Location · North Carolina
Clinical trials recruiting in North Carolina
857 recruiting studies have at least one site in North Carolina; 250 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in North Carolina.
857 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingHealthy volunteers
Safety and Effectiveness of the Yaari Extractor for Management of Shoulder Dystocia
FetalEase Ltd.
- Location
- Winston-Salem, NC + 3 other US sites
- Eligibility basics
- Ages 18+ · Women only
- RecruitingHealthy volunteers
Aimovig Pregnancy Exposure Registry
Amgen
- Location
- Durham, NC
- Eligibility basics
- Ages 18–99 · Women only
- RecruitingHealthy volunteers
Pilot Study for Colorectal Cancer and Advanced Adenoma Detection With the Mainz Biomed Colorectal Cancer Test
Mainz Biomed
- Location
- Morrisville, NC
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Registry of Arthrex Hand and Wrist Products
Arthrex, Inc.
- Location
- Durham, NC + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Outcomes Following Combined Adductoplasty™ and Lapiplasty® (MTA3D)
Treace Medical Concepts, Inc.
- Location
- Morrisville, NC + 8 other US sites
- Eligibility basics
- Ages 14–65
- RecruitingHealthy volunteers
Treatment to Lift Facial Lax Skin and Improve Facial Wrinkles Using Precise and Lift Applicators
Sofwave Medical LTD
- Location
- Durham, NC + 1 other US site
- Eligibility basics
- Ages 35–80
- RecruitingHealthy volunteers
Project Mountain - Comparing SpO2 and SaO2 for Accuracy
Philips Clinical & Medical Affairs Global
- Location
- Durham, NC + 4 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 1/Phase 2
A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome
Encoded Therapeutics
- Location
- Durham, NC + 9 other US sites
- Eligibility basics
- Ages 6 mo–17
- RecruitingPhase 3
Study to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of a Modified Regimen of Ublituximab
TG Therapeutics, Inc.
- Location
- Charlotte, NC + 35 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)
Hoffmann-La Roche
- Location
- Charlotte, NC + 121 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH
Hoffmann-La Roche
- Location
- Asheville, NC + 112 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)
Merck Sharp & Dohme LLC
- Location
- Chapel Hill, NC + 70 other US sites
- Eligibility basics
- Ages 16–80
- RecruitingPhase 1
A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease
CRISPR Therapeutics
- Location
- Chapel Hill, NC + 7 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
A Study of Mezagitamab in Adults With Kidney Condition Called IgA Nephropathy
Takeda
- Location
- Winston-Salem, NC + 42 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
AstraZeneca
- Location
- New Bern, NC + 58 other US sites
- Eligibility basics
- Ages 40+
- Recruiting
GORE® TAG® Thoracic Branch Endoprosthesis Zone 0/1 Post-Approval Study
W.L.Gore & Associates
- Location
- Chapel Hill, NC + 21 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype
Sanofi
- Location
- Greenville, NC + 70 other US sites
- Eligibility basics
- Ages 40–80
- RecruitingPhase 2
A Study to Learn About the Effects of Felzartamab Infusions in Adults With Kidney Transplants Who Have Late Isolated Microvascular Inflammation
Biogen
- Location
- Durham, NC + 24 other US sites
- Eligibility basics
- Ages 18–74
- RecruitingPhase 3
Trial to Evaluate the Efficacy and Safety of LYT-100 (Deupirfenidone) Compared to Pirfenidone in Adults With Idiopathic Pulmonary Fibrosis (IPF)
PureTech
- Location
- Greensboro, NC + 15 other US sites
- Eligibility basics
- Ages 40+
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Veverimer for the Treatment of Metabolic Acidosis
Renibus Therapeutics, Inc.
- Location
- Winston-Salem, NC + 26 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Trial to Evaluate the Safety, Tolerability and Efficacy of AIC263029 in Kidney Transplant Recipients With BKV Infection
AiCuris Anti-infective Cures AG
- Location
- Winston-Salem, NC + 6 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)
Amgen
- Location
- Morehead City, NC + 51 other US sites
- Eligibility basics
- Ages 18–99
- RecruitingPhase 2
A Clinical Trial of MK-7262 and Enlicitide in Participants With High Lipoprotein(a) (MK-7262-004)
Merck Sharp & Dohme LLC
- Location
- Durham, NC + 23 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study of WIN378 in Participants With Moderate to Severe COPD (Sirius)
Windward Bio
- Location
- Charlotte, NC + 8 other US sites
- Eligibility basics
- Ages 40–80