Location · California
Clinical trials recruiting in California
1900 recruiting studies have at least one site in California; 700 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,900 recruiting studiesSource: ClinicalTrials.gov, refreshed October 27, 2026How we list studies
More recruiting studies (pay not posted)
- Recruiting
Post-market Surveillance Study of the BD® WavelinQ™ EndoAVF System
C. R. Bard
- Location
- La Jolla, CA + 13 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Early Feasibility Study of "HyperQureTM RDN System", Laparoscopic Renal Denervation Therapy, in Patients With Resistant Hypertension
DeepQure Inc.
- Location
- Orange, CA + 5 other US sites
- Eligibility basics
- Ages 22–80
- RecruitingPhase 3
NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Neurocrine Biosciences
- Location
- Chino, CA + 9 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Reduction or Elimination of Mitral Regurgitation With the SATURN TMVR System (CASSINI-US)
InnovHeart
- Location
- Thousand Oaks, CA + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)
Nkarta, Inc.
- Location
- Orange, CA + 14 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)
Eli Lilly and Company
- Location
- Los Angeles, CA + 39 other US sites
- Eligibility basics
- Ages 10–17
- RecruitingPhase 1
A Study of ABBV-295 Subcutaneous Injections to Assess Adverse Events and Pharmacokinetics in Adult Participants With Obesity
AbbVie
- Location
- Anaheim, CA + 1 other US site
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1/Phase 2
A Study With NVC-001 in Patients With LMNA-related Dilated Cardiomyopathy (SUNBEAM-LMNA)
Nuevocor Pte. Ltd.
- Location
- Los Angeles, CA + 2 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections
X4 Pharmaceuticals
- Location
- Irvine, CA + 20 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 2
A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis
Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA
- Location
- Los Angeles, CA + 27 other US sites
- Eligibility basics
- Ages 18–80
- Recruiting
BOOM-IBD2 Pivotal Clinical Trial
Boomerang Medical
- Location
- Folsom, CA + 15 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 3
Evaluation of the Safety and Effectiveness of ARTIA Reconstructive Tissue Matrix Breast Reconstruction (ADORA) in Adult Participants
AbbVie
- Location
- Los Angeles, CA + 14 other US sites
- Eligibility basics
- Ages 18+ · Women only
- RecruitingPhase 2/Phase 3
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)
EyeBiotech Ltd.
- Location
- Encino, CA + 51 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2
A Phase 2b Dose-Ranging Study to Evaluate the Efficacy and Safety of ENV-294 in Adults With Moderate-to-Severe Atopic Dermatitis
Enveda Therapeutics
- Location
- Encinitas, CA + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Trial of CRD-4730 in HFrEF
Cardurion Pharmaceuticals, Inc.
- Location
- Pasadena, CA + 1 other US site
- Eligibility basics
- Ages 18–85
- RecruitingPhase 3
Study to Evaluate Safety and Efficacy of Different PANZYGA Dose Regimens in Pediatric Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) Patients
Octapharma
- Location
- Orange, CA + 5 other US sites
- Eligibility basics
- Ages 2–17
- RecruitingPhase 3
Study to Evaluate ARINA-1 in the Prevention of Bronchiolitis Obliterans Progression in Participants With Bilateral Lung Transplant
Renovion, Inc.
- Location
- Los Angeles, CA + 17 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1/Phase 2
A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants, Adolescents and Adults With Hearing Loss Due to Otoferlin Mutations
Regeneron Pharmaceuticals
- Location
- Los Angeles, CA + 8 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 2
A Study to Evaluate the Safety and Efficacy of a Single Dose of RABI-767 in Participants With Acute Pancreatitis
Panafina, Inc.
- Location
- Los Angeles, CA + 9 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 2
Safety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD)
CSL Behring
- Location
- Orange, CA + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
IS-001 Injection in Patients Undergoing Robotic-Assisted Colorectal Surgery
Intuitive Surgical
- Location
- Newport Beach, CA + 5 other US sites
- Eligibility basics
- Ages 16–75
- RecruitingPhase 2
Ixoberogene Soroparvovec (Ixo-vec) Contralateral Dosing Study in Participants With Neovascular Age-related Macular Degeneration
Adverum Biotechnologies, Inc.
- Location
- Bakersfield, CA + 11 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
Eidos Therapeutics, a BridgeBio company
- Location
- La Jolla, CA + 39 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease
BlueRock Therapeutics
- Location
- Los Angeles, CA + 33 other US sites
- Eligibility basics
- Ages 45–75