Location · North Carolina
Clinical trials recruiting in North Carolina
857 recruiting studies have at least one site in North Carolina; 250 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in North Carolina.
857 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- Location
- Matthews, NC + 56 other US sites
- Eligibility basics
- Ages 55–90
- Recruiting
Maturation of Arteriovenous Fistula With Automated Sonography Assessments Trial
Sonavex, Inc.
- Location
- Concord, NC + 19 other US sites
- Eligibility basics
- Ages 18–84
- RecruitingPhase 2/Phase 3
RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic Sclerosis
Cabaletta Bio
- Location
- Durham, NC + 9 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
Hoffmann-La Roche
- Location
- Charlotte, NC + 91 other US sites
- Eligibility basics
- Ages 16–80
- RecruitingPhase 3
A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)
Bristol-Myers Squibb
- Location
- Morehead City, NC + 10 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 2
A Study to Test Whether BI 1815368 Helps People With an Eye Condition Called Diabetic Macular Edema
Boehringer Ingelheim
- Location
- Wake Forest, NC + 21 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Phase 2 Study of LTI-03 in Patients With Idiopathic Pulmonary Fibrosis
Rein Therapeutics
- Location
- Chapel Hill, NC + 19 other US sites
- Eligibility basics
- Ages 40+
- Recruiting
BIOTRONIK Investigation of the LivIQ Leadless Pacemaker System
Biotronik, Inc.
- Location
- Charlotte, NC + 23 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
Sanofi
- Location
- Fayetteville, NC + 36 other US sites
- Eligibility basics
- Ages 16–80
- RecruitingPhase 3
Evaluation of IV AMBTX-01 (Neridronate) for Treatment of CRPS Type 1 (CRPS-RISE)
Ambros Therapeutics, Inc.
- Location
- Charlotte, NC + 29 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Elite AF IDE Trial (Elite AF)
Boston Scientific Corporation
- Location
- Charlotte, NC + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
ACX-362E [Ibezapolstat] for Oral Treatment of Recurrent Clostridioides Difficile Infection
Acurx Pharmaceuticals Inc.
- Location
- Winston-Salem, NC + 10 other US sites
- Eligibility basics
- Ages 18–90
- RecruitingPhase 3
A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC PFS in Adult Participants With Graves' Disease
argenx
- Location
- Asheville, NC + 26 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
NORM-HF Pivotal Study
Foundry Innovation & Research 1, Limited (FIRE1)
- Location
- Chapel Hill, NC + 22 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
An Investigation of FID 123472 Ophthalmic Solution to Vehicle for the Reduction of Ocular Redness in Adults
Alcon Research
- Location
- Garner, NC + 2 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Pridopidine Phase 3 Study in Huntington's Disease
Prilenia
- Location
- Durham, NC + 8 other US sites
- Eligibility basics
- Ages 23–65
- RecruitingPhase 3
A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine
Kallyope Inc.
- Location
- Charlotte, NC + 111 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory Myopathy
Cabaletta Bio
- Location
- Chapel Hill, NC + 29 other US sites
- Eligibility basics
- Ages 6–75
- RecruitingPhase 3
A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)
Novartis Pharmaceuticals
- Location
- Greenville, NC + 16 other US sites
- Eligibility basics
- Ages 12–100
- Recruiting
Infant Formula in Infants and Children With Cow's Milk Allergy
Abbott Nutrition
- Location
- Chapel Hill, NC + 7 other US sites
- Eligibility basics
- Ages 4 mo–12
- RecruitingPhase 2
A Study to Learn About the Study Medicine Aztreonam-Avibactam (ATM-AVI) in Infants and Newborns Admitted in Hospitals With Bacterial Infection (CHERISH)
Pfizer
- Location
- Durham, NC + 10 other US sites
- Eligibility basics
- Up to age 10 mo
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus
UCB Biopharma SRL
- Location
- Charlotte, NC + 61 other US sites
- Eligibility basics
- Ages 16+
- RecruitingPhase 3
Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy
Vertex Pharmaceuticals Incorporated
- Location
- Morehead City, NC + 57 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 1
A Study to Learn About How Changing Therapy From Emicizumab to Marstacimab Affects People With the Severe Hemophilia A.
Pfizer
- Location
- Greenville, NC + 2 other US sites
- Eligibility basics
- Ages 12–74 · Men only