Healthy volunteers · California
Studies for healthy volunteers in California
701 studies have at least one recruiting site in California. These studies say in their official record that they accept healthy volunteers. Many are Phase 1 studies that test how a new medicine is absorbed and tolerated; others recruit healthy people as a comparison group alongside patients.
701 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingHealthy volunteersPhase 1
A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1
National Institute of Allergy and Infectious Diseases (NIAID)
- Location
- San Francisco, CA + 4 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 1
Dopamine and Sensorimotor Function in Stuttering
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1/Phase 2
A Phase 1/2A, Randomized Study of a T Follicular Helper (TFH)-Targeting Genetic Vaccine Strategy Designed to Induce Broad, Durable Immune Responses
Kara Chew
- Location
- Los Angeles, CA + 1 other US site
- Eligibility basics
- Ages 40–64
- RecruitingHealthy volunteersPhase 1/Phase 2
Hyperemesis Gravidarum Risk Reduction With Metformin
University of Southern California
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 18–49 · Women only
- RecruitingHealthy volunteersPhase 1
Investigating the Mechanisms of the Effects of Psilocybin on Visual Perception and Visual Representations in the Brain
University of California, Berkeley
- Location
- Berkeley, CA
- Eligibility basics
- Ages 21+
- RecruitingHealthy volunteersPhase 1
COES: Curing Order Effects on Sealants
University of Southern California
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 5–14
- RecruitingHealthy volunteersEarly Phase 1
Brain Mechanisms Supporting Cannabis-induced Pain Relief
University of California, San Diego
- Location
- La Jolla, CA
- Eligibility basics
- Ages 21–65
- RecruitingHealthy volunteersPhase 1
The Effects of Dietary Supplementation on Serum Protein Glycosylation
University of California, Davis
- Location
- Sacramento, CA
- Eligibility basics
- Ages 18–45
- RecruitingHealthy volunteersPhase 1
TREAD: Time Restricted Eating Intervention for Alzheimer's Disease
University of California, San Diego
- Location
- San Diego, CA
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteersEarly Phase 1
Multiparametric [18F]F-AraG Imaging in Post-Acute Sequelae of COVID-19 (PASC)
University of California, Davis
- Location
- Sacramento, CA + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine
University of California, San Francisco
- Location
- San Francisco, CA
- Eligibility basics
- Ages 21–65
- RecruitingHealthy volunteersEarly Phase 1
Cannabis Use, Cognition, and the Endocannabinoid System in HIV
University of California, San Diego
- Location
- San Diego, CA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersEarly Phase 1
Mental Health in Veterans and Families After Group Therapies
Soul Medicine Institute
- Location
- Santa Rosa, CA
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersPhase 1/Phase 2
FACE Phase II (a Stage II Trial)
Stanford University
- Location
- Palo Alto, CA
- Eligibility basics
- Ages 60–89
- RecruitingHealthy volunteersEarly Phase 1
Statin Therapy in Primary Sclerosing Cholangitis (PSC): a Multi-omics Study
Stanford University
- Location
- Stanford, CA
- Eligibility basics
- Ages 18–80
- RecruitingHealthy volunteersEarly Phase 1
CMV-specific HIV-CAR T Cells as Immunotherapy for HIV/AIDS
City of Hope Medical Center
- Location
- Duarte, CA + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 1
Alternation in the Human Microbiome With Commonly Used Topical Medications
University of California, Davis
- Location
- Sacramento, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersEarly Phase 1
Biologic Therapy to Prevent Osteoarthritis After ACL Injury
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 18–35
- RecruitingHealthy volunteersPhase 1
Age-dependent Effects of Smoked and Oral Delta-9-THC
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 18–65
- RecruitingHealthy volunteersPhase 1
A Reduced-Intensity Conditioning Regimen (Cyclophosphamide, Pentostatin, Anti-thymocyte Globulin) Followed by Haploidentical Hematopoietic Stem Cell Transplant for the Treatment of Patients With Refractory or Recurrent…
City of Hope Medical Center
- Location
- Duarte, CA
- Eligibility basics
- Up to age 75
- RecruitingHealthy volunteersPhase 1
PET Imaging Study of 64Cu-GRIP B for Patients Receiving CD19-directed CAR-T Therapy
Michael Randall
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersEarly Phase 1
Precision Dosing of Metformin in Youth With T2D
University of California, San Francisco
- Location
- Oakland, CA + 1 other US site
- Eligibility basics
- Ages 10–21
- RecruitingHealthy volunteersPhase 1
THC and CBD: A Controlled Human Study Probing a Harm Reduction Strategy
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 21–55
- RecruitingHealthy volunteersPhase 1
Delayed Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-matched Kidney Transplants
University of California, Los Angeles
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 18+
Who these studies look for
“Healthy” is decided at screening, not by you. Sites usually check vital signs, blood and urine tests, an ECG, your medications and sometimes your BMI or smoking status. A study can still turn you away for reasons that have nothing to do with being unwell, such as timing or a full roster.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do healthy volunteer studies pay?
Many do, because volunteers give up time and follow strict schedules, but amounts are set by each study and are usually only confirmed by the research site. When a record states an amount we show the exact wording; otherwise we say compensation is not disclosed.
What happens at a screening visit?
Expect consent paperwork first, then a health questionnaire, vital signs, blood and urine samples and often an ECG. You can ask questions and withdraw at any time, before or after you sign.