Heart & blood pressure · California
Heart and blood pressure studies in California
162 studies have at least one recruiting site in California. Cardiovascular studies cover high blood pressure, high cholesterol, heart failure, atrial fibrillation and coronary artery disease, among others.
162 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
Novo Nordisk A/S
- Location
- Alhambra, CA + 129 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Alleviant ALLAY-HF Study
Alleviant Medical, Inc.
- Location
- Long Beach, CA + 42 other US sites
- Eligibility basics
- Ages 40+
- Recruiting
Early Feasibility Study of "HyperQureTM RDN System", Laparoscopic Renal Denervation Therapy, in Patients With Resistant Hypertension
DeepQure Inc.
- Location
- Orange, CA + 5 other US sites
- Eligibility basics
- Ages 22–80
- Recruiting
Reduction or Elimination of Mitral Regurgitation With the SATURN TMVR System (CASSINI-US)
InnovHeart
- Location
- Thousand Oaks, CA + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Study With NVC-001 in Patients With LMNA-related Dilated Cardiomyopathy (SUNBEAM-LMNA)
Nuevocor Pte. Ltd.
- Location
- Los Angeles, CA + 2 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Trial of CRD-4730 in HFrEF
Cardurion Pharmaceuticals, Inc.
- Location
- Pasadena, CA + 1 other US site
- Eligibility basics
- Ages 18–85
- RecruitingPhase 3
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
Eidos Therapeutics, a BridgeBio company
- Location
- La Jolla, CA + 39 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
FORWARD CAD IDE Study
Shockwave Medical, Inc.
- Location
- La Jolla, CA + 27 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Study to Assess the Efficacy and Safety of IMVT-1402 in Participants With Mild to Severe Generalized Myasthenia Gravis
Immunovant Sciences GmbH
- Location
- Carlsbad, CA + 47 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.
Novartis Pharmaceuticals
- Location
- Garden Grove, CA + 18 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Evaluate the Pharmacodynamics of a Combination of QCZ484 and Inclisiran in Participants With Hypertension and Concomitant Hypercholesterolemia
Novartis Pharmaceuticals
- Location
- Lincoln, CA + 26 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals
- Location
- San Francisco, CA + 3 other US sites
- Eligibility basics
- Ages 2–11
- Recruiting
Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions
Teleflex
- Location
- Concord, CA + 9 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
A Pivotal Study to Evaluate the Effectiveness of Isometric Handgrip Therapy in Elevated Blood Pressure and Hypertensive Subjects
Zona Health, Inc
- Location
- Valley Village, CA + 9 other US sites
- Eligibility basics
- Ages 22+
- Recruiting
Coherent Sine Burst Electroporation (CSE) Ablation System US IDE Study for Patients With Atrial Fibrillation
Arga Medtech SA
- Location
- San Diego, CA + 17 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)
Anthos Therapeutics, Inc.
- Location
- Huntington Beach, CA + 131 other US sites
- Eligibility basics
- Ages 65+
- RecruitingPhase 2
A Phase 2 Study of CRD-4730 in CPVT
Cardurion Pharmaceuticals, Inc.
- Location
- San Francisco, CA + 4 other US sites
- Eligibility basics
- Ages 18–99
- Recruiting
Reducing Fluid Overload in Heart Failure Patients Using a Non-invasive, Renal Independent System
AquaPass Medical Ltd.
- Location
- La Jolla, CA + 7 other US sites
- Eligibility basics
- Ages 21–79
- RecruitingPhase 2/Phase 3
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study
Kardigan, Inc.
- Location
- Beverly Hills, CA + 46 other US sites
- Eligibility basics
- Ages 50+
- Recruiting
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
Endotronix, Inc.
- Location
- Los Angeles, CA + 43 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis
Novartis Pharmaceuticals
- Location
- Beverly Hills, CA + 29 other US sites
- Eligibility basics
- Ages 50–80
- RecruitingPhase 3
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS
DalCor Pharmaceuticals
- Location
- Huntington Beach, CA + 112 other US sites
- Eligibility basics
- Ages 45+
- Recruiting
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
Abbott Medical Devices
- Location
- Sacramento, CA + 56 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Applause Study I - Append System Early Feasibility Study
Append Medical Ltd.
- Location
- Los Angeles, CA + 2 other US sites
- Eligibility basics
- Ages 18+
Who these studies look for
Many require a diagnosis or specific lab values such as LDL cholesterol or blood pressure readings, and exclude recent heart events.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do heart studies include healthy people?
Some do, especially early-phase studies and those measuring heart effects of new medicines. Check whether a listing says it accepts healthy volunteers.