Location · California
Clinical trials recruiting in California
1900 recruiting studies have at least one site in California; 700 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,900 recruiting studiesSource: ClinicalTrials.gov, refreshed October 27, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 2
EncompaSSc: Evaluation of MTX-474 in Participants With Diffuse Cutaneous Systemic Sclerosis (dcSSc)
Mediar Therapeutics
- Location
- Los Angeles, CA + 13 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
Eli Lilly and Company
- Location
- Moorpark, CA + 31 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Phase III Study to Assess the Effect of FDC Laroprovstat/Rosuvastatin Compared With Rosuvastatin on LDL-C in Patients With Hypercholesterolaemia
AstraZeneca
- Location
- Pomona, CA + 8 other US sites
- Eligibility basics
- Ages 18–130
- RecruitingPhase 2
Evaluation of YB-101 for Safety, Tolerability, Pharmacokinetics, and Efficacy in Graves' Disease
Yarrow Bioscience, Inc.
- Location
- La Mesa, CA + 21 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)
Amgen
- Location
- Canoga Park, CA + 30 other US sites
- Eligibility basics
- Ages 18–99
- RecruitingPhase 3
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)
Amgen
- Location
- Fountain Valley, CA + 69 other US sites
- Eligibility basics
- Ages 18–99
- RecruitingPhase 3
CAR-T Long Term Follow Up (LTFU) Study
Novartis Pharmaceuticals
- Location
- Duarte, CA + 38 other US sites
- Eligibility basics
- Ages 0 mo–100
- RecruitingPhase 1/Phase 2
A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis
Sumitomo Pharma America, Inc.
- Location
- Duarte, CA + 29 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen
AstraZeneca
- Location
- Fresno, CA + 30 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
Orchestra BioMed, Inc
- Location
- Glendale, CA + 15 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
Clinical Study of SNK01 in Participants With Moderate Alzheimer's Disease
NKGen Biotech, Inc.
- Location
- Glendale, CA + 5 other US sites
- Eligibility basics
- Ages 40–85
- RecruitingPhase 3
A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease
AstraZeneca
- Location
- Castroville, CA + 120 other US sites
- Eligibility basics
- Ages 40–80
- Recruiting
ELEVATE-HFpEF Clinical Study
Medtronic Cardiac Rhythm and Heart Failure
- Location
- Palo Alto, CA + 25 other US sites
- Eligibility basics
- Ages 40+
- RecruitingPhase 2
A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease
Neuron23 Inc.
- Location
- Fresno, CA + 43 other US sites
- Eligibility basics
- Ages 40–80
- RecruitingPhase 2
An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL)
Avalyn Pharma Inc.
- Location
- Los Angeles, CA + 30 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy
Scholar Rock, Inc.
- Location
- Orange, CA + 11 other US sites
- Eligibility basics
- Up to age 2
- RecruitingPhase 2
A Study to Evaluate the Efficacy, Safety, and PK of AZD0292 Administered IV in Participants 12 Years of Age and Older With Bronchiectasis and Chronic Pseudomonas Aeruginosa Colonization
AstraZeneca
- Location
- Orange, CA + 15 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 2
A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension
Retension Pharmaceuticals. Inc.
- Location
- San Jose, CA + 31 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2/Phase 3
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
EyeBiotech Ltd.
- Location
- Glendale, CA + 66 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety in Participants Aged 15 to 60 Years With Spinal Muscular Atrophy (SMA) Who Are Either New to SMA Treatment or Were Previously Treated With…
Biogen
- Location
- Palo Alto, CA + 1 other US site
- Eligibility basics
- Ages 15–60
- RecruitingPhase 2
Study of EVO756 in Adults With Migraine
Evommune, Inc.
- Location
- Buena Park, CA + 32 other US sites
- Eligibility basics
- Ages 18–64
- RecruitingPhase 3
Rollover Study for Participants Who Have Completed a Previous Clinical Study With Anifrolumab (Saphnelo) and Clinically Benefited From Continued Treatment
AstraZeneca
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 5–80
- RecruitingPhase 3
A Study of the Long-term Safety and Efficacy of Danicamtiv in Adults With Symptomatic Genetic and Familial Dilated Cardiomyopathy
Kardigan, Inc.
- Location
- Los Angeles, CA + 2 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
RENAISSANCE 2: SPN-817 Phase 2, Double-Blind, Placebo-Controlled Study in Adults With Focal Onset Seizures
Supernus Pharmaceuticals, Inc.
- Location
- Los Angeles, CA + 36 other US sites
- Eligibility basics
- Ages 18–70