Healthy volunteers · California
Studies for healthy volunteers in California
701 studies have at least one recruiting site in California. These studies say in their official record that they accept healthy volunteers. Many are Phase 1 studies that test how a new medicine is absorbed and tolerated; others recruit healthy people as a comparison group alongside patients.
701 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingHealthy volunteers
A Prospective Controlled Study to Evaluate the Safety and Effectiveness of Thermage® FLX Radiofrequency Treatment
Bausch Health Americas, Inc.
- Location
- Sacramento, CA + 5 other US sites
- Eligibility basics
- Ages 30–60
- RecruitingHealthy volunteers
Women's Hormonal and Metabolic Wellbeing Study
Daily Nouri
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18–45 · Women only
- RecruitingHealthy volunteers
Detecting Pulmonary Hypertension With the Eko CORE 500 Digital Stethoscope
Eko Devices, Inc.
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 2
A Phase 2 Safety, Tolerability, PK, and Efficacy Study of CS-1103 Following Fentanyl Challenge With Naloxone Blockade
Clear Scientific, Inc.
- Location
- Glendale, CA
- Eligibility basics
- Ages 18–55
- RecruitingHealthy volunteersPhase 2
Caring Recharge Project for Caregivers of Individuals With Alzheimer's Disease
Photozig, Inc.
- Location
- Campbell, CA
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteers
Radicle GI Health RAATM: A Study Assessing the Impact of Health and Wellness Products on Gastrointestinal-Related Quality of Life and Related Health Outcomes
Radicle Science
- Location
- Del Mar, CA
- Eligibility basics
- Ages 21–105
- RecruitingHealthy volunteers
Radicle GI HealthTM VNB: A Study Assessing the Impact of Health and Wellness Products on Constipation and Related Health Outcomes
Radicle Science
- Location
- Del Mar, CA
- Eligibility basics
- Ages 21–105
- RecruitingHealthy volunteers
Comparative Self-collection for Cervical Cancer Screening Pivotal Study
Mel Mont Medical
- Location
- Sherman Oaks, CA + 10 other US sites
- Eligibility basics
- Ages 25–65 · Women only
- RecruitingHealthy volunteers
Shield Post-Approval Study Protocol
Guardant Health, Inc.
- Location
- Anaheim, CA + 48 other US sites
- Eligibility basics
- Ages 45–81
- RecruitingHealthy volunteersPhase 4
A Study to Learn About a COVID-19 Vaccine in Healthy Adults 18 Through 64 Years of Age
BioNTech SE
- Location
- Walnut Creek, CA + 4 other US sites
- Eligibility basics
- Ages 18–64
- RecruitingHealthy volunteers
Intalight Reference Database Protocol for VG200D
Intalight, Inc
- Location
- San Diego, CA + 2 other US sites
- Eligibility basics
- Ages 22+
- RecruitingHealthy volunteers
Establishing Normative Urodynamics Parameters for the Glean Urodynamics System in Healthy Adults
Bright Uro
- Location
- Tustin, CA + 2 other US sites
- Eligibility basics
- Ages 18–45
- RecruitingHealthy volunteers
Motiva Implants® Post-Approval Study
Motiva USA LLC
- Location
- Beverly Hills, CA + 32 other US sites
- Eligibility basics
- Ages 22+ · Women only
- RecruitingHealthy volunteers
Multicenter Trial of Antibiotic Eluting Graft for Promoting New Bone Growth in/Near Infected Bone Cavities
Elute, Inc.
- Location
- Los Angeles, CA + 11 other US sites
- Eligibility basics
- Ages 22+
- RecruitingHealthy volunteers
Philips FAST SpO2 Technology With Masimo Sensors for SpO2 Monitoring in the Neonatal, Infant, and Pediatric Populations
Masimo Corporation
- Location
- Modesto, CA + 1 other US site
- Eligibility basics
- Ages 0 mo–21
- RecruitingHealthy volunteersPhase 3
A Study on the Immune Response and Safety of an Investigational Combined Measles, Mumps, Rubella and Varicella Vaccine, When Administered as Intramuscular Injection to Healthy Children 15 Months to 6 Years of Age
GlaxoSmithKline
- Location
- Walnut Creek, CA + 14 other US sites
- Eligibility basics
- Ages 1–6
- RecruitingHealthy volunteers
EXoPERT EMERALD Clinical Study
EXoPERT
- Location
- Long Beach, CA + 8 other US sites
- Eligibility basics
- Ages 45+
- RecruitingHealthy volunteers
A Study to Evaluate the Effects of a Prebiotic Soda on Glycemic Control in Adults
Olipop, PBC
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 30–70
- RecruitingHealthy volunteers
CREST: Samphire Guided Care Program on Wellbeing, Work Productivity, and Quality of Life
Samphire Group, Inc.
- Location
- San Francisco, CA
- Eligibility basics
- Ages 18–65 · Women only
- RecruitingHealthy volunteers
AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor
Peerbridge Health, Inc
- Location
- Orange, CA + 7 other US sites
- Eligibility basics
- Ages 18+
- RecruitingHealthy volunteersPhase 3
A Study on the Safety of an Investigational Chickenpox Vaccine, When Given to Healthy Children, 12 to 15 Months of Age
GlaxoSmithKline
- Location
- Huntington Park, CA + 14 other US sites
- Eligibility basics
- Ages 1–1
- RecruitingHealthy volunteersPhase 3
A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age
GlaxoSmithKline
- Location
- Canoga Park, CA + 46 other US sites
- Eligibility basics
- Ages 1–1
- RecruitingHealthy volunteersPhase 3
A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine and a Marketed Measles, Mumps and Rubella Vaccine When Administered as Intramuscular Injection to Healthy Children 12 to 15 Months of Age
GlaxoSmithKline
- Location
- Huntington Park, CA + 12 other US sites
- Eligibility basics
- Ages 1–1
- RecruitingHealthy volunteers
Non-invasive Liquid Biopsy Analysis of Epigenomics Signatures in Multiple Cancer Types
ClearNote Health
- Location
- San Diego, CA
- Eligibility basics
- Ages 21–80
Who these studies look for
“Healthy” is decided at screening, not by you. Sites usually check vital signs, blood and urine tests, an ECG, your medications and sometimes your BMI or smoking status. A study can still turn you away for reasons that have nothing to do with being unwell, such as timing or a full roster.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Do healthy volunteer studies pay?
Many do, because volunteers give up time and follow strict schedules, but amounts are set by each study and are usually only confirmed by the research site. When a record states an amount we show the exact wording; otherwise we say compensation is not disclosed.
What happens at a screening visit?
Expect consent paperwork first, then a health questionnaire, vital signs, blood and urine samples and often an ECG. You can ask questions and withdraw at any time, before or after you sign.