Location · California
Clinical trials recruiting in California
1900 recruiting studies have at least one site in California; 700 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,900 recruiting studiesSource: ClinicalTrials.gov, refreshed October 27, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 3
Efficacy and Safety of Novosis Putty in Transforaminal Lumbar Interbody Fusion for Patients With Lumbar Degenerative Disc Disease
CGBio Inc.
- Location
- Sacramento, CA + 7 other US sites
- Eligibility basics
- Ages 21–80
- Recruiting
CAPTURE-2: Controlled Arterial Protection to Ultimately Remove Embolic Material
EmStop Inc
- Location
- Thousand Oaks, CA + 6 other US sites
- Eligibility basics
- Ages 22+
- RecruitingPhase 1/Phase 2
Evaluation of Intra-articular CX-011 to Treat Moderate to Severe Pain From Knee Osteoarthritis
CarthroniX, Inc.
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 40–75
- RecruitingPhase 2
Study to Evaluate Resmetirom in Post-Liver Transplant Patients With MASH
Madrigal Pharmaceuticals, Inc.
- Location
- La Jolla, CA + 11 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
Procyrion
- Location
- Concord, CA + 31 other US sites
- Eligibility basics
- Ages 21+
- RecruitingPhase 3
A Study of Pitolisant in Patients With Prader-Willi Syndrome
Harmony Biosciences Management, Inc.
- Location
- Los Angeles, CA + 18 other US sites
- Eligibility basics
- Ages 6+
- RecruitingPhase 2
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease
Immunovant Sciences GmbH
- Location
- Huntington Beach, CA + 54 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Phase 2 Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation (The ReInspire Study)
Relay Therapeutics, Inc.
- Location
- Los Angeles, CA + 21 other US sites
- Eligibility basics
- Ages 2+
- RecruitingPhase 2
A Study to Assess Safety and Tolerability of PCRX-201 in Subjects With Painful Osteoarthritis of the Knee
Pacira Pharmaceuticals, Inc
- Location
- Huntington Beach, CA + 2 other US sites
- Eligibility basics
- Ages 45–80
- RecruitingPhase 2
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease
Immunovant Sciences GmbH
- Location
- Concord, CA + 32 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants Undergoing Open Abdominal Ventral Hernia Repair
AbbVie
- Location
- Riverside, CA + 10 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 1
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4954 in Healthy Adult Participants With or Without Elevated Lipoprotein (a) (Lp[a]) Levels, and Participants With Dyslipidemia
AstraZeneca
- Location
- Glendale, CA + 5 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event
AstraZeneca
- Location
- Beverly Hills, CA + 206 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Robotic-Enabled Microsurgical Intervention for Neurodegenerative Disease
MMI (Medical Microinstruments, Inc.)
- Location
- Palo Alto, CA + 2 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
A Phase III Study to Evaluate the Efficacy and Safety of Libevitug in Participants With Chronic HDV Infection (D-clear Study)
Huahui Health
- Location
- Garden Grove, CA
- Eligibility basics
- Ages 12–70
- RecruitingPhase 1/Phase 2
4D-150 in Patients With Neovascular (Wet) Age-Related Macular Degeneration
4D Molecular Therapeutics
- Location
- Oxnard, CA + 19 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 1/Phase 2
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne
Sanofi Pasteur, a Sanofi Company
- Location
- Cerritos, CA + 78 other US sites
- Eligibility basics
- Ages 18–45
- RecruitingPhase 2
Safety and Efficacy of 3 Dose Levels of NMD670 in Adult Patients With Myasthenia Gravis
NMD Pharma A/S
- Location
- Irvine, CA + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
Amgen
- Location
- Beverly Hills, CA + 193 other US sites
- Eligibility basics
- Ages 50–105
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Tabirafusp Tedromer Compared to Aflibercept in Participants With DME - ALTO
Kodiak Sciences Inc
- Location
- Glendale, CA + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
Kallyope Inc.
- Location
- Colton, CA + 111 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy
Alcyone Therapeutics, Inc
- Location
- Orange, CA + 14 other US sites
- Eligibility basics
- Ages 3+
- RecruitingPhase 1/Phase 2
AAV Gene Therapy Clinical Study in Adult Classic PKU (PHEdom)
NGGT INC.
- Location
- Orange, CA + 4 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingPhase 3
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
Novo Nordisk A/S
- Location
- Alhambra, CA + 129 other US sites
- Eligibility basics
- Ages 18+