Location · California
Clinical trials recruiting in California
1900 recruiting studies have at least one site in California; 700 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,900 recruiting studiesSource: ClinicalTrials.gov, refreshed October 27, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 2
Phase 2a Dose Finding Study of Nu-3 Gel in Subjects With Mild iDFU
Lakewood-Amedex Inc
- Location
- Los Angeles, CA + 5 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin
AstraZeneca
- Location
- Sacramento, CA + 6 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Phase 1 Study Evaluating Safety and Pharmacokinetics of ASY202 in Adults With Asthma
Aspeya, Inc.
- Location
- Anaheim, CA
- Eligibility basics
- Ages 18–55
- RecruitingPhase 1/Phase 2
FT839 in Autoimmune Diseases
Fate Therapeutics
- Location
- Fullerton, CA
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes
Vertex Pharmaceuticals Incorporated
- Location
- Duarte, CA + 9 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
Usnoflast Neuromuscular Investigation for Treatment Efficacy in Amyotrophic Lateral Sclerosis
Zydus Therapeutics Inc.
- Location
- La Jolla, CA + 13 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
A Prospective, Randomized, Single-blind, Controlled, Multi-center Study to Assess the Safety and Performance of MagnetOsTM Compared to Autogenous Bone Graft in Patients Undergoing Hindfoot or Ankle Fusions.
Kuros Biosurgery AG
- Location
- Sacramento, CA + 6 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and…
Novo Nordisk A/S
- Location
- Lancaster, CA + 55 other US sites
- Eligibility basics
- Ages 45+
- RecruitingPhase 2/Phase 3
Open Label, Safety and Efficacy Study of QRX003 Lotion in Subjects With Netherton Syndrome
Quoin Pharmaceuticals
- Location
- San Diego, CA + 2 other US sites
- Eligibility basics
- Ages 14+
- RecruitingPhase 1/Phase 2
Study of CTO1681 for the Prevention and Treatment of CRS in Patients Receiving CAR T-Cell Therapy
CytoAgents, Inc.
- Location
- Orange, CA + 5 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Post Approval Study of Liposorber LA-15 System for the Treatment of Focal Segmental Glomerulosclerosis in Children
Kaneka Medical America LLC
- Location
- Loma Linda, CA + 9 other US sites
- Eligibility basics
- Up to age 21
- Recruiting
Post Approval Study for Treatment of Drug-resistant Adult and Pediatric Primary FSGS Using the LIPOSORBER® LA-15 System
Kaneka Medical America LLC
- Location
- Loma Linda, CA + 9 other US sites
- Eligibility basics
- Up to age 75
- RecruitingPhase 2/Phase 3
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
Merck Sharp & Dohme LLC
- Location
- Los Angeles, CA + 19 other US sites
- Eligibility basics
- Ages 1 mo–17
- RecruitingPhase 1/Phase 2
ALXN2350 in Adult Participants With BAG3-Associated Dilated Cardiomyopathy
Alexion Pharmaceuticals, Inc.
- Location
- Palo Alto, CA + 6 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 2/Phase 3
A Clinical Study Evaluating Licaminlimab for Dry Eye Disease
Oculis
- Location
- Aliso Viejo, CA + 11 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Phase 2b Study of the Effects of Camoteskimab in Adults With Moderate-to-Severe Atopic Dermatitis
Apollo Therapeutics Ltd
- Location
- Huntington Beach, CA + 24 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
Efficacy and Safety of CSL222 (Etranacogene Dezaparvovec) Gene Therapy in Adults With Hemophilia B With Pretreatment Adeno-associated Virus Serotype 5 (AAV5) Neutralizing Antibodies (Nabs)
CSL Behring
- Location
- San Diego, CA + 3 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
The Golazo® Peripheral Atherectomy System for a Safe and Effective Atherectomy (GREAT Trial)
Nipro Vascular Innovations Americas, Inc
- Location
- Merced, CA + 16 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
Cytokinetics
- Location
- Imperial, CA + 23 other US sites
- Eligibility basics
- Ages 40–85
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Study Participants With Palmoplantar Pustulosis
UCB Biopharma SRL
- Location
- Fremont, CA + 7 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Narcolepsy
Harmony Biosciences Management, Inc.
- Location
- Los Angeles, CA + 26 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
MTX-001 for the Treatment of Non-Healing Venous Stasis Ulcers
Merakris Therapeutics
- Location
- Castro Valley, CA + 9 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Microcurrent Stimulation Therapy for Intermediate to Advanced Nonexudative Age-related Macular Degeneration
i-Lumen Scientific AUS PTY LTD
- Location
- Poway, CA + 5 other US sites
- Eligibility basics
- Ages 60+
- RecruitingPhase 2
A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia
R1 Therapeutics
- Location
- Chula Vista, CA + 23 other US sites
- Eligibility basics
- Ages 18+