Heart & blood pressure · California
Heart and blood pressure studies in California
162 studies have at least one recruiting site in California. Cardiovascular studies cover high blood pressure, high cholesterol, heart failure, atrial fibrillation and coronary artery disease, among others.
162 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- Recruiting
THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension
SoniVie Inc.
- Location
- Los Angeles, CA + 33 other US sites
- Eligibility basics
- Ages 22–75
- RecruitingPhase 3
Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)
Eli Lilly and Company
- Location
- Beverly Hills, CA + 120 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
To Evaluate the Safety and Efficacy of MANP in Subjects With Difficult to Control/ Resistant Hypertension
E-Star BioTech, LLC
- Location
- Lake Forest, CA + 21 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
A Study to Evaluate Efficacy and Safety of YSBP Compared to Lumigan in Patients With Glaucoma or Ocular Hypertension
YS Life Science Co., Ltd.
- Location
- Newport Beach, CA
- Eligibility basics
- Ages 18+
- Recruiting
Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF
Axon Therapies, Inc.
- Location
- La Jolla, CA + 15 other US sites
- Eligibility basics
- Ages 40+
- RecruitingPhase 2/Phase 3
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
CSL Behring
- Location
- Bakersfield, CA + 147 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
Amgen
- Location
- Beverly Hills, CA + 117 other US sites
- Eligibility basics
- Ages 18–99
- Recruiting
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.
Medtronic Cardiovascular
- Location
- La Jolla, CA + 68 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
A Study of VARIPULSE Pulsed Field Ablation (PFA) Catheter and FARAWAVE PFA Catheter in the Treatment of Participants With Persistent Atrial Fibrillation
Biosense Webster, Inc.
- Location
- Fountain Valley, CA + 9 other US sites
- Eligibility basics
- Ages 18–80
- Recruiting
Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study
Starlight Cardiovascular Inc
- Location
- Los Angeles, CA + 7 other US sites
- Eligibility basics
- Up to age 6 mo
- Recruiting
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
BrioHealth Solutions, Inc.
- Location
- Los Angeles, CA + 46 other US sites
- Eligibility basics
- Ages 18–100
- Recruiting
CellFX® Nanosecond Pulsed Field Ablation (nsPFA)™ Cardiac Surgery Clamp System to Treat Atrial Fibrillation
Pulse Biosciences, Inc.
- Location
- St. Helena, CA + 2 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 2
Study of TX000045 in Participants With Pulmonary Hypertension Due to Interstitial Lung Disease
Tectonic Operating Company, Inc.
- Location
- San Francisco, CA + 1 other US site
- Eligibility basics
- Ages 18–80
- RecruitingPhase 1
A Study of VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease
Verve Therapeutics, Inc.
- Location
- Pomona, CA + 9 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 2
A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD
Pulmovant, Inc.
- Location
- Santa Barbara, CA + 12 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 3
An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)
Inhibikase Therapeutics
- Location
- Beverly Hills, CA + 14 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2/Phase 3
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
Merck Sharp & Dohme LLC
- Location
- Los Angeles, CA + 19 other US sites
- Eligibility basics
- Ages 1 mo–17
- RecruitingPhase 1/Phase 2
ALXN2350 in Adult Participants With BAG3-Associated Dilated Cardiomyopathy
Alexion Pharmaceuticals, Inc.
- Location
- Palo Alto, CA + 6 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 2
AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
Cytokinetics
- Location
- Imperial, CA + 23 other US sites
- Eligibility basics
- Ages 40–85
- Recruiting
CAPTURE-2: Controlled Arterial Protection to Ultimately Remove Embolic Material
EmStop Inc
- Location
- Thousand Oaks, CA + 6 other US sites
- Eligibility basics
- Ages 22+
- Recruiting
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
Procyrion
- Location
- Concord, CA + 31 other US sites
- Eligibility basics
- Ages 21+
- RecruitingPhase 1
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4954 in Healthy Adult Participants With or Without Elevated Lipoprotein (a) (Lp[a]) Levels, and Participants With Dyslipidemia
AstraZeneca
- Location
- Glendale, CA + 5 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event
AstraZeneca
- Location
- Beverly Hills, CA + 206 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
Amgen
- Location
- Beverly Hills, CA + 193 other US sites
- Eligibility basics
- Ages 50–105
Who these studies look for
Many require a diagnosis or specific lab values such as LDL cholesterol or blood pressure readings, and exclude recent heart events.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do heart studies include healthy people?
Some do, especially early-phase studies and those measuring heart effects of new medicines. Check whether a listing says it accepts healthy volunteers.