Location · North Carolina
Clinical trials recruiting in North Carolina
857 recruiting studies have at least one site in North Carolina; 250 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in North Carolina.
857 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
A Study to Evaluate the Safety and Efficacy of MK-1406/CD388 for Prevention of Influenza (MK-1406-005/CD388.SQ.3.06)
Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
- Location
- Wilmington, NC + 51 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 3
A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc Disease
DiscGenics, Inc.
- Location
- Wilmington, NC + 29 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)
Bausch Health Americas, Inc.
- Location
- Charlotte, NC + 36 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Effect of FB301 on Vaginal Bacterial Profile in Women With Asymptomatic Vaginal Dysbiosis Undergoing a Mock Frozen Embryo Transfer Cycle
Freya Biosciences ApS
- Location
- Charlotte, NC + 2 other US sites
- Eligibility basics
- Ages 18–45 · Women only
- RecruitingPhase 3
Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures
Rapport Therapeutics Inc.
- Location
- Raleigh, NC + 12 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Study of GS-3242 in Combination With Lenacapavir Versus Biktarvy in Virologically Suppressed People With HIV-1
Gilead Sciences
- Location
- Huntersville, NC + 40 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Study to Assess the Effect and Safety of ALV-100 on Maintenance of Weight Loss
Alveus Therapeutics, Inc.
- Location
- Wilmington, NC + 19 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette);
Genentech, Inc.
- Location
- Durham, NC + 14 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Boehringer Ingelheim
- Location
- Greensboro, NC + 91 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis
Boehringer Ingelheim
- Location
- Fayetteville, NC + 123 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have Not Taken Biologic Medicines
Takeda
- Location
- Hickory, NC + 45 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
Boehringer Ingelheim
- Location
- Lenoir, NC + 78 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised
Pfizer
- Location
- Durham, NC + 68 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
OPI-NXYDLD-303 Safety and Efficacy of Phentolamine Ophthalmic Solution in Keratorefractive Surgery Participants With Decreased Mesopic Visual Acuity
Opus Genetics, Inc
- Location
- Garner, NC + 19 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Brivekimig for the Treatment of Moderate to Severe Hidradenitis Suppurativa
Sanofi
- Location
- Chapel Hill, NC + 16 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Find Out if BI 764198 Helps Adults and Adolescents With a Kidney Condition Called Focal Segmental Glomerulosclerosis (FSGS)
Boehringer Ingelheim
- Location
- Greensboro, NC + 55 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 3
A Gaucher Disease Gene Therapy Trial With FLT201
Spur Therapeutics
- Location
- Durham, NC + 12 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Test Whether BI 3802876 is Tolerated in People With Compensated Liver Cirrhosis Due to Metabolic Dysfunction- Associated Steatohepatitis (MASH)
Boehringer Ingelheim
- Location
- Morehead City, NC + 18 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE)
Boehringer Ingelheim
- Location
- Fayetteville, NC + 15 other US sites
- Eligibility basics
- Ages 18–74
- RecruitingPhase 3
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable
Regeneron Pharmaceuticals
- Location
- Concord, NC + 42 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated
Boehringer Ingelheim
- Location
- Wake Forest, NC + 24 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's Disease
Janssen Research & Development, LLC
- Location
- Chapel Hill, NC + 21 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 4
A Study to Learn About the Safety of Taking an Additional Dose of the Medicine Rimegepant in Adults With Migraine
Pfizer
- Location
- Greensboro, NC + 16 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration
Amgen
- Location
- Raleigh, NC + 54 other US sites
- Eligibility basics
- Ages 50+