basics
- Up to age 1
- RecruitingHealthy volunteers
Development of Quantitative Muscle Imaging as a Biomarker of Disease Endpoints in Myotonic Dystrophy
Wake Forest University Health Sciences
- Location
- Winston-Salem, NC
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteers
Maternal Newborn Health Registry
NICHD Global Network for Women's and Children's Health
- Location
- Chapel Hill, NC + 7 other US sites
- Eligibility basics
- Any age listed
- RecruitingHealthy volunteersPhase 2
Hyperpolarized 129Xe MRI for Imaging Pulmonary Function
Bastiaan Driehuys
- Location
- Durham, NC
- Eligibility basics
- Ages 18+
Who these studies look for
“Healthy” is decided at screening, not by you. Sites usually check vital signs, blood and urine tests, an ECG, your medications and sometimes your BMI or smoking status. A study can still turn you away for reasons that have nothing to do with being unwell, such as timing or a full roster.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do healthy volunteer studies pay?
Many do, because volunteers give up time and follow strict schedules, but amounts are set by each study and are usually only confirmed by the research site. When a record states an amount we show the exact wording; otherwise we say compensation is not disclosed.
What happens at a screening visit?
Expect consent paperwork first, then a health questionnaire, vital signs, blood and urine samples and often an ECG. You can ask questions and withdraw at any time, before or after you sign.