Location · North Carolina
Clinical trials recruiting in North Carolina
857 recruiting studies have at least one site in North Carolina; 250 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in North Carolina.
857 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- Recruiting
Prevail Global Study
Medtronic Vascular
- Location
- Greensboro, NC + 53 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Efficacy and Safety of VER-01 in the Treatment of Participants With Chronic Painful Lumbosacral Radiculopathy
Vertanical GmbH
- Location
- Monroe, NC + 22 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
A Study of Brepocitinib in Adults With Cutaneous Sarcoidosis
Priovant Therapeutics, Inc.
- Location
- Chapel Hill, NC + 34 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation
Regeneron Pharmaceuticals
- Location
- Greensboro, NC + 41 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease
Sanofi
- Location
- Chapel Hill, NC + 33 other US sites
- Eligibility basics
- Ages 16–80
- RecruitingPhase 3
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
Novo Nordisk A/S
- Location
- Durham, NC + 58 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus (RSV) Who Are at High Risk of Progression to Severe Disease
Shionogi
- Location
- Winston-Salem, NC + 35 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Study to Evaluate Safety of C-1101 Versus Sterile Saline in Adults With Chronic Painful Lumbosacral Radiculopathy
Consano Bio
- Location
- Winston-Salem, NC + 1 other US site
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
Sarilumab Efficacy and Safety in Adults With Early Polymyalgia Rheumatica
Sanofi
- Location
- Charlotte, NC + 46 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2
Confirmatory Clinical Study in Active Ulcerative Colitis
MRM Health NV
- Location
- Fayetteville, NC + 5 other US sites
- Eligibility basics
- Ages 16+
- RecruitingPhase 3
Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures FOCUS-1
Rapport Therapeutics Inc.
- Location
- Asheville, NC + 13 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Phase 3 Study of Rezpegaldesleukin (NKTR-358) for Patients ≥ 12 Years of Age With Moderate-to-Severe Atopic Dermatitis
Nektar Therapeutics
- Location
- Wilmington, NC + 18 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 4
A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting
Takeda
- Location
- Charlotte, NC + 77 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)
Merck Sharp & Dohme LLC
- Location
- Charlotte, NC + 54 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
SPYRAL GEMINI Pilot Study
Medtronic Vascular
- Location
- Chapel Hill, NC + 11 other US sites
- Eligibility basics
- Ages 18–80
- Recruiting
AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions
Boston Scientific Corporation
- Location
- Charlotte, NC + 46 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)
Merck Sharp & Dohme LLC
- Location
- Matthews, NC + 34 other US sites
- Eligibility basics
- Ages 50–85
- RecruitingPhase 3
TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy
Alnylam Pharmaceuticals
- Location
- Charlotte, NC + 40 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 4
A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.
Sanofi
- Location
- Charlotte, NC + 10 other US sites
- Eligibility basics
- Ages 40–85
- RecruitingPhase 3
A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis
Zenas BioPharma (USA), LLC
- Location
- Raleigh, NC + 18 other US sites
- Eligibility basics
- Ages 18–60
- RecruitingPhase 3
A Phase 3 Randomized Clinical Trial to Investigate the Safety and Efficacy of Palopegteriparatide at Doses Greater Than 30 μg/Day in Adult Participants With Hypoparathyroidism
Ascendis Pharma Bone Diseases A/S
- Location
- Greenville, NC + 7 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A 52-week Study of Rilzabrutinib Efficacy and Safety Compared to Placebo in Adults Diagnosed With IgG4-related Disease
Sanofi
- Location
- Charlotte, NC + 20 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Dose-masked Study of Intravitreal Remigromig (EYE103) in Participants With NVAMD or Macular Edema Following BRVO
EyeBiotech Ltd.
- Location
- Asheville, NC + 54 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Safety and Efficacy Study of a One-time Intravitreal Injection of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration
Sanofi
- Location
- Wake Forest, NC + 30 other US sites
- Eligibility basics
- Ages 60+