Location · California
Clinical trials recruiting in California
1900 recruiting studies have at least one site in California; 700 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,900 recruiting studiesSource: ClinicalTrials.gov, refreshed October 27, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 2
Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns
Skingenix, Inc.
- Location
- Sacramento, CA + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study Comparing KB803 and Matched Placebo in Patients With Dystrophic Epidermolysis Bullosa
Krystal Biotech, Inc.
- Location
- Rancho Santa Margarita, CA + 4 other US sites
- Eligibility basics
- Ages 6 mo+
- RecruitingPhase 2/Phase 3
Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare
Olatec Therapeutics, Inc.
- Location
- San Diego, CA + 15 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 4
A Study to Evaluate the Clinical Outcomes of Efgartigimod PH20 SC in Adults With New-onset Generalized Myasthenia Gravis (gMG)
argenx
- Location
- La Jolla, CA + 17 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
EvaluatioN of Optilume Drug-Coated Balloon for the Endoscopic Treatment of UREteric Strictures
Urotronic Inc.
- Location
- Orange, CA + 6 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
NBI-1117568-SCZ3029: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia
Neurocrine Biosciences
- Location
- Anaheim, CA + 20 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
A Study of Zasocitinib in Adults With Hidradenitis Suppurativa
Takeda
- Location
- Fountain Valley, CA + 4 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions
Takeda
- Location
- Redwood City, CA + 18 other US sites
- Eligibility basics
- Ages 16–70
- RecruitingPhase 3
Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)
Takeda
- Location
- La Jolla, CA + 19 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
Study to Evaluate Soquelitinib in Participants With Moderate to Severe AD
Corvus Pharmaceuticals, Inc.
- Location
- South San Francisco, CA
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of ALD-102 Solution in Subjects With Alopecia Areata
Aldena Therapeutics
- Location
- Thousand Oaks, CA + 3 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingPhase 2
A Study to Evaluate Efficacy and Safety of Light Dose in Subjects With PWB Treated With Hemoporfin PDT
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.
- Location
- Irvine, CA + 4 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Trial of Etelcalcetide in Pediatric Participants With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis
Amgen
- Location
- Los Angeles, CA + 4 other US sites
- Eligibility basics
- Ages 0 mo–18
- RecruitingPhase 2
A Clinical Trial Evaluating the Efficacy and Safety of Leflutrozole on Testicular Function
ReproNovo Aps
- Location
- North Hollywood, CA + 3 other US sites
- Eligibility basics
- Ages 18–49 · Men only
- RecruitingPhase 1/Phase 2
A Study Comparing KB801 Verse Placebo in Patients With Stage 2 or 3 Neurotrophic Keratitis
Krystal Biotech, Inc.
- Location
- Pasadena, CA + 6 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension
Vanda Pharmaceuticals
- Location
- Chula Vista, CA + 17 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
Evaluation of the Safety and Efficacy of GLK-321 in Subjects With Demodex Blepharitis
Glaukos Corporation
- Location
- Newport Beach, CA
- Eligibility basics
- Ages 18+
- Recruiting
A Randomized, Triple-blind, Placebo-controlled Study to Evaluate the Effects of a Supplement on Nutrient Gaps and Gut Health Among Individuals Utilizing GLP-1 RAs
Athletic Greens International
- Location
- Santa Monica, CA
- Eligibility basics
- Ages 18–59
- RecruitingPhase 3
Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS)
Direct Biologics, LLC
- Location
- Davis, CA + 30 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2/Phase 3
Trial to Visualize the Ureters With Nizaracianine Triflutate in Adults Undergoing Abdominopelvic Surgery
Curadel Surgical Innovations, Inc.
- Location
- Los Angeles, CA + 4 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Silicone Gel vs. Estrogen Vaginal Cream for the Management of Genitourinary Syndrome of Menopause
Stratpharma AG
- Location
- Laguna Hills, CA + 2 other US sites
- Eligibility basics
- Ages 18+ · Women only
- Recruiting
VALOR: Vaginal Atrophy & Long-term Observation of Recovery
Stratpharma AG
- Location
- Burbank, CA + 5 other US sites
- Eligibility basics
- Ages 18+ · Women only
- RecruitingPhase 3
52 Week Study + 24-Month Long-Term Extension of Safety, PK, & Efficacy of XYOSTED® for Testosterone Replacement in Male Adolescents With Hypogonadism
Halozyme Therapeutics
- Location
- Los Angeles, CA + 19 other US sites
- Eligibility basics
- Ages 12–17 · Men only
- Recruiting
Trial to Evaluate the Safety and Effectiveness of Treatment With COMS One Device in Subjects With Diabetic Foot Ulcers
Piomic Medical
- Location
- Castro Valley, CA + 24 other US sites
- Eligibility basics
- Ages 22–90