Location · California
Clinical trials recruiting in California
1900 recruiting studies have at least one site in California; 700 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,900 recruiting studiesSource: ClinicalTrials.gov, refreshed October 27, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 2
A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)
Seaport Therapeutics
- Location
- Chino, CA + 26 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease
Hoffmann-La Roche
- Location
- Fullerton, CA + 52 other US sites
- Eligibility basics
- Ages 50–85
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (EMERGENT TEEN)
Bristol-Myers Squibb
- Location
- Anaheim, CA + 12 other US sites
- Eligibility basics
- Ages 13–17
- RecruitingPhase 2
Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)
Sparrow Pharmaceuticals
- Location
- Fountain Valley, CA + 60 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Pridopidine Phase 3 Study to Evaluate Efficacy and Safety in ALS
Prilenia
- Location
- San Francisco, CA + 17 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma
Kymera Therapeutics, Inc.
- Location
- Lancaster, CA + 30 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease
EMD Serono Research & Development Institute, Inc.
- Location
- Los Angeles, CA + 11 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2)
EMD Serono Research & Development Institute, Inc.
- Location
- Upland, CA + 13 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophilia A
Hoffmann-La Roche
- Location
- Orange, CA + 9 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 2
A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations
Appello Pharmaceuticals, Inc.
- Location
- Carlsbad, CA + 29 other US sites
- Eligibility basics
- Ages 30–80
- RecruitingPhase 2
Phase 2 Study to Assess the Safety and Efficacy of ANG003
Anagram Therapeutics, Inc.
- Location
- Long Beach, CA + 19 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 3
A Study to Learn About the Study Medicine Called Tilrekimig in People With Severe Asthma
Pfizer
- Location
- Bakersfield, CA + 6 other US sites
- Eligibility basics
- Ages 12–80
- RecruitingPhase 4
Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Children With ADHD
Supernus Pharmaceuticals, Inc.
- Location
- Anaheim, CA + 38 other US sites
- Eligibility basics
- Ages 4–5
- RecruitingPhase 3
Safety Evaluation of Prismocitrate 18 in Patients Receiving CRRT
Vantive Health LLC
- Location
- Los Angeles, CA + 6 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Multi-center Trial of Ferric Derisomaltose Versus no Intravenous Iron in Iron-deficient Subjects With Symptomatic Chronic Heart Failure
Pharmacosmos A/S
- Location
- Pasadena, CA
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation
GlaxoSmithKline
- Location
- Bakersfield, CA + 36 other US sites
- Eligibility basics
- Ages 40–80
- RecruitingPhase 2
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
Novo Nordisk A/S
- Location
- Covina, CA + 16 other US sites
- Eligibility basics
- Ages 40–84
- Recruiting
Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
Boston Scientific Corporation
- Location
- La Jolla, CA + 39 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD)
Disc Medicine, Inc
- Location
- San Francisco, CA + 10 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy
Kardigan, Inc.
- Location
- Los Angeles, CA + 26 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Phase 2 EL219 Versus Liposomal Amphotericin B or Voriconazole for Early Antifungal Therapy
Elion Therapeutics, Inc.
- Location
- Sacramento, CA + 9 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Pivotal Study of the Silk Vista Baby Flow Diverters in the Treatment of Unruptured Intracranial Aneurysms (PIONEER)
Balt USA
- Location
- Thousand Oaks, CA + 4 other US sites
- Eligibility basics
- Ages 22–80
- RecruitingPhase 2
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study With an Open-Label Extension Evaluating the Efficacy and Safety of VENT-03 in Adult Participants With Active Cutaneous Lupus Erythematosus With…
Ventus Therapeutics U.S., Inc.
- Location
- Beverly Hills, CA + 14 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response
ACADIA Pharmaceuticals Inc.
- Location
- Chino, CA + 23 other US sites
- Eligibility basics
- Ages 18–65