Location · North Carolina
Clinical trials recruiting in North Carolina
857 recruiting studies have at least one site in North Carolina; 250 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in North Carolina.
857 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis
Medipost, Inc.
- Location
- Charlotte, NC + 33 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
Post Approval Effectiveness and Durability Evaluation of the Altaviva™ Tibial Device
MedtronicNeuro
- Location
- Greensboro, NC + 18 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Mellitus Who Are Not Achieving Glycemic Targets While Using GLP-1-Based Therapy
Biomea Fusion Inc.
- Location
- Morehead City, NC + 19 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
BEACON - Phase III Clinical Study of Rugonersen in Angelman Syndrome.
OHB Pediatrics Ltd.
- Location
- Chapel Hill, NC + 4 other US sites
- Eligibility basics
- Ages 1–50
- RecruitingPhase 2
Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis
AbbVie
- Location
- Asheville, NC + 60 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities
AbbVie
- Location
- Greensboro, NC + 58 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Study to Assess Linsitinib in Participants With Moderate to Severe Active Thyroid Eye Disease (TED)
Sling Therapeutics, Inc.
- Location
- Asheville, NC + 16 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
CHAMPION: A Study to Evaluate the Efficacy and Safety of Obudanersen (ION582) in Children and Adults With Angelman Syndrome (AS)
Ionis Pharmaceuticals, Inc.
- Location
- Carrboro, NC
- Eligibility basics
- Ages 2–50
- Recruiting
MagnetOs Flex Matrix Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion
Kuros Biosurgery AG
- Location
- Pinehurst, NC + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis.
Basilea Pharmaceutica
- Location
- Chapel Hill, NC + 21 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Strategy for Improving Stroke Treatment Response
Translational Sciences, Inc.
- Location
- Durham, NC + 37 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Test the Efficacy and Safety of Riliprubart Against the Usual Treatment of Intravenous Immunoglobulin (IVIg) in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Sanofi
- Location
- Raleigh, NC + 31 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Evaluate the Efficacy and Safety of Frexalimab, Brivekimig, or Rilzabrutinib in Participants Aged 16 to 75 Years With Primary Focal Segmental Glomerulosclerosis or Minimal Change Disease
Sanofi
- Location
- Chapel Hill, NC + 16 other US sites
- Eligibility basics
- Ages 16–75
- RecruitingPhase 3
An Open Label Clinical Study to Evaluate Tanruprubart (Also Commonly Known as ANX005) in Participants With Guillain-Barré Syndrome (FORWARD Study)
Annexon, Inc.
- Location
- Durham, NC + 19 other US sites
- Eligibility basics
- Ages 8–85
- RecruitingPhase 3
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
Hoffmann-La Roche
- Location
- Greensboro, NC + 67 other US sites
- Eligibility basics
- Ages 50–90
- RecruitingPhase 3
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype
Sanofi
- Location
- Durham, NC + 72 other US sites
- Eligibility basics
- Ages 40–80
- Recruiting
Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI)
Supira Medical
- Location
- Asheville, NC + 24 other US sites
- Eligibility basics
- Ages 18–90
- RecruitingPhase 3
A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT
SymBio Pharmaceuticals
- Location
- Durham, NC + 24 other US sites
- Eligibility basics
- Ages 2 mo+
- RecruitingPhase 3
A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With…
Amgen
- Location
- Charlotte, NC + 73 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Phase 3 Study of Telitacicept in Active Primary Sjögren's Disease
Vor Biopharma
- Location
- Charlotte, NC + 46 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
Study to Evaluate HM15275 in Subjects With Type 2 Diabetes Mellitus
Hanmi Pharmaceutical Company Limited
- Location
- Morehead City, NC + 19 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events
Novo Nordisk A/S
- Location
- Monroe, NC + 9 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Study of AZD2389 Safety, Tolerability, and Pharmacodynamics in Adults With Steatotic Liver Disease and Advanced Fibrosis
AstraZeneca
- Location
- Morehead City, NC + 17 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Study to Determine if BHV-1300 is Effective and Safe in Adults With Graves' Disease
Biohaven Therapeutics Ltd.
- Location
- Asheville, NC + 52 other US sites
- Eligibility basics
- Ages 18–70