Location · Tennessee
Clinical trials recruiting in Tennessee
515 recruiting studies have at least one site in Tennessee; 118 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in Tennessee.
515 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- Recruiting
AtraUmatic Laparoscopic HerNia Repair Clinical Investigation to Evaluate the Safety and Performance of The ECLIPSIUM System for Mesh Fixation IDE
Tissium
- Location
- Knoxville, TN + 7 other US sites
- Eligibility basics
- Ages 22+
- RecruitingPhase 1
A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME)
Genentech, Inc.
- Location
- Germantown, TN + 11 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate the Pharmacokinetics and Safety of XEMBIFY Versus Gamunex-C in Participants With Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Grifols Therapeutics LLC
- Location
- Cordova, TN + 7 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Study Evaluating the Efficacy, Safety, and Tolerability of ASY202 (Dihydroergotamine Mesylate [DHE] Inhalation Powder Delivered Via a Multidose Dry Powder Inhaler) for the Acute Treatment of Migraine in Adult Patients
Aspeya, Inc.
- Location
- Memphis, TN + 19 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)
Xenon Pharmaceuticals Inc.
- Location
- Nashville, TN + 14 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease
Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)
- Location
- Johnson City, TN + 22 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 1/Phase 2
ATTUNE: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION440 in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome (MDS)
Ionis Pharmaceuticals, Inc.
- Location
- Nashville, TN + 7 other US sites
- Eligibility basics
- Ages 2–65 · Men only
- Recruiting
The PERSEVERE Study
Inari Medical
- Location
- Nashville, TN + 15 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis
AbbVie
- Location
- Jackson, TN + 48 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:
Eli Lilly and Company
- Location
- Cordova, TN + 36 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
TRITON-PN: A Study to Evaluate the Efficacy and Safety of Nucresiran in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy
Alnylam Pharmaceuticals
- Location
- Nashville, TN + 9 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 3
Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease
Eli Lilly and Company
- Location
- Jackson, TN + 27 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
Eli Lilly and Company
- Location
- Jackson, TN + 38 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight
Eli Lilly and Company
- Location
- Nashville, TN + 39 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study Evaluating the Efficacy and Safety of Xywav Expanded Dosing vs Placebo in Participants With Narcolepsy or IH
Jazz Pharmaceuticals
- Location
- Nashville, TN + 14 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation
Regeneron Pharmaceuticals
- Location
- Tullahoma, TN + 43 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity
Eli Lilly and Company
- Location
- Knoxville, TN + 68 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves
Edwards Lifesciences
- Location
- Nashville, TN + 26 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 2
A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight
Eli Lilly and Company
- Location
- Nashville, TN + 42 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
Lighthouse Pharmaceuticals, Inc.
- Location
- Nashville, TN + 36 other US sites
- Eligibility basics
- Ages 55–80
- RecruitingPhase 3
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
Eli Lilly and Company
- Location
- Cordova, TN + 36 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
Eli Lilly and Company
- Location
- Cordova, TN + 34 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 2
Prevention of Recurrent C. Difficile Infection Study With AZD5148 Monoclonal Antibody
AstraZeneca
- Location
- Johnson City, TN + 26 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes
Novo Nordisk A/S
- Location
- Memphis, TN + 20 other US sites
- Eligibility basics
- Ages 18–75