Location · California
Clinical trials recruiting in California
1900 recruiting studies have at least one site in California; 700 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,900 recruiting studiesSource: ClinicalTrials.gov, refreshed October 27, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 2
To Evaluate the Effect of EXPD-101/FXS7553 Compared With Placebo in Patients With COPD Over 52 Weeks of Treatment
Expedition Therapeutics, Inc
- Location
- Northridge, CA + 21 other US sites
- Eligibility basics
- Ages 40–85
- RecruitingPhase 3
A Pivotal Clinical Study to Investigate the Safety and Efficacy of Efimosfermin Compared With Placebo in Adult Participants With Compensated Cirrhosis Due to Metabolic Dysfunction-associated Steatohepatitis (MASH)
GlaxoSmithKline
- Location
- Folsom, CA + 10 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study to Investigate Safety and Efficacy of Efimosfermin Compared With Placebo in Adult Participants With Compensated Cirrhosis Due to Metabolic Dysfunction-associated Steatohepatitis (MASH)
GlaxoSmithKline
- Location
- Folsom, CA + 15 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Research Study on How People With Type 2 Diabetes Tolerate Switching From Semaglutide to Cagrisema
Novo Nordisk A/S
- Location
- Fountain Valley, CA + 36 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Post-Market Study to Assess iTind Safety in Comparison to UroLift
Olympus Corporation of the Americas
- Location
- Fresno, CA + 10 other US sites
- Eligibility basics
- Ages 50+ · Men only
- RecruitingPhase 3
Gene Therapy Trial for Otoferlin Gene-mediated Hearing Loss
Eli Lilly and Company
- Location
- San Francisco, CA + 2 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 3
ATSN-201 Gene Therapy in RS1-Associated X-linked Retinoschisis
Atsena Therapeutics Inc.
- Location
- Los Angeles, CA + 13 other US sites
- Eligibility basics
- Ages 5+
- RecruitingPhase 3
VE303 for Prevention of Recurrent Clostridioides Difficile Infection
Vedanta Biosciences, Inc.
- Location
- Culver City, CA + 55 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 2
A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease
Intra-Cellular Therapies, Inc.
- Location
- Anaheim, CA + 17 other US sites
- Eligibility basics
- Ages 55+
- RecruitingPhase 2
A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation Associated With Alzheimer's Dementia
Intra-Cellular Therapies, Inc.
- Location
- Anaheim, CA + 22 other US sites
- Eligibility basics
- Ages 55+
- RecruitingPhase 3
A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Primary Membranous Nephropathy (PMN)
Biogen
- Location
- Fresno, CA + 14 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
Phase 2, Efficacy and Safety Study of ACP-204 in Lewy Body Dementia Psychosis
ACADIA Pharmaceuticals Inc.
- Location
- Irvine, CA + 27 other US sites
- Eligibility basics
- Ages 55–84
- RecruitingPhase 3
Phase 3, Open Label Extension Study of ACP-204 in Lewy Body Dementia Psychosis
ACADIA Pharmaceuticals Inc.
- Location
- Irvine, CA + 17 other US sites
- Eligibility basics
- Ages 55–84
- RecruitingPhase 3
A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis
Regeneron Pharmaceuticals
- Location
- San Francisco, CA + 12 other US sites
- Eligibility basics
- Ages 6 mo–6
- RecruitingPhase 1
A Study of SGT-212 Gene Therapy in Friedreich's Ataxia
Solid Biosciences Inc.
- Location
- Los Angeles, CA + 2 other US sites
- Eligibility basics
- Ages 18–40
- RecruitingPhase 2
Study of MRM-3379 in Male Participants With Fragile X Syndrome (BLOOM)
Mirum Pharmaceuticals, Inc.
- Location
- Irvine, CA + 13 other US sites
- Eligibility basics
- Ages 13–45 · Men only
- RecruitingPhase 2
A Study to Investigate the Clinical Effect and the Safety of PRX-115 Infused Intravenously at Different Dosing Regimens, With and Without Methotrexate, Versus Placebo in Adults Gout Patients (RELEASE)
Protalix
- Location
- Anaheim, CA + 25 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
An Assessment of Efficacy, Safety, and Pharmacokinetics of NBI-1117568 in Adults With Bipolar I Disorder With Current Mania
Neurocrine Biosciences
- Location
- Cerritos, CA + 10 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events
Genentech, Inc.
- Location
- Beverly Hills, CA + 23 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Phase 2a Study of ALN-PNP With and Without a GLP1R Agonist in Adult Patients With Homozygous PNPLA3-Related MASLD
Regeneron Pharmaceuticals
- Location
- Coronado, CA + 8 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
kTMP-Enhanced Motor Rehabilitation for Chronic Stroke Recovery (KULMINATE) Pilot
Magnetic Tides
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
A Study to Asses Safety and Tolerability of ITI-1284 Given Alone or as an Additional Treatment in Participants With Generalized Anxiety Disorder (GAD)
Intra-Cellular Therapies, Inc.
- Location
- Los Angeles, CA + 2 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Phase 1 Study of VK3019 in Overweight and Obese Adults Without Comorbidities
Viking Therapeutics, Inc.
- Location
- Lake Forest, CA
- Eligibility basics
- Ages 18–60
- RecruitingPhase 3
Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-Resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass
Octapharma
- Location
- Stanford, CA + 8 other US sites
- Eligibility basics
- Ages 18–85