Location · California
Clinical trials recruiting in California
1900 recruiting studies have at least one site in California; 700 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,900 recruiting studiesSource: ClinicalTrials.gov, refreshed October 27, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 3
A Study of TAK-330 to Reverse the Effects of Factor Xa Inhibitors For Adults Needing Urgent Surgery
Takeda
- Location
- Sacramento, CA + 12 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Global Trial in APG2575 for Patients With CLL/SLL
Ascentage Pharma Group Inc.
- Location
- Anaheim, CA + 10 other US sites
- Eligibility basics
- Ages 18–99
- RecruitingEarly Phase 1
VTP-1000 in Adults With Celiac Disease
Barinthus Biotherapeutics
- Location
- Los Angeles, CA + 15 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
A Study to Evaluate Safety and Effectiveness of NOA VOLUME Injectable Gel in Adult Participants Compared to JUVÉDERM VOLUMA XC for Improvement of Mid-Face Volume
AbbVie
- Location
- San Diego, CA + 14 other US sites
- Eligibility basics
- Ages 22+
- RecruitingPhase 3
Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Ravulizumab Administered Intravenously in Adult Participants at High Risk of Delayed Graft Function After Kidney…
Alexion Pharmaceuticals, Inc.
- Location
- Los Angeles, CA + 28 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Study of ALXN1920 in Adult Participants With Primary Membranous Nephropathy (PMN)
Alexion Pharmaceuticals, Inc.
- Location
- Loma Linda, CA + 4 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
Efficacy and Safety Study of TPX-115 on Partial-thickness Rotator Cuff Tear
Tego Science, Inc.
- Location
- La Mesa, CA + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder
AbbVie
- Location
- Anaheim, CA + 46 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
A Study of Axatilimab at 3 Different Doses in Participants With Chronic Graft Versus Host Disease (cGVHD)
Syndax Pharmaceuticals
- Location
- Los Angeles, CA + 12 other US sites
- Eligibility basics
- Ages 2+
- Recruiting
Evaluation of Enhanced Lithotripsy System (ELS) in the Treatment of Urinary Stones, A Pivotal Trial
Avvio Medical
- Location
- La Mesa, CA + 11 other US sites
- Eligibility basics
- Ages 21+
- RecruitingPhase 2
Evaluate Efficacy and Safety of Repeat Subcutaneous Doses of FB825 in Adults With Moderate-to-Severe Atopic Dermatitis
Oneness Biotech Co., Ltd.
- Location
- Fountain Valley, CA + 5 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
A Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcaprant in Adult Participants With Major Depressive Disorder
AbbVie
- Location
- Anaheim, CA + 32 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1
R-3750 in Patients With Mild to Moderate Ulcerative Colitis
Rise Therapeutics LLC
- Location
- Valencia, CA + 4 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1
R-2487 in Patients With Rheumatoid Arthritis
Rise Therapeutics LLC
- Location
- San Diego, CA + 5 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
The THOR IDE Study
Philips Clinical & Medical Affairs Global
- Location
- St. Helena, CA + 28 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
A Clinical Study to Evaluate the Safety and Efficacy of the FloStent in Men With Benign Prostatic Hyperplasia Symptoms
Rivermark Medical
- Location
- Bakersfield, CA + 18 other US sites
- Eligibility basics
- Ages 45+ · Men only
- Recruiting
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
Abbott Medical Devices
- Location
- Sacramento, CA + 56 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))
Neurona Therapeutics
- Location
- Los Angeles, CA + 34 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
A Study of Efimosfermin Alfa in Adults With Hepatic Impairment
GlaxoSmithKline
- Location
- Rialto, CA + 2 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 1/Phase 2
A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT1988 in Participants at Clinical High Risk for Psychosis
Monument Therapeutics Limited
- Location
- Irvine, CA + 14 other US sites
- Eligibility basics
- Ages 17–30
- RecruitingPhase 3
Evaluating the Effects of Tasimelteon vs. Placebo in Treating Pediatric Insomnia
Vanda Pharmaceuticals
- Location
- Irvine, CA + 18 other US sites
- Eligibility basics
- Ages 2–17
- RecruitingPhase 2
Phase 2 Study to Evaluate EI-001 in Non-segmental Vitiligo Patients
Elixiron Immunotherapeutics (Hong Kong) Ltd.
- Location
- Huntington Beach, CA + 3 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1/Phase 2
A Phase 1/2 Study of NKX019 in Subjects With Autoimmune Disease (Ntrust-1)
Nkarta, Inc.
- Location
- Tustin, CA + 15 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults
Ardelyx
- Location
- Canoga Park, CA + 108 other US sites
- Eligibility basics
- Ages 18–80