Location · California
Clinical trials recruiting in California
1898 recruiting studies have at least one site in California; 701 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,898 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 3
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)
Bristol-Myers Squibb
- Location
- Anaheim, CA + 21 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 3
A Long-Term Study to Learn About The Study Medicine Called Ritlecitinib in Children With Severe Alopecia Areata.
Pfizer
- Location
- Irvine, CA + 18 other US sites
- Eligibility basics
- Ages 6–14
- Recruiting
Study of the Shockwave Medical SkyRunner Carotid Intravascular Lithotripsy (IVL) System for the Treatment of Calcified Carotid Arteries Prior to Trans-Carotid Stenting (SKYWARD Trans-Carotid IDE [Investigational Device…
Shockwave Medical, Inc.
- Location
- Rancho Mirage, CA + 16 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Clinical Study to Evaluate the Safety and Effectiveness of Arcevo LSA
Artivion Inc.
- Location
- Los Angeles, CA + 21 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
Efficacy and Safety of 4F-PCC (4-Factor Prothrombin Complex Concentrate) in Adult Patients Undergoing Complex Cardiovascular Surgery With Cardiopulmonary Bypass (CPB)
CSL Behring
- Location
- Los Angeles, CA + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate the Safety and Efficacy of MK-1406/CD388 for Prevention of Influenza (MK-1406-005/CD388.SQ.3.06)
Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
- Location
- Fullerton, CA + 51 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 3
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
Alnylam Pharmaceuticals
- Location
- Beverly Hills, CA + 213 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc Disease
DiscGenics, Inc.
- Location
- San Diego, CA + 29 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study to Evaluate the Long-term Safety and Tolerability of Xanomeline and Trospium Chloride for the Treatment of Psychiatric Disorders in Children and Adolescents
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- Location
- Anaheim, CA + 12 other US sites
- Eligibility basics
- Ages 5–17
- RecruitingPhase 3
Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)
Bausch Health Americas, Inc.
- Location
- Los Angeles, CA + 36 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Long-Term Open-Label Study of ML-007C-MA in Adults With Schizophrenia
MapLight Therapeutics
- Location
- Bellflower, CA + 41 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
Efficacy and Safety Study to Evaluate SD-101 in Epidermolysis Bullosa
Paradigm Therapeutics
- Location
- Rancho Santa Margarita, CA + 3 other US sites
- Eligibility basics
- Ages 1 mo–12
- RecruitingPhase 3
A Study to Evaluate the Efficacy of NIO752 in Participants With Progressive Supranuclear Palsy
Novartis Pharmaceuticals
- Location
- San Francisco, CA + 8 other US sites
- Eligibility basics
- Ages 41–81
- RecruitingPhase 3
A Phase 3 Study of INCA033989 Versus Best Available Therapy in Participants With Essential Thrombocythemia
Incyte Corporation
- Location
- Duarte, CA + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study of GS-3242 in Combination With Lenacapavir Versus Biktarvy in Virologically Suppressed People With HIV-1
Gilead Sciences
- Location
- Beverly Hills, CA + 40 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Learn About the Study Medicine Called Tilrekimig in People With Moderate-to-Severe Eczema
Pfizer
- Location
- Northridge, CA + 7 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 2
Dose-finding Study of YMI024 to Assess Efficacy, Safety, and Tolerability in Adults With Stable Coronary Artery Disease and Elevated hsCRP
Novartis Pharmaceuticals
- Location
- Los Angeles, CA + 8 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
Study to Assess the Effect and Safety of ALV-100 on Maintenance of Weight Loss
Alveus Therapeutics, Inc.
- Location
- Oceanside, CA + 19 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
Accuro XV Ultrasound Imaging System for BoneEnhance and Fracture Detection Algorithms
Rivanna Medical, Inc.
- Location
- San Francisco, CA + 9 other US sites
- Eligibility basics
- Ages 5+
- RecruitingPhase 3
Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects
Pfizer
- Location
- Hawthorne, CA + 28 other US sites
- Eligibility basics
- Ages 6–17
- RecruitingPhase 2
A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette);
Genentech, Inc.
- Location
- Beverly Hills, CA + 14 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Boehringer Ingelheim
- Location
- Chula Vista, CA + 91 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis
Boehringer Ingelheim
- Location
- Canoga Park, CA + 154 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis
Boehringer Ingelheim
- Location
- Canoga Park, CA + 123 other US sites
- Eligibility basics
- Ages 18+