Core: healthy volunteers
Studies for healthy volunteers recruiting now
These studies say in their official record that they accept healthy volunteers. Many are Phase 1 studies that test how a new medicine is absorbed and tolerated; others recruit healthy people as a comparison group alongside patients.
5,002 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingHealthy volunteersPhase 1/Phase 2
Psilocybin Efficacy With or Without Pimavanserin Pretreatment
Johns Hopkins University
- Location
- Baltimore, MD
- Eligibility basics
- Ages 21–65
- RecruitingHealthy volunteersPhase 1
Evaluation of [11C]ZTP-1 to Image PDE4B
National Institute of Mental Health (NIMH)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–101
- RecruitingHealthy volunteersPhase 1
The Gut - PRO Study
University of Wisconsin, Madison
- Location
- Madison, WI
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteersPhase 1
PET Imaging of Noradrenergic Transmission in the Brain
National Institute of Mental Health (NIMH)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–105
- RecruitingHealthy volunteersPhase 1
Evaluation of the Safety and Effects of Psychoactive Substances in People With Past Opioid Use
Christopher D. Verrico
- Location
- Houston, TX
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
: Vascular Function in Health and Disease
D. Walter Wray
- Location
- Salt Lake City, UT
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
Nicotinic Receptor Genetic Variation and Alcohol Reward
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 21–60
- RecruitingHealthy volunteersPhase 1
Induced Blood-Stage Malaria in Healthy Malaria-Naive Adults to Assess the Safety and Infectivity of Plasmodium Vivax Challenge Agent and Evaluate Transmission in Mosquito Feeding Assays
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–54
- RecruitingHealthy volunteersEarly Phase 1
Donor Virus-Specific CMV or AdV CTL to Treat CMV or AdV Reactivation or Disease After Solid Organ or HCT
Sumithira Vasu
- Location
- Columbus, OH
- Eligibility basics
- Ages 1–85
- RecruitingHealthy volunteersPhase 1
Imaging Sex Differences in Smoking-Induced Pulmonary Inflammation
University of Pennsylvania
- Location
- Philadelphia, PA
- Eligibility basics
- Ages 18–45
- RecruitingHealthy volunteersEarly Phase 1
HA35 Acute Alcohol Study
The Cleveland Clinic
- Location
- Cleveland, OH
- Eligibility basics
- Ages 21–65
- RecruitingHealthy volunteersPhase 1/Phase 2
A Phase I-II Study Investigating the All-Oral Combination of the Menin Inhibitor SNDX-5613 With Decitabine/Cedazuridine (ASTX727) and Venetoclax in Acute Myeloid Leukemia (SAVE)
M.D. Anderson Cancer Center
- Location
- Houston, TX
- Eligibility basics
- Ages 12+
- RecruitingHealthy volunteersPhase 1
A Clinical Trial to Evaluate the Safety and Immunogenicity of rVSV∆G-MARV-GP Vaccine in Adults in Good General Health
International AIDS Vaccine Initiative
- Location
- Washington D.C., DC + 1 other US site
- Eligibility basics
- Ages 18–50
- RecruitingHealthy volunteersPhase 1/Phase 2
Brain Network Changes Accompanying and Predicting Responses to Pharmacotherapy in OCD
Yale University
- Location
- New Haven, CT
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1/Phase 2
Human Immune Response to Ixodes Scapularis Tick Bites
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–99
- RecruitingHealthy volunteersPhase 1
Inflammatory Challenge and Fear
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
A Clinical Study to Investigate the Safety and Immunogenicity of rVSV∆G-SUDV-GP, a Sudan Virus (SUDV) Vaccine for the Prevention of SUDV Disease in Adults in Good General Health
International AIDS Vaccine Initiative
- Location
- Washington D.C., DC + 2 other US sites
- Eligibility basics
- Ages 18–50
- RecruitingHealthy volunteersPhase 1
PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease
National Institute of Mental Health (NIMH)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–99
- RecruitingHealthy volunteersPhase 1
Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- San Francisco, CA + 3 other US sites
- Eligibility basics
- Ages 18–60
- RecruitingHealthy volunteersPhase 1
Effects of Various Cannabis Strains on Perceptual, Subjective and Objective Use Outcomes
Johns Hopkins University
- Location
- Baltimore, MD
- Eligibility basics
- Ages 21–55
- RecruitingHealthy volunteersPhase 1
The Impact of Light Exposure on Cognitive Function in Classrooms
Michigan State University
- Location
- East Lansing, MI
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersEarly Phase 1
Imaging Mitochondrial Complex-I in Alcohol Use Disorder
Rajesh Narendran
- Location
- Pittsburgh, PA
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersOvernight stay mentioned
Effect of Physical Activity Pattern on Cardiometabolic Health
Brigham and Women's Hospital
- Location
- Boston, MA
- Eligibility basics
- Ages 18–45
- RecruitingHealthy volunteersPhase 1
Safety and Tolerability Trial of Psilocybin in Healthy Older Adults
University of Colorado, Denver
- Location
- San Francisco, CA + 5 other US sites
- Eligibility basics
- Ages 65–85
Who these studies look for
“Healthy” is decided at screening, not by you. Sites usually check vital signs, blood and urine tests, an ECG, your medications and sometimes your BMI or smoking status. A study can still turn you away for reasons that have nothing to do with being unwell, such as timing or a full roster.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do healthy volunteer studies pay?
Many do, because volunteers give up time and follow strict schedules, but amounts are set by each study and are usually only confirmed by the research site. When a record states an amount we show the exact wording; otherwise we say compensation is not disclosed.
What happens at a screening visit?
Expect consent paperwork first, then a health questionnaire, vital signs, blood and urine samples and often an ECG. You can ask questions and withdraw at any time, before or after you sign.