Location · California
Clinical trials recruiting in California
1900 recruiting studies have at least one site in California; 700 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,900 recruiting studiesSource: ClinicalTrials.gov, refreshed October 27, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 3
A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)
Janssen Research & Development, LLC
- Location
- Sacramento, CA + 11 other US sites
- Eligibility basics
- Ages 18–45 · Women only
- RecruitingPhase 2
Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease
AbbVie
- Location
- Coronado, CA + 53 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms
Janssen Research & Development, LLC
- Location
- Anaheim, CA + 41 other US sites
- Eligibility basics
- Ages 18–74
- RecruitingPhase 3
Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder in Pediatric Patients
Intra-Cellular Therapies, Inc.
- Location
- Anaheim, CA + 27 other US sites
- Eligibility basics
- Ages 5–17
- RecruitingPhase 2
Study of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety Disorder
Intra-Cellular Therapies, Inc.
- Location
- Culver City, CA + 22 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder (ASD) in Pediatric Patients
Intra-Cellular Therapies, Inc.
- Location
- Sacramento, CA + 26 other US sites
- Eligibility basics
- Ages 5–17
- RecruitingPhase 4
Open-Label Study to Assess Safety and Time to Catheter-related Bloodstream Infections (CRBSI) in Subjects From Birth to < 18 Years of Age
CorMedix Therapeutics
- Location
- Palo Alto, CA + 5 other US sites
- Eligibility basics
- Up to age 17
- Recruiting
MMA Embolization for Refractory Chronic Migraine
Cerenovus, Part of DePuy Synthes Products, Inc.
- Location
- Walnut Creek, CA + 7 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
AstraZeneca
- Location
- Beverly Hills, CA + 104 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of the Medicine Called Abrocitinib in Children 6 to Less Than 12 Years of Age With Moderate-to-Severe Eczema
Pfizer
- Location
- San Diego, CA + 12 other US sites
- Eligibility basics
- Ages 6–11
- RecruitingPhase 3
Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults And Adolescent Participants Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)
CorMedix Therapeutics
- Location
- Los Angeles, CA + 16 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 2
Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids
AstraZeneca
- Location
- Bakersfield, CA + 21 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 4
Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants
Neurotech Pharmaceuticals
- Location
- Palo Alto, CA + 15 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of GIGA-2339 in Participants With Chronic Hepatitis B Virus Infection
GigaGen, Inc.
- Location
- Huntington Beach, CA + 10 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
FIBERGRAFT Aeridyan Posterolateral Fusion Study
DePuy Synthes Products, Inc.
- Location
- Sacramento, CA + 4 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
NBI-1117568-SCZ3030: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia
Neurocrine Biosciences
- Location
- Culver City, CA + 5 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
NBI-1117568-SCZ3032: Long-Term Evaluation of NBI-1117568 in Adults With Schizophrenia
Neurocrine Biosciences
- Location
- Cerritos, CA + 44 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2/Phase 3
A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease
Janssen Research & Development, LLC
- Location
- Anaheim, CA + 53 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis
Janssen Research & Development, LLC
- Location
- Anaheim, CA + 50 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 3
Comparative Efficacy of Nipocalimab and Efgartigimod in Participants With Generalized Myasthenia Gravis
Janssen Research & Development, LLC
- Location
- Fullerton, CA + 14 other US sites
- Eligibility basics
- Ages 18–74
- RecruitingPhase 3
Efficacy of NBI-1117568 in Preventing Relapse in Adults With Schizophrenia
Neurocrine Biosciences
- Location
- Garden Grove, CA + 18 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
Study of ENV-294 in Adults With Moderate-to-Severe Atopic Dermatitis
Enveda Therapeutics
- Location
- Beverly Hills, CA + 29 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Study to Evaluate the Efficacy and Safety of JNJ-88545223 for the Treatment of Participants With Active Psoriatic Arthritis
Janssen Research & Development, LLC
- Location
- Huntington Beach, CA + 17 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Transcatheter Tricuspid Valve Replacement With the Medtronic Intrepid™ Transcatheter Tricuspid Valve Replacement (TTVR) System in Severe Tricuspid Regurgitation
Medtronic Cardiovascular
- Location
- Thousand Oaks, CA + 12 other US sites
- Eligibility basics
- Ages 18+