Location · California
Clinical trials recruiting in California
1900 recruiting studies have at least one site in California; 700 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,900 recruiting studiesSource: ClinicalTrials.gov, refreshed October 27, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 3
Study to Evaluate the Efficacy and Safety of Ponesimod (VSP-128) in Patients With Moderately to Severely Active Ulcerative Colitis
Vanda Pharmaceuticals
- Location
- Chula Vista, CA + 1 other US site
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- Location
- Orange, CA + 7 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 1
A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of DNL952 in Adult Participants With Late-Onset Pompe Disease
Denali Therapeutics Inc.
- Location
- Irvine, CA + 3 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
A Study of Amicidin-β Topical Solution for Patients With Surgical or Traumatic Wound Infections
Macro Biologics, Inc.
- Location
- Torrance, CA + 4 other US sites
- Eligibility basics
- Ages 18–79
- RecruitingPhase 2
Descartes-08 in Autoantibody Myositis
Cartesian Therapeutics
- Location
- Orange, CA + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and Adolescents With at Risk Type 2 Asthma
GlaxoSmithKline
- Location
- Newport Beach, CA + 13 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 3
AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
Novo Nordisk A/S
- Location
- Escondido, CA + 17 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Phase 1 Study of C.001 in Retinal Degeneration
Cellio Therapeutics Inc
- Location
- Beverly Hills, CA
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Study to Evaluate Weight Gain as Assessed by Change in BMI Z-score in Pediatric Subjects With Schizophrenia or Bipolar I Disorder
Alkermes, Inc.
- Location
- Stanford, CA + 14 other US sites
- Eligibility basics
- Ages 10–17
- Recruiting
Alleviant ALLAY-HF Study
Alleviant Medical, Inc.
- Location
- Long Beach, CA + 42 other US sites
- Eligibility basics
- Ages 40+
- RecruitingPhase 2
A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder
AbbVie
- Location
- Anaheim, CA + 32 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
Study of DONQ52 in Active Celiac Disease
Chugai Pharmaceutical
- Location
- Escondido, CA + 57 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2/Phase 3
Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer's Disease Dementia
Exciva GmbH
- Location
- Murrieta, CA + 6 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 3
Study of Lenacapavir, Teropavimab, and Zinlirvimab Versus Cabotegravir and Rilpivirine in Virologically Suppressed Adults With HIV-1 on Oral Daily Antiretroviral Therapy
Gilead Sciences
- Location
- San Francisco, CA + 15 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Limbal Stem Cell Deficiency
Claris Biotherapeutics, Inc.
- Location
- Loma Linda, CA + 5 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Phase II, Placebo Controlled, Clinical Trial of Topical TolaSure Targeting Aggregated Mutant Keratin in Epidermolysis Bullosa Simplex
BioMendics, LLC
- Location
- Palo Alto, CA + 1 other US site
- Eligibility basics
- Ages 2+
- RecruitingPhase 2
INHALE-1st: Afrezza® For Youth With Newly-Diagnosed Type 1 Diabetes
Mannkind Corporation
- Location
- Los Angeles, CA + 9 other US sites
- Eligibility basics
- Ages 6–17
- RecruitingPhase 4
Rifaximin 200 mg Plus Oral Rehydration vs Oral Rehydration Alone in Children With Acute Diarrhea
Bausch Health Americas, Inc.
- Location
- Lynwood, CA + 9 other US sites
- Eligibility basics
- Ages 6–12
- RecruitingPhase 4
Obtaining Descriptive Classifications of Pruritus and Assessing Change in Pruritus Over Time in Atopic Dermatitis Patients Using Topical Roflumilast Cream.
Integrative Skin Science and Research
- Location
- Sacramento, CA
- Eligibility basics
- Ages 12+
- Recruiting
This Study Aims to Evaluate Whether Milamend's Product Could Improve Hormone Balance in Women Who Suffer From Self-reported PCOS Symptoms.
Mila Mend Inc.
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 18–40 · Women only
- RecruitingPhase 2
A Study to Evaluate the Efficacy and Safety of IMG-007 in Adult Participants With Moderate-to-Severe Atopic Dermatitis
Inmagene LLC
- Location
- Lancaster, CA + 15 other US sites
- Eligibility basics
- Ages 18–74
- RecruitingPhase 2
A Study to Assess the Effectiveness and Safety of GSK3862995B in Adults With Bronchiectasis
GlaxoSmithKline
- Location
- La Palma, CA + 29 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 3
NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Neurocrine Biosciences
- Location
- Glendale, CA + 11 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
A Prospective Multicenter Clinical Investigation Evaluating the Accuracy of the Trimline Design When Treated With SureSmile® Aligners.
Dentsply Sirona Implants and Consumables
- Location
- Fresno, CA + 2 other US sites
- Eligibility basics
- Ages 18+