Location · North Carolina
Clinical trials recruiting in North Carolina
857 recruiting studies have at least one site in North Carolina; 250 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in North Carolina.
857 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
A Study to Evaluate the Pharmacokinetics and Safety of XEMBIFY Versus Gamunex-C in Participants With Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Grifols Therapeutics LLC
- Location
- Fayetteville, NC + 7 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Study Evaluating the Efficacy, Safety, and Tolerability of ASY202 (Dihydroergotamine Mesylate [DHE] Inhalation Powder Delivered Via a Multidose Dry Powder Inhaler) for the Acute Treatment of Migraine in Adult Patients
Aspeya, Inc.
- Location
- Raleigh, NC + 19 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
Idiopathic Pulmonary Fibrosis (IPF)-Related Chronic Cough Reduction With Nalbuphine (NAL) Extended-Release (ER) Tablets
Trevi Therapeutics
- Location
- Charlotte, NC + 3 other US sites
- Eligibility basics
- Ages 40+
- Recruiting
A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease
W.L.Gore & Associates
- Location
- Charlotte, NC + 20 other US sites
- Eligibility basics
- Ages 18–90
- RecruitingPhase 3
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
Xenon Pharmaceuticals Inc.
- Location
- Charlotte, NC + 44 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 3
A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)
Xenon Pharmaceuticals Inc.
- Location
- Durham, NC + 14 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease
Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)
- Location
- Fayetteville, NC + 22 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 3
Pegtibatinase as a Treatment for Participants With Classical Homocystinuria (HCU) Receiving Standard of Care Treatment
Travere Therapeutics, Inc.
- Location
- Morrisville, NC + 11 other US sites
- Eligibility basics
- Ages 12–65
- RecruitingPhase 2
Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis
CSL Behring
- Location
- Greenville, NC + 18 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 2
A Study of TAK-360 in Adults With Narcolepsy Without Cataplexy (NT2)
Takeda
- Location
- Denver, NC + 24 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 2
A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis
AbbVie
- Location
- Charlotte, NC + 48 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease
Bristol-Myers Squibb
- Location
- Morehead City, NC + 21 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 3
REGN7508 Versus Apixaban and Enoxaparin for Thromboprophylaxis After Total Knee Arthroplasty in Adults
Regeneron Pharmaceuticals
- Location
- Durham, NC + 17 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
Amgen
- Location
- Charlotte, NC + 136 other US sites
- Eligibility basics
- Ages 45–99
- RecruitingPhase 3
TRITON-PN: A Study to Evaluate the Efficacy and Safety of Nucresiran in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy
Alnylam Pharmaceuticals
- Location
- Chapel Hill, NC + 9 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 2
Study to Assess the Effects of ALN-ANG3 in Adult Participants With Diabetic Kidney Disease
Regeneron Pharmaceuticals
- Location
- Greenville, NC + 55 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
Eli Lilly and Company
- Location
- Greensboro, NC + 59 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Closed-Loop Transcranial Alternating Current Stimulation for the Treatment of Major Depressive Disorder
Pulvinar Neuro, LLC
- Location
- Durham, NC
- Eligibility basics
- Ages 22+
- RecruitingPhase 2
A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy
argenx
- Location
- Hillsborough, NC + 10 other US sites
- Eligibility basics
- Ages 5–17
- RecruitingPhase 2
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
Eli Lilly and Company
- Location
- Greenville, NC + 38 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight
Eli Lilly and Company
- Location
- Greensboro, NC + 39 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study Evaluating the Efficacy and Safety of Xywav Expanded Dosing vs Placebo in Participants With Narcolepsy or IH
Jazz Pharmaceuticals
- Location
- Denver, NC + 14 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation
Regeneron Pharmaceuticals
- Location
- Concord, NC + 43 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity
Eli Lilly and Company
- Location
- Greensboro, NC + 68 other US sites
- Eligibility basics
- Ages 18+