Location · California
Clinical trials recruiting in California
1900 recruiting studies have at least one site in California; 700 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,900 recruiting studiesSource: ClinicalTrials.gov, refreshed October 27, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 2
Platform Study to Evaluate the Efficacy and Safety of Investigational Compound(s) in Patients With Moderate to Severe Atopic Dermatitis
Novartis Pharmaceuticals
- Location
- Fountain Valley, CA + 22 other US sites
- Eligibility basics
- Ages 18–100
- RecruitingPhase 2
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)
Genentech, Inc.
- Location
- Lancaster, CA + 7 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease (NPC)
Azafaros B.V.
- Location
- Oakland, CA + 4 other US sites
- Eligibility basics
- Ages 4+
- RecruitingPhase 3
A Study of Dotinurad Versus Allopurinol in Participants With Gout
Crystalys Therapeutics
- Location
- Covina, CA + 81 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study of Dotinurad Versus Allopurinol in Tophaceous Gout
Crystalys Therapeutics
- Location
- Covina, CA + 82 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study of NNZ-2591 in Pediatric Participants With Phelan-McDermid Syndrome
Neuren Pharmaceuticals Limited
- Location
- Glendale, CA + 16 other US sites
- Eligibility basics
- Ages 3–12
- RecruitingPhase 3
A Study to Investigate the Efficacy, Pharmacokinetics, and Safety of Mitapivat in Pediatric Participants With α- or β-Non-Transfusion-Dependent Thalassemia
Agios Pharmaceuticals, Inc.
- Location
- Palo Alto, CA + 4 other US sites
- Eligibility basics
- Ages 1–17
- RecruitingPhase 2
A Phase 2 Trial of Dotinurad in Xanthine Oxidase Inhibitor (XOI) Intolerant/Uricase Failure Gout Participants
Crystalys Therapeutics
- Location
- Granada Hills, CA + 40 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2/Phase 3
Phase 2/3 Clinical Study of QRX003 Lotion in Subjects With Netherton Syndrome
Quoin Pharmaceuticals
- Location
- Fremont, CA + 3 other US sites
- Eligibility basics
- Ages 4+
- RecruitingPhase 1
A Study of the Feasibility, Safety and Tolerability of Aticaprant as Adjunctive Treatment in Participants With Schizophrenia
Janssen Research & Development, LLC
- Location
- Garden Grove, CA + 7 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingPhase 3
A Study to Investigate Cabotegravir Ultra Long-Acting (CAB ULA) Plus Rilpivirine Ultra Long-Acting (RPV ULA) in Adults and Adolescents With HIV Who Are Virologically Suppressed
ViiV Healthcare
- Location
- Bakersfield, CA + 36 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 3
A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide
Novo Nordisk A/S
- Location
- Lancaster, CA + 32 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight
Novo Nordisk A/S
- Location
- Fullerton, CA + 38 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
AstraZeneca
- Location
- Lomita, CA + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Acute Femoropopliteal DVT
Mercator MedSystems, Inc.
- Location
- Orange, CA + 17 other US sites
- Eligibility basics
- Ages 18–89
- RecruitingPhase 3
Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder
Intra-Cellular Therapies, Inc.
- Location
- Pico Rivera, CA + 19 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
A Study of Nipocalimab in Pregnancies at Risk for Severe Hemolytic Disease of the Fetus and Newborn (HDFN)
Janssen Research & Development, LLC
- Location
- La Jolla, CA + 19 other US sites
- Eligibility basics
- Ages 18–45 · Women only
- RecruitingPhase 3
A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease
Janssen Research & Development, LLC
- Location
- Los Angeles, CA + 8 other US sites
- Eligibility basics
- Ages 2–17
- Recruiting
Study of GalaFLEX LITE™ Scaffold in Treatment of Capsular Contracture After Breast Implant Augmentation
C. R. Bard
- Location
- Beverly Hills, CA + 32 other US sites
- Eligibility basics
- Ages 22–70 · Women only
- Recruiting
Early Feasibility Study (EFS) Laplace Transcatheter Tricuspid Valve Replacement (TTVR) System
Laplace Interventional, Inc
- Location
- San Francisco, CA + 9 other US sites
- Eligibility basics
- Ages 18–90
- RecruitingPhase 3
Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum Disorder
Intra-Cellular Therapies, Inc.
- Location
- Anaheim, CA + 46 other US sites
- Eligibility basics
- Ages 5–17
- RecruitingPhase 2
A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease
Takeda
- Location
- Murrieta, CA + 23 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients
Intra-Cellular Therapies, Inc.
- Location
- Anaheim, CA + 33 other US sites
- Eligibility basics
- Ages 10–17
- RecruitingPhase 2
Study of ITI-1284 as an Adjunctive Treatment in Patients With Generalized Anxiety Disorder
Intra-Cellular Therapies, Inc.
- Location
- Glendale, CA + 24 other US sites
- Eligibility basics
- Any age listed