Location · California
Clinical trials recruiting in California
1900 recruiting studies have at least one site in California; 700 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,900 recruiting studiesSource: ClinicalTrials.gov, refreshed October 27, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 2/Phase 3
A Study of TAK-360 in People With Narcolepsy or Idiopathic Hypersomnia
Takeda
- Location
- Chula Vista, CA + 16 other US sites
- Eligibility basics
- Ages 18–71
- RecruitingPhase 3
A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease
Novo Nordisk A/S
- Location
- Los Angeles, CA + 42 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 3
A Clinical Study to Investigate the Safety and Tolerability of Efimosfermin Alfa Injection in Participants With Known or Suspected F2- or F3-stage MASH
GlaxoSmithKline
- Location
- Arcadia, CA + 46 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1)
Transcend Therapeutics
- Location
- Imperial, CA + 36 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Romiplostim Plus Predniso(lo)ne vs. Predniso(lo)ne Alone for the Treatment of Previously Untreated Primary Immune Thrombocytopenia (ITP)
Amgen
- Location
- Long Beach, CA + 2 other US sites
- Eligibility basics
- Ages 18–100
- Recruiting
Thermoregulatory Physiology of Menopausal Hot Flashes
SRI International
- Location
- Menlo Park, CA
- Eligibility basics
- Ages 40–65 · Women only
- RecruitingPhase 3
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
Amgen
- Location
- Beverly Hills, CA + 117 other US sites
- Eligibility basics
- Ages 18–99
- RecruitingPhase 1
A Study to Assess Adverse Events and How Oral ABBV-932 Moves Through the Body When Given With Oral Itraconazole in Adult Participants With Bipolar Disorder
AbbVie
- Location
- Los Alamitos, CA
- Eligibility basics
- Ages 18–65
- Recruiting
Post-market Safety and Effectiveness of the CORUS-LX System in Improving Lumbar Interbody Fusion Outcomes
Providence Medical Technology, Inc.
- Location
- Los Angeles, CA + 9 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Crinecerfont in Participants With Classic Congenital Adrenal Hyperplasia (CAH) Who Are Less Than 4 Years Old
Neurocrine Switzerland GmbH
- Location
- San Francisco, CA + 10 other US sites
- Eligibility basics
- Ages 4 mo–3
- RecruitingPhase 3
Brexanolone Lifting Outcomes Of Moms
Lipocine Inc.
- Location
- Canoga Park, CA + 15 other US sites
- Eligibility basics
- Ages 15–45 · Women only
- Recruiting
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.
Medtronic Cardiovascular
- Location
- La Jolla, CA + 68 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome
Epygenix
- Location
- Orange, CA + 16 other US sites
- Eligibility basics
- Ages 2+
- RecruitingPhase 3
Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke
Pharmazz, Inc.
- Location
- Carmichael, CA + 13 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
A Study to Understand How the Study Medicine (PF-06823859) Works in People With Active Idiopathic Inflammatory Myopathies [Dermatomyositis (DM) and Polymyositis (PM)]
Pfizer
- Location
- Los Angeles, CA + 31 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy
NaviFUS Corporation
- Location
- Palo Alto, CA + 2 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Assess Adverse Events, Change in Disease Activity, and How Oral Emraclidine Moves Through the Body in Adult Participants With Schizophrenia
AbbVie
- Location
- Glendale, CA + 6 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus
Corxel Pharmaceuticals
- Location
- Cerritos, CA + 32 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
A Study of VARIPULSE Pulsed Field Ablation (PFA) Catheter and FARAWAVE PFA Catheter in the Treatment of Participants With Persistent Atrial Fibrillation
Biosense Webster, Inc.
- Location
- Fountain Valley, CA + 9 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2/Phase 3
A Study to Investigate PORT-77 Oral Dosing Compared With Placebo in Participants With Erythropoietic Protoporphyria (EPP) or X-linked Protoporphyria (XLP)
Portal Therapeutics, Inc.
- Location
- Huntington Beach, CA + 1 other US site
- Eligibility basics
- Ages 12+
- Recruiting
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial
Edwards Lifesciences
- Location
- Irvine, CA + 44 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)
DiaMedica Therapeutics Inc
- Location
- Arcadia, CA + 35 other US sites
- Eligibility basics
- Ages 18–90
- RecruitingPhase 3
Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)
AbbVie
- Location
- Anaheim, CA + 87 other US sites
- Eligibility basics
- Ages 6–17
- RecruitingPhase 2
A Study of LBP-EC01 in the Treatment of Acute Uncomplicated UTI Caused by Drug Resistant E. Coli (ELIMINATE Trial)
Locus Biosciences
- Location
- Lancaster, CA + 11 other US sites
- Eligibility basics
- Ages 18–75 · Women only