Location · California
Clinical trials recruiting in California
1900 recruiting studies have at least one site in California; 700 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,900 recruiting studiesSource: ClinicalTrials.gov, refreshed October 27, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 2
A Study of TYRA-300 in Children With Achondroplasia: BEACH301
Tyra Biosciences, Inc
- Location
- Torrance, CA + 11 other US sites
- Eligibility basics
- Ages 3–10
- RecruitingPhase 2
A 16-week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream 20 mg/g in Adult Participants With Mild to Severe Palmoplantar Pustulosis
LEO Pharma
- Location
- Fountain Valley, CA + 6 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Comparing the Efficacy and Safety of the EndoZip System and Apollo ESG in Obese Patients
Nitinotes Surgical Ltd.
- Location
- Los Angeles, CA + 3 other US sites
- Eligibility basics
- Ages 21–65
- RecruitingPhase 1
A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy
Rocket Pharmaceuticals Inc.
- Location
- San Diego, CA + 2 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
A Study to Investigate Mibavademab in Adult Women With Functional Hypothalamic Amenorrhea
Regeneron Pharmaceuticals
- Location
- West Hills, CA + 9 other US sites
- Eligibility basics
- Ages 18–40 · Women only
- RecruitingPhase 2
A Study of Praliciguat in Participants With Focal Segmental Glomerulosclerosis (FSGS)
Akebia Therapeutics
- Location
- Chula Vista, CA + 28 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Hetrombopag Olamine Tablets Vs Placebo in Patients With Chemotherapy-Induced Thrombocytopenia (ExCIT)
Jiangsu HengRui Medicine Co., Ltd.
- Location
- Los Alamitos, CA + 7 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
MBA Early Feasibility Study
W.L.Gore & Associates
- Location
- Los Angeles, CA + 2 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Major Depressive Disorder
Janssen Research & Development, LLC
- Location
- Bellflower, CA + 33 other US sites
- Eligibility basics
- Ages 18–74
- RecruitingPhase 3
A Phase 3 Study of Inebilizumab in Participants With Primary Membranous Nephropathy
Amgen
- Location
- Los Angeles, CA + 3 other US sites
- Eligibility basics
- Ages 18–79
- Recruiting
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II
Shockwave Medical, Inc.
- Location
- Los Angeles, CA + 66 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/VI in 12-17-year-olds With Asthma
GlaxoSmithKline
- Location
- Bakersfield, CA + 18 other US sites
- Eligibility basics
- Ages 12–17
- RecruitingPhase 3
An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants
AstraZeneca
- Location
- Los Angeles, CA + 18 other US sites
- Eligibility basics
- Ages 5–17
- RecruitingPhase 4
A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis
Amgen
- Location
- Fremont, CA + 57 other US sites
- Eligibility basics
- Ages 18–100
- RecruitingPhase 2/Phase 3
A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
Janssen Research & Development, LLC
- Location
- Fullerton, CA + 44 other US sites
- Eligibility basics
- Ages 60+
- RecruitingPhase 2
A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis
MapLight Therapeutics
- Location
- Anaheim, CA + 32 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 2
Imeroprubart in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Immunovant Sciences GmbH
- Location
- Carlsbad, CA + 30 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study of Zasocitinib in Adults With Nonsegmental Vitiligo
Takeda
- Location
- Fountain Valley, CA + 20 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
A Study of AAVB-039 in Participants With Stargardt Disease (STGD1)
AAVantgarde Bio Srl
- Location
- Los Angeles, CA + 7 other US sites
- Eligibility basics
- Ages 8–55
- RecruitingPhase 3
Trial Investigating the Efficacy and Safety of Weekly Lonapegsomatropin Compared to Daily Somatropin in Children and Adolescents With Short Stature or Growth Failure Due to Growth Hormone Sufficient Disorders
Ascendis Pharma A/S
- Location
- Palo Alto, CA + 21 other US sites
- Eligibility basics
- Ages 2–17
- Recruiting
A Study Assessing Long-Term Safety and Effectiveness in Treatment Management of Atrial Fibrillation With VARIPULSE Catheter System
Biosense Webster, Inc.
- Location
- Fountain Valley, CA + 22 other US sites
- Eligibility basics
- Ages 22+
- RecruitingPhase 3
A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight
Novo Nordisk A/S
- Location
- Escondido, CA + 26 other US sites
- Eligibility basics
- Ages 8–18
- RecruitingPhase 1
NEXUS Study: A Study to Test Single and Multiple Doses of MER511 Given to Adults With Graves' Disease
Merida Biosciences
- Location
- Torrance, CA + 10 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight
Novo Nordisk A/S
- Location
- Lomita, CA + 13 other US sites
- Eligibility basics
- Ages 18+