Location · North Carolina
Clinical trials recruiting in North Carolina
857 recruiting studies have at least one site in North Carolina; 250 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in North Carolina.
857 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
A Study to Investigate Canvuparatide Compared With Placebo in Adult Patients With Hypoparathyroidism
MBX Biosciences
- Location
- Greenville, NC + 19 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-004)
Merck Sharp & Dohme LLC
- Location
- Wake Forest, NC + 27 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-005)
Merck Sharp & Dohme LLC
- Location
- Greenville, NC + 18 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Phase 3 Study of Denifanstat in Participants With Moderate to Severe Acne (AURORA)
Sagimet Biosciences Inc.
- Location
- Wilmington, NC + 17 other US sites
- Eligibility basics
- Ages 12+
- Recruiting
Neutrophil and Monocyte Deactivation Via the SeLective CytopheretIc Device - A Randomized Clinical Trial in Acute Kidney Injury
SeaStar Medical
- Location
- Chapel Hill, NC + 23 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell…
Incyte Corporation
- Location
- Chapel Hill, NC + 29 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Migalastat in Pediatric Subjects (2 to <12 Yrs) With Fabry Disease and Amenable GLA Variants
Amicus Therapeutics
- Location
- Charlotte, NC + 5 other US sites
- Eligibility basics
- Ages 2–11
- RecruitingPhase 2
A Long-term Safety and Efficacy Study Evaluating APG777 in Atopic Dermatitis
Apogee Therapeutics, Inc.
- Location
- Wilmington, NC + 22 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Virtue® SAB in the Treatment of Coronary ISR Trial
Orchestra BioMed, Inc
- Location
- Asheville, NC + 21 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study Investigating Intravenous Human Normal Immunoglobulin 10% in Adults With Chronic Immune Thrombocytopenia (ITP)
Kedrion S.p.A.
- Location
- Greenville, NC + 2 other US sites
- Eligibility basics
- Ages 18–70
- Recruiting
Diagnosing Epilepsy To EffeCT Change
Epiminder America, Inc.
- Location
- Charlotte, NC + 21 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study to Evaluate the Maintenance Effect of Osavampator as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Neurocrine Biosciences
- Location
- Charlotte, NC + 19 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
REGN7508 Versus Acetylsalicylic Acid (ASA) for Venous Thromboprophylaxis After Total Knee Arthroplasty in Adult Participants
Regeneron Pharmaceuticals
- Location
- Charlotte, NC + 35 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
Evaluation of PLG0206 in Prevention of Recurrent Infection in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Following Knee Arthroplasty
Peptilogics
- Location
- Leland, NC + 13 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 3
A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-1)
Generate Biomedicines
- Location
- Gastonia, NC + 35 other US sites
- Eligibility basics
- Ages 12–80
- RecruitingPhase 2
A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia
Vima Therapeutics
- Location
- Fayetteville, NC + 36 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
Reducing Adverse Vascular Outcomes With Factor XI Inhibition in Adult Participants With Peripheral Artery Disease
Regeneron Pharmaceuticals
- Location
- Charlotte, NC + 26 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease
Pfizer
- Location
- Winston-Salem, NC + 58 other US sites
- Eligibility basics
- Ages 35–80
- RecruitingPhase 2
An Exploratory Efficacy and Safety Study of DFL24498 Topical Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease
Dompé Farmaceutici S.p.A
- Location
- Garner, NC + 12 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Trial Comparing the Safety and Efficacy of Two Different Oral VPV Doses With Placebo as Treatment for RV in Participants With COPD
Altesa Biosciences, Inc.
- Location
- Kings Mountain, NC + 28 other US sites
- Eligibility basics
- Ages 40–85
- RecruitingPhase 3
A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus
AstraZeneca
- Location
- Morehead City, NC + 12 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants With Upper Limb Essential Tremor
AbbVie
- Location
- Winston-Salem, NC + 17 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 2
A Study to Learn About The Effects of Felzartamab on Thyroid Function and Its Safety in Adults With Graves' Disease Ages 18 to 75 Years Old
Biogen
- Location
- Asheville, NC + 10 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
- Location
- Chapel Hill, NC + 19 other US sites
- Eligibility basics
- Ages 18+