Location · North Carolina
Clinical trials recruiting in North Carolina
857 recruiting studies have at least one site in North Carolina; 250 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in North Carolina.
857 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
Efficacy, Safety, and Tolerability of Zeleciment Basivarsen (DYNE-101) in Participants With Myotonic Dystrophy Type 1
Dyne Therapeutics
- Location
- Hillsborough, NC + 13 other US sites
- Eligibility basics
- Ages 16+
- RecruitingPhase 3
A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitis
Janssen Research & Development, LLC
- Location
- Chapel Hill, NC + 23 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Safety and Effectiveness of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere VT)
Medtronic Cardiac Ablation Solutions
- Location
- Winston-Salem, NC + 4 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 3
A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
Pfizer
- Location
- Greensboro, NC + 29 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Two Arm, Double-blind, Phase III Study Assessing Efficacy and Safety of Ianalumab Versus Placebo, in Participants With Sjögren's Disease With High Symptom Burden
Novartis Pharmaceuticals
- Location
- Charlotte, NC + 19 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
An Extension Study to Assess Safety and Efficacy of Remibrutinib in Participants With Moderate to Severe HS
Novartis Pharmaceuticals
- Location
- Huntersville, NC + 20 other US sites
- Eligibility basics
- Ages 18–100
- RecruitingPhase 3
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
AstraZeneca
- Location
- Greensboro, NC + 43 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Idiopathic Pulmonary Fibrosis (IPF)-Related Chronic Cough Reduction With Nalbuphine Extended-Release (NAL ER) Tablets
Trevi Therapeutics
- Location
- Gastonia, NC + 21 other US sites
- Eligibility basics
- Ages 40+
- Recruiting
The Artisse™ Intrasaccular Device is Indicated for the Treatment of Wide-neck Bifurcating Intracranial Aneurysms (IAs).
Medtronic Neurovascular Clinical Affairs
- Location
- Charlotte, NC + 24 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
An Efficacy and Safety Study of Clemizole HCl in Patients With Lennox-Gastaut Syndrome
Epygenix
- Location
- Charlotte, NC + 16 other US sites
- Eligibility basics
- Ages 2–55
- RecruitingPhase 2/Phase 3
Alpelisib in Pediatric and Adult Patients With Lymphatic Malformations Associated With a PIK3CA Mutation.
Novartis Pharmaceuticals
- Location
- Chapel Hill, NC + 17 other US sites
- Eligibility basics
- Ages 0 mo–100
- RecruitingPhase 1
A Phase 1 Study of LY5830966 in Participants With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I…
Ajax Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company
- Location
- Charlotte, NC + 12 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease
Incyte Corporation
- Location
- Winston-Salem, NC + 36 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 2/Phase 3
A Long-Term Study of ALKS 2680 in Subjects With Narcolepsy and Idiopathic Hypersomnia
Alkermes, Inc.
- Location
- Denver, NC + 32 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib
Incyte Corporation
- Location
- Chapel Hill, NC + 73 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)
AstraZeneca
- Location
- Charlotte, NC + 53 other US sites
- Eligibility basics
- Ages 40–80
- RecruitingPhase 2
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
Eli Lilly and Company
- Location
- Morehead City, NC + 24 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension
Tempus AI
- Location
- Winston-Salem, NC + 39 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
EPIK-P4: A Phase II Single-arm Study to Assess the Efficacy, Safety and Pharmacokinetics of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum (PROS)
Novartis Pharmaceuticals
- Location
- Chapel Hill, NC + 8 other US sites
- Eligibility basics
- Ages 2–100
- RecruitingPhase 2
A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256)
Incyte Corporation
- Location
- Charlotte, NC + 6 other US sites
- Eligibility basics
- Ages 2–17
- RecruitingPhase 2
An Extension Trial to Test if TEV-56286 is Effective in Relieving Multiple System Atrophy
Teva Branded Pharmaceutical Products R&D LLC
- Location
- Durham, NC + 9 other US sites
- Eligibility basics
- Ages 30+
- Recruiting
AtraUmatic Laparoscopic HerNia Repair Clinical Investigation to Evaluate the Safety and Performance of The ECLIPSIUM System for Mesh Fixation IDE
Tissium
- Location
- Durham, NC + 7 other US sites
- Eligibility basics
- Ages 22+
- RecruitingPhase 2
A Study of a Thyroid Hormone Receptor Beta Isoform (THRβ) Agonist and an Semicarbazide Sensitive Amine Oxidase (SSAO) Inhibitor, Alone and in Combination, in Adults With Presumed Metabolic Dysfunction-associated…
Eccogene
- Location
- Fayetteville, NC + 65 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
Parasternal Extravascular ICD System Pivotal Clinical Investigation (ALARION EV) Study
AtaCor Medical, Inc.
- Location
- Charlotte, NC + 11 other US sites
- Eligibility basics
- Ages 18+