Heart & blood pressure · California
Heart and blood pressure studies in California
162 studies have at least one recruiting site in California. Cardiovascular studies cover high blood pressure, high cholesterol, heart failure, atrial fibrillation and coronary artery disease, among others.
162 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 2
A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy
Imbria Pharmaceuticals, Inc.
- Location
- La Jolla, CA + 19 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals
- Location
- San Francisco, CA + 6 other US sites
- Eligibility basics
- Ages 6–11
- RecruitingPhase 2
Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008)
Merck Sharp & Dohme LLC
- Location
- Los Angeles, CA + 8 other US sites
- Eligibility basics
- Ages 1–17
- RecruitingPhase 1
A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)
Rocket Pharmaceuticals Inc.
- Location
- La Jolla, CA + 1 other US site
- Eligibility basics
- Ages 18+
- Recruiting
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
Cardiac Dimensions, Inc.
- Location
- Los Angeles, CA + 50 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)
Intellia Therapeutics
- Location
- Los Angeles, CA + 36 other US sites
- Eligibility basics
- Ages 18–90
- RecruitingPhase 1/Phase 2
Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM
Tenaya Therapeutics
- Location
- La Jolla, CA + 4 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)
XVIVO Perfusion
- Location
- La Jolla, CA + 13 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension
Vanda Pharmaceuticals
- Location
- Chula Vista, CA + 17 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
Focused Orticumab Research for Treating Inflammation in Coronary Arteries
Abcentra
- Location
- Torrance, CA + 4 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR
Edwards Lifesciences
- Location
- Los Angeles, CA + 49 other US sites
- Eligibility basics
- Ages 65+
- RecruitingPhase 2
A Mechanistic Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol
Marea Therapeutics
- Location
- Chula Vista, CA
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2
Mezzion Pharma Co. Ltd
- Location
- Los Angeles, CA + 34 other US sites
- Eligibility basics
- Ages 12–18
- Recruiting
NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness
Endospan Ltd.
- Location
- La Jolla, CA + 23 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System
Aria CV, Inc
- Location
- Los Angeles, CA + 8 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions
Concept Medical Inc.
- Location
- Los Angeles, CA + 23 other US sites
- Eligibility basics
- Ages 18–110
- RecruitingPhase 1
Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC
Tenaya Therapeutics
- Location
- San Francisco, CA + 6 other US sites
- Eligibility basics
- Ages 18–65
- Recruiting
Dehydrated Human Amnion Membrane and Standard of Care Versus Standard of Care Alone in Nonhealing Diabetic Foot Ulcers
Axolotl Biologix
- Location
- Thousand Oaks, CA
- Eligibility basics
- Ages 18+
- Recruiting
PARTNER 3 Trial - Aortic Valve-in-Valve
Edwards Lifesciences
- Location
- Los Angeles, CA + 28 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 1/Phase 2
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction
Sardocor Corp.
- Location
- San Diego, CA + 4 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.
Amneal Pharmaceuticals, LLC
- Location
- Newport Beach, CA + 7 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Promoting Physical Activity and Fitness Among Underserved Latino Families Living in U.S.-Mexico Border Regions
San Diego State University
- Location
- San Diego, CA
- Eligibility basics
- Ages 6+
- RecruitingHealthy volunteers
Gauging Outcomes of Total Milk Ingestion on Lipid and gControl
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets
Northwestern University
- Location
- Sacramento, CA + 3 other US sites
- Eligibility basics
- Ages 30+
Who these studies look for
Many require a diagnosis or specific lab values such as LDL cholesterol or blood pressure readings, and exclude recent heart events.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do heart studies include healthy people?
Some do, especially early-phase studies and those measuring heart effects of new medicines. Check whether a listing says it accepts healthy volunteers.