Study type
Mental health studies recruiting now
Mental health research includes studies of depression, anxiety, PTSD, bipolar disorder, schizophrenia and ADHD, testing medicines, devices and talk therapies.
520 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
More recruiting studies (pay not posted)
- Recruiting
Mindfulness Training and Respiration Biosignal Feedback - Study 2
Equa Health
- Location
- Pittsburgh, PA
- Eligibility basics
- Ages 18–30
- Recruiting
STEPS - Stress Training and Engagement Via Phone-Based Systems
Equa Health
- Location
- Pittsburgh, PA
- Eligibility basics
- Ages 18–30
- Recruiting
Clinical Outcomes Study of the Nexel Total Elbow
Zimmer Biomet
- Location
- Golden, CO + 3 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study of NTX-1472 in Social Anxiety Disorder
Newleos Therapeutics, Inc.
- Location
- Encino, CA + 9 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)
Bristol-Myers Squibb
- Location
- Gilbert, AZ + 2 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine
Bristol-Myers Squibb
- Location
- Bentonville, AR + 19 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder
AbbVie
- Location
- Huntsville, AL + 46 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
A Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcaprant in Adult Participants With Major Depressive Disorder
AbbVie
- Location
- Dothan, AL + 32 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 1/Phase 2
A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT1988 in Participants at Clinical High Risk for Psychosis
Monument Therapeutics Limited
- Location
- Irvine, CA + 14 other US sites
- Eligibility basics
- Ages 17–30
- RecruitingPhase 2
A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
atai Therapeutics, Inc.
- Location
- Tucson, AZ + 33 other US sites
- Eligibility basics
- Ages 18–65
- Recruiting
The Prism Conformity Trial for Post-Traumatic Stress Disorder in Adolescents
GrayMatters Health Ltd.
- Location
- New York, NY
- Eligibility basics
- Ages 12–21
- Recruiting
Self Neuro-modulation Therapy for Major Depressive Disorder (MDD) With Anhedonia
GrayMatters Health Ltd.
- Location
- Providence, RI + 1 other US site
- Eligibility basics
- Ages 22–75
- RecruitingPhase 2
ALTO-207 in Adults With Treatment-resistant Depression (TRD)
Alto Neuroscience
- Location
- Phoenix, AZ + 11 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
Testing Conversational Agents as a Digital Companion
Friendi.fi Corporation
- Location
- Bloomington, IN + 2 other US sites
- Eligibility basics
- Ages 18–35
- Recruiting
Brain Stimulation for Severe Depression
Inner Cosmos Inc
- Location
- St Louis, MO
- Eligibility basics
- Ages 21–80
- RecruitingPhase 2
Double-blind, Placebo-controlled Study in Adults With Major Depressive Disorder
Supernus Pharmaceuticals, Inc.
- Location
- Garden Grove, CA
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
NBI-1117568-SCZ3029: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia
Neurocrine Biosciences
- Location
- Bryant, AR + 20 other US sites
- Eligibility basics
- Ages 18–65
- Recruiting
A Digitally Assisted Risk Reduction Platform for Youth at High Risk for Suicide
Ksana Health
- Location
- New York, NY
- Eligibility basics
- Ages 13–18
- RecruitingPhase 2
A Clinical Trial to Assess the Efficacy, Safety, and Tolerability of a Repeat Dose of Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety Disorder
VistaGen Therapeutics, Inc.
- Location
- Sherman Oaks, CA + 6 other US sites
- Eligibility basics
- Ages 18–65
- Recruiting
Effectiveness of the SoundHeal Multi-Sensory Integrative Therapy Among Justice-Involved Youth
SoundHeal
- Location
- San Luis Obispo, CA
- Eligibility basics
- Ages 12–18
- RecruitingPhase 2
Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)
Autobahn Therapeutics, Inc.
- Location
- Birmingham, AL + 31 other US sites
- Eligibility basics
- Ages 18–65
- Recruiting
Evaluating the Acceptability, Feasibility and Usability of Various Conversational Data Collection Software
AugMend Health Inc.
- Location
- Cambridge, MA
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Randomized Withdrawal Study in Patients With Schizophrenia
Vanda Pharmaceuticals
- Location
- Rogers, AR + 21 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
Study of ALTO-101 in Patients With Schizophrenia
Alto Neuroscience
- Location
- Garden Grove, CA + 12 other US sites
- Eligibility basics
- Ages 21–55
Who these studies look for
Studies usually require a confirmed diagnosis and stable circumstances, and they monitor safety closely. If you are in crisis, contact a crisis line or emergency services rather than a study.
Matching a page like this one never means you qualify. Each research team decides eligibility at screening.
Questions
Will joining affect my current treatment?
Some studies require changes to medicines, which the study team manages; others add to your usual care. Talk to your own clinician before making any change.