Core: healthy volunteers
Studies for healthy volunteers recruiting now
These studies say in their official record that they accept healthy volunteers. Many are Phase 1 studies that test how a new medicine is absorbed and tolerated; others recruit healthy people as a comparison group alongside patients.
5,002 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingHealthy volunteersPhase 2Overnight stay mentioned
Effects of Sucralose on Drug Absorption and Metabolism (The SweetMeds Study)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–60 · Women only
- RecruitingHealthy volunteersPhase 1
Membrane Potential Mapping with18F-TPP
Yale University
- Location
- New Haven, CT
- Eligibility basics
- Ages 21–80
- RecruitingHealthy volunteersPhase 1
Acute Effects of THC in Older Adult
Yale University
- Location
- West Haven, CT
- Eligibility basics
- Ages 21+
- RecruitingHealthy volunteersPhase 1/Phase 2
Safety and Immunogenicity of Recombinant Varicella Zoster Virus Vaccine in People With HIV Who Have a CD4 Count Less Than 300 or Greater Than or Equal to 300 and a Healthy Control Population
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
Pilot Study on the Effects of Psilocybin on Belief Updating and Insight Formation
Brown University
- Location
- Providence, RI
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
Investigating the Utility of Demyelination Tracer [18F]3F4AP in Controls and Multiple Sclerosis Subjects
Massachusetts General Hospital
- Location
- Boston, MA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersOvernight stay mentioned
NIMH Rhythms and Blues Study: A Prospective Natural History Study of Motor Activity, Mood States, and Bipolar Disorder
National Institute of Mental Health (NIMH)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 8–70
- RecruitingHealthy volunteersPhase 1
Validation of Nanosensor Oxygen Measurement
Children's Hospital of Philadelphia
- Location
- Philadelphia, PA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
Assessment of [18F]-Fluorocellobiose ([18F]FCB) Pharmacokinetics in Healthy Volunteers and Subjects With Invasive Mold Infections
National Institutes of Health Clinical Center (CC)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–100
- RecruitingHealthy volunteersEarly Phase 1
Entire-body PET Scans for Multiple Sclerosis
Brain Health Alliance
- Location
- Ladera Ranch, CA
- Eligibility basics
- Ages 25–55
- RecruitingHealthy volunteersEarly Phase 1
Testosterone and Neural Function in Men With Spinal Cord Injury
VA Office of Research and Development
- Location
- The Bronx, NY
- Eligibility basics
- Ages 18–80 · Men only
- RecruitingHealthy volunteersPhase 1
The Effects of Cannabidiol on the Driving Performance of Healthy Adults by Dose and Sex
West Virginia University
- Location
- Morgantown, WV
- Eligibility basics
- Ages 18–30
- RecruitingHealthy volunteersPhase 1
Epstein-Barr Virus (EBV) gH/gL/gp42-Ferritin Nanoparticle Vaccine With or Without gp350-Ferritin in Healthy Adults With or Without EBV Infection
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–29
- RecruitingHealthy volunteersEarly Phase 1
Pharmacological Modulation of Brain Oscillations in Memory Processing
University of Texas Southwestern Medical Center
- Location
- Dallas, TX
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersEarly Phase 1
Effect of Neural Constraints on Movement in Stroke
Northwestern University
- Location
- Chicago, IL
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 1
The Role of Glucagon in Glucose Metabolism in Humans With and Without Bariatric Surgery
The University of Texas Health Science Center at San Antonio
- Location
- San Antonio, TX + 1 other US site
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
Effects of Sirolimus on Asymptomatic ApoE4 Carriers
University of Missouri-Columbia
- Location
- Columbia, MO
- Eligibility basics
- Ages 45–65 · Women only
- RecruitingHealthy volunteersOvernight stay mentioned
Development of a Wearable Point of Care Monitoring Device for Pediatric Obstructive Sleep Apnea
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 3–12
- RecruitingHealthy volunteersPhase 1/Phase 2
Neoadjuvant Durvalumab and Tremelimumab With and Without Chemotherapy for Mesothelioma
Baylor College of Medicine
- Location
- Houston, TX
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
Ketamine Pharmacokinetics and Pharmacodynamics for Postpartum Depression and Pain After Cesarean Delivery
University of Utah
- Location
- Salt Lake City, UT
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
Characterization of CB1 Receptors Using [11-C]OMAR in Opioid Use Disorder
Yale University
- Location
- New Haven, CT
- Eligibility basics
- Ages 25–65
- RecruitingHealthy volunteersPhase 1
[18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET
National Institute of Mental Health (NIMH)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 1
Temporal Interference for Thalamocortical Activity and Network Modulation
University of Wisconsin, Madison
- Location
- Madison, WI
- Eligibility basics
- Ages 18–50
- RecruitingHealthy volunteersPhase 1
Role of Alpha-to-beta Cell Communication to Adapt Insulin Secretion to Insulin Resistance.
David D'Alessio, M.D.
- Location
- Durham, NC
- Eligibility basics
- Ages 18–60
Who these studies look for
“Healthy” is decided at screening, not by you. Sites usually check vital signs, blood and urine tests, an ECG, your medications and sometimes your BMI or smoking status. A study can still turn you away for reasons that have nothing to do with being unwell, such as timing or a full roster.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do healthy volunteer studies pay?
Many do, because volunteers give up time and follow strict schedules, but amounts are set by each study and are usually only confirmed by the research site. When a record states an amount we show the exact wording; otherwise we say compensation is not disclosed.
What happens at a screening visit?
Expect consent paperwork first, then a health questionnaire, vital signs, blood and urine samples and often an ECG. You can ask questions and withdraw at any time, before or after you sign.