Healthy volunteers · California
Studies for healthy volunteers in California
701 studies have at least one recruiting site in California. These studies say in their official record that they accept healthy volunteers. Many are Phase 1 studies that test how a new medicine is absorbed and tolerated; others recruit healthy people as a comparison group alongside patients.
701 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingHealthy volunteersPhase 1
A Study to Evaluate the Effect of Food on the Bioavailability of AJ201, and Safety, Tolerability, and Pharmacokinetics of AJ201 in Japanese and White Healthy Male Participants
AnnJi Pharmaceutical Co., Ltd.
- Location
- Los Alamitos, CA
- Eligibility basics
- Ages 18–55 · Men only
- RecruitingHealthy volunteersPhase 1/Phase 2
A Trial to Learn if ALN-PNP is Safe and Well Tolerated in Healthy Adults and Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Regeneron Pharmaceuticals
- Location
- Los Angeles, CA + 4 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1
A First-in-Human Single and Multiple Ascending Dose Study of MT-251
Mirador Therapeutics, Inc.
- Location
- San Diego, CA
- Eligibility basics
- Ages 19–55
- RecruitingHealthy volunteersPhase 1
Evaluate the Pharmacokinetics, Safety, and Tolerability of NSHO-101 in Healthy Participants
Ensho Therapeutics, Inc.
- Location
- Anaheim, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersEarly Phase 1
Single and Multiple Ascending Doses of NTX-253 in Healthy Participants and Participants With Stable Schizophrenia
Neurosterix
- Location
- Los Alamitos, CA
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
A Study to Evaluate the Safety, Tolerability, and Drug Levels of BMS-986521 in Healthy Participants.
Bristol-Myers Squibb
- Location
- Anaheim, CA
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 1
A First-in-Human Single and Multiple Ascending Dose Study of MT-201
Mirador Therapeutics, Inc.
- Location
- San Diego, CA
- Eligibility basics
- Ages 19–55
- RecruitingHealthy volunteersPhase 1/Phase 2
Study of VGA039 in Healthy Volunteers and Patients With Von Willebrand Disease (VIVID)
Vega Therapeutics, Inc
- Location
- Los Angeles, CA + 9 other US sites
- Eligibility basics
- Ages 12–60
- RecruitingHealthy volunteersPhase 1/Phase 2
Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers
Ashvattha Therapeutics, Inc.
- Location
- San Francisco, CA + 2 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 1/Phase 2
Spermatogonial Differentiation Via Testicular Organoid
CellARTs Inc.
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18–60 · Men only
- RecruitingHealthy volunteersPhase 1
A Phase 1 Study to Evaluate Safety, Tolerability and Pharmacokinetics of TIX100 in Healthy Subjects
TIXiMED, Inc.
- Location
- Chula Vista, CA
- Eligibility basics
- Ages 18–70
- RecruitingHealthy volunteersPhase 1/Phase 2
Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions
Thomas Advanced Medical LLC
- Location
- Culver City, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant
City of Hope Medical Center
- Location
- Duarte, CA + 2 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingHealthy volunteersPhase 1
Safety Study of MucoCept-CVN
Craig Cohen, MD, MPH
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18–45 · Women only
- RecruitingHealthy volunteersPhase 1
Writing About Experiences and Health in Older Adults II
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 65+
- RecruitingHealthy volunteersEarly Phase 1
Entire-body PET Scans for Multiple Sclerosis
Brain Health Alliance
- Location
- Ladera Ranch, CA
- Eligibility basics
- Ages 25–55
- RecruitingHealthy volunteersPhase 1
Inflammatory Challenge and Fear
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- San Francisco, CA + 3 other US sites
- Eligibility basics
- Ages 18–60
- RecruitingHealthy volunteersPhase 1
Safety and Tolerability Trial of Psilocybin in Healthy Older Adults
University of Colorado, Denver
- Location
- San Francisco, CA + 5 other US sites
- Eligibility basics
- Ages 65–85
- RecruitingHealthy volunteersEarly Phase 1
Single-tracer Multiparametric PET Imaging
University of California, Davis
- Location
- Sacramento, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
A Study of Psychedelics in Healthy Older Adults With Low Well-being
Jennifer Mitchell
- Location
- San Francisco, CA
- Eligibility basics
- Ages 50–85
- RecruitingHealthy volunteersPhase 1
Evaluation of Oral THC and CBD in Men and Women
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 21–55
- RecruitingHealthy volunteersEarly Phase 1
Randomized Directly Observed Therapy Study to Interpret Clinical Trials of Doxy-PEP
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
High Potency Cannabis: Acute and Protracted Effects
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 21–55
Who these studies look for
“Healthy” is decided at screening, not by you. Sites usually check vital signs, blood and urine tests, an ECG, your medications and sometimes your BMI or smoking status. A study can still turn you away for reasons that have nothing to do with being unwell, such as timing or a full roster.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do healthy volunteer studies pay?
Many do, because volunteers give up time and follow strict schedules, but amounts are set by each study and are usually only confirmed by the research site. When a record states an amount we show the exact wording; otherwise we say compensation is not disclosed.
What happens at a screening visit?
Expect consent paperwork first, then a health questionnaire, vital signs, blood and urine samples and often an ECG. You can ask questions and withdraw at any time, before or after you sign.