Weight loss · California
Weight loss and obesity studies in California
96 studies have at least one recruiting site in California. Weight-management research includes trials of new medicines, devices, diets and lifestyle programs for people with overweight or obesity, and studies of weight-related conditions such as fatty liver disease.
96 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 3
A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
Eli Lilly and Company
- Location
- Escondido, CA + 40 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
Eli Lilly and Company
- Location
- Irvine, CA + 55 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight
AstraZeneca
- Location
- Lincoln, CA + 4 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
Amgen
- Location
- Beverly Hills, CA + 117 other US sites
- Eligibility basics
- Ages 18–99
- RecruitingPhase 2
A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus
Corxel Pharmaceuticals
- Location
- Cerritos, CA + 32 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea
Novo Nordisk A/S
- Location
- San Diego, CA + 14 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Research Study Investigating How a New Medicine NNC0113-5840 Works in People With Overweight or Obesity
Novo Nordisk A/S
- Location
- Glendale, CA + 1 other US site
- Eligibility basics
- Ages 18–55
- RecruitingPhase 3
Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body Weight
Novo Nordisk A/S
- Location
- Escondido, CA + 14 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 4
A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice…
Eli Lilly and Company
- Location
- Fountain Valley, CA + 38 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and…
Novo Nordisk A/S
- Location
- Lancaster, CA + 55 other US sites
- Eligibility basics
- Ages 45+
- RecruitingPhase 3
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
Novo Nordisk A/S
- Location
- Alhambra, CA + 129 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
Novo Nordisk A/S
- Location
- Escondido, CA + 17 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Study of ABBV-295 Subcutaneous Injections to Assess Adverse Events and Pharmacokinetics in Adult Participants With Obesity
AbbVie
- Location
- Anaheim, CA + 1 other US site
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1
Examination of How the Duration of Fasting and Temporary Stopping of GLP-1 Medications Affect the Amount of Food Left in the Stomach in People Using Liraglutide (Injected), Semaglutide (Taken by Mouth) or Semaglutide…
Novo Nordisk A/S
- Location
- Cypress, CA
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
Novo Nordisk A/S
- Location
- Walnut Creek, CA + 18 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Research Study on How Well Different Doses of the Medicine UBT251 Help People Living With Overweight or Obesity
Novo Nordisk A/S
- Location
- Cypress, CA + 1 other US site
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteers
Efficacy of mHealth Applications in Weight Management in a Population Affected by Overweight or Obesity
San Diego State University
- Location
- San Diego, CA
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteers
Efficacy of mHealth Apps for Health in a Low-income, Type II Diabetic, Hispanic Population
San Diego State University
- Location
- San Diego, CA
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteers
Efficacy of Using Mobile Health Applications for Health
San Diego State University
- Location
- San Diego, CA
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteers
Promoting Physical Activity and Fitness Among Underserved Latino Families Living in U.S.-Mexico Border Regions
San Diego State University
- Location
- San Diego, CA
- Eligibility basics
- Ages 6+
- RecruitingHealthy volunteers
CHOICE to AVOID or RESIST
Cedars-Sinai Medical Center
- Location
- Beverly Hills, CA
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteers
Medical Residents Learning Weight Management Counseling Skills
University of Massachusetts, Worcester
- Location
- Palo Alto, CA + 6 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Inflammation, Diabetes, Ethnicity and Obesity Cohort
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteers
Effects of Dietary Supplements on Muscle Mass and Function While Using GLP-1 Medication
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 18+
Who these studies look for
Most of these studies set a BMI range and may exclude people taking certain weight-loss medicines or who have had bariatric surgery. Some require a weight-related condition such as type 2 diabetes or high blood pressure.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Can I join a weight loss study if I already take a GLP-1 medicine?
It depends on the study. Many exclude people currently or recently on weight-loss medicines; others are designed specifically for them. The listing’s eligibility criteria and the study team are the only reliable answer.