Study type
Weight loss and obesity studies recruiting now
Weight-management research includes trials of new medicines, devices, diets and lifestyle programs for people with overweight or obesity, and studies of weight-related conditions such as fatty liver disease.
365 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingHealthy volunteersPhase 4
The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With Obesity
Mayo Clinic
- Location
- Jacksonville, FL
- Eligibility basics
- Ages 46–60 · Women only
- RecruitingHealthy volunteers
GENESIS: Genotype Guided - Natriuretic Peptides - Cardiometabolic Health Study
University of Alabama at Birmingham
- Location
- Birmingham, AL
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Efficacy of mHealth Applications in Weight Management in a Population Affected by Overweight or Obesity
San Diego State University
- Location
- San Diego, CA
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteersPhase 2/Phase 3
Food-Body-Mind Intervention (16 Weeks)
Michigan State University
- Location
- Jackson, MI
- Eligibility basics
- Ages 3–5
- RecruitingHealthy volunteers
Exercise Effects on the Neurobiology Underlying Stress-related Eating Behaviors in Veterans
VA Office of Research and Development
- Location
- Aurora, CO
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteers
A Trial to Examine the Effects of a Weight Loss Program Emphasizing Protein, Dietary Fiber, and Exercise (30-30-30 Plan)
Midwest Center for Metabolic and Cardiovascular Research
- Location
- Addison, IL + 2 other US sites
- Eligibility basics
- Ages 18–69
- RecruitingHealthy volunteers
Efficacy of mHealth Apps for Health in a Low-income, Type II Diabetic, Hispanic Population
San Diego State University
- Location
- San Diego, CA
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteers
Efficacy of Using Mobile Health Applications for Health
San Diego State University
- Location
- San Diego, CA
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteers
Promoting Physical Activity and Fitness Among Underserved Latino Families Living in U.S.-Mexico Border Regions
San Diego State University
- Location
- San Diego, CA
- Eligibility basics
- Ages 6+
- RecruitingHealthy volunteers
A Novel Intervention for Weight Loss in Young Adults
University of Chicago
- Location
- Chicago, IL
- Eligibility basics
- Ages 18–40
- RecruitingHealthy volunteers
Wakaya: Rising Up for Choctaw Youth Health
University of Washington
- Location
- Durant, OK + 1 other US site
- Eligibility basics
- Ages 12–19
- RecruitingHealthy volunteers
Two-Week Stair-Climbing Exercise Snacks and Metabolic Health in Adults With Overweight or Obesity: A Pilot Study
St. Louis University
- Location
- St Louis, MO
- Eligibility basics
- Ages 18–35
- RecruitingHealthy volunteers
Physical and Behavioral Traits of Overweight and Obese Adults
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Location
- Bethesda, MD
- Eligibility basics
- Ages 18–100
- RecruitingHealthy volunteers
Comparing Reduction With ESD- Versus APC-TORe
Stephen Firkins
- Location
- Cleveland, OH
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 4
Pioglitazone on Heart Failure in Type-2 Diabetes Mellitus Participants
The University of Texas Health Science Center at San Antonio
- Location
- San Antonio, TX
- Eligibility basics
- Ages 30–70
- RecruitingHealthy volunteers
CHOICE to AVOID or RESIST
Cedars-Sinai Medical Center
- Location
- Beverly Hills, CA
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteers
Impact of Lean Pork on Endothelial Function in Perimenopause
Pennington Biomedical Research Center
- Location
- Baton Rouge, LA
- Eligibility basics
- Ages 40–55 · Women only
- RecruitingHealthy volunteersPhase 2
Semaglutide for Post-Smoking Cessation Weight Management
The University of Texas Health Science Center, Houston
- Location
- Austin, TX + 1 other US site
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteers
Variability In Mixed Meal Tests: Fixed Versus Adjusted to Energy Needs Caloric Dose
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Location
- Phoenix, AZ
- Eligibility basics
- Ages 18–99
- RecruitingHealthy volunteers
Georgia CEAL RESTORES Family Diabetes Study
Morehouse School of Medicine
- Location
- Atlanta, GA
- Eligibility basics
- Ages 12+
- RecruitingHealthy volunteers
Youth-Onset Type 2 Diabetes and Heart Disease: The Young at Heart Prospective Cohort Study
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Location
- Washington D.C., DC + 1 other US site
- Eligibility basics
- Ages 12–25
- RecruitingHealthy volunteers
Pennington Generation Cohort
Pennington Biomedical Research Center
- Location
- Baton Rouge, LA
- Eligibility basics
- Any age listed
- RecruitingHealthy volunteers
Medical Residents Learning Weight Management Counseling Skills
University of Massachusetts, Worcester
- Location
- Palo Alto, CA + 6 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Cottonseed Oil Versus Matched PUFA Effects
University of Georgia
- Location
- Athens, GA
- Eligibility basics
- Ages 25–75
Who these studies look for
Most of these studies set a BMI range and may exclude people taking certain weight-loss medicines or who have had bariatric surgery. Some require a weight-related condition such as type 2 diabetes or high blood pressure.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Can I join a weight loss study if I already take a GLP-1 medicine?
It depends on the study. Many exclude people currently or recently on weight-loss medicines; others are designed specifically for them. The listing’s eligibility criteria and the study team are the only reliable answer.