Location · California
Clinical trials recruiting in California
1900 recruiting studies have at least one site in California; 700 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,900 recruiting studiesSource: ClinicalTrials.gov, refreshed October 27, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 3
A Phase 3 Study of Rezpegaldesleukin (NKTR-358) for Patients ≥ 12 Years of Age With Moderate-to-Severe Atopic Dermatitis
Nektar Therapeutics
- Location
- Oxnard, CA + 12 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 1/Phase 2
Study Assessing CLENPIQ as Bowel Preparation for Pediatric Colonoscopy
Ferring Pharmaceuticals
- Location
- San Diego, CA + 3 other US sites
- Eligibility basics
- Ages 1–8
- RecruitingPhase 4
A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice…
Eli Lilly and Company
- Location
- Fountain Valley, CA + 38 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research Design
Axsome Therapeutics, Inc.
- Location
- Anaheim, CA + 48 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Chronic Low Back Pain
Eli Lilly and Company
- Location
- Riverside, CA + 31 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Osteoarthritis Pain
Eli Lilly and Company
- Location
- Palm Springs, CA + 35 other US sites
- Eligibility basics
- Ages 40+
- RecruitingPhase 3
Study of d-MAPPS™ Ophthalmic Solution in Adults With Chronic Ocular Graft-Versus-Host Disease (oGVHD)
Regenerative Ocular Immunobiologics LLC
- Location
- Beverly Hills, CA + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular Degeneration
Astellas Institute for Regenerative Medicine
- Location
- Los Angeles, CA + 12 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 1
Safety and Feasibility Study of the CELLSPAN Esophageal Implant (CEI) in Patients Requiring Short Segment Esophageal Replacement
Harvard Apparatus Regenerative Technology, Inc.
- Location
- Los Angeles, CA + 2 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
A Study to Find Out How Nusinersen is Processed in the Body When Given Through the ThecaFlex DRx™ System in Adult and Pediatric Participants With Spinal Muscular Atrophy (PIERRE-PK)
Biogen
- Location
- Orange, CA + 11 other US sites
- Eligibility basics
- Ages 3+
- RecruitingPhase 1/Phase 2
Dose Escalation Study of EG110A, Administered by Intradetrusor Injections to Adults With Neurogenic Detrusor Overactivity-related Incontinence Following Spinal Cord Injury Who Regularly Perform Clean Intermittent…
Cyllene Therapeutics
- Location
- Downey, CA + 3 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)
AstraZeneca
- Location
- Garden Grove, CA + 53 other US sites
- Eligibility basics
- Ages 40–80
- RecruitingPhase 3
A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis
Bristol-Myers Squibb
- Location
- Fremont, CA + 26 other US sites
- Eligibility basics
- Ages 12–17
- RecruitingPhase 2
Phase 2 Study of ADX-038 in Participants With Geographic Atrophy
ADARx Pharmaceuticals, Inc.
- Location
- Bakersfield, CA + 18 other US sites
- Eligibility basics
- Ages 60+
- RecruitingPhase 1
OM336 in Autoimmune Cytopenias
Lakefront Biotherapeutics West LLC
- Location
- Duarte, CA + 3 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Cumberland Pharmaceuticals
- Location
- San Francisco, CA + 17 other US sites
- Eligibility basics
- Ages 40+
- RecruitingPhase 1
A Study of VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease
Verve Therapeutics, Inc.
- Location
- Pomona, CA + 9 other US sites
- Eligibility basics
- Ages 18–70
- Recruiting
The SetPoint System as a Pro-Remyelination Therapy for Relapsing-Remitting Multiple Sclerosis: A Pilot Study
SetPoint Medical Corporation
- Location
- Irvine, CA + 8 other US sites
- Eligibility basics
- Ages 22–60
- RecruitingPhase 1
A Study to Evaluate the Safety, Tolerability, and PK of an Injectable Form of KarXT
Bristol-Myers Squibb
- Location
- Los Alamitos, CA + 7 other US sites
- Eligibility basics
- Ages 18–55
- Recruiting
Pivotal Study of the Velocity™ pAVF System
Venova Medical
- Location
- Concord, CA + 12 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kidney Injury.
AstraZeneca
- Location
- Newport Beach, CA + 7 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
Donidalorsen Treatment in Children With Hereditary Angioedema
Ionis Pharmaceuticals, Inc.
- Location
- Santa Monica, CA + 7 other US sites
- Eligibility basics
- Ages 2–11
- RecruitingPhase 2
A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD
Pulmovant, Inc.
- Location
- Santa Barbara, CA + 12 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 3
An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)
Inhibikase Therapeutics
- Location
- Beverly Hills, CA + 14 other US sites
- Eligibility basics
- Ages 18–75