Who can join
Studies for adults 50 and older
These studies set a minimum age of 50 or older in their official record. Many look at conditions more common with age, and some vaccine and memory studies specifically need older participants.
417 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 2
Randomized Study to Evaluate the Effect of Obicetrapib in Participants With Preclinical Alzheimer's Disease
NewAmsterdam Pharma
- Location
- Nashville, TN
- Eligibility basics
- Ages 55–85
- RecruitingPhase 3
Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)
Adverum Biotechnologies, Inc.
- Location
- Mesa, AZ + 78 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2
A Phase IIb Randomized, Multicenter Trial of Subretinal CPCB-RPE1 in Advanced Dry AMD (Geographic Atrophy)
Regenerative Patch Technologies, LLC
- Location
- Huntington Beach, CA + 4 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 1/Phase 2
A Phase 1/2 Study of the Safety and Efficacy of BRX011 Oral Administration Once Daily in Subjects With Geographic Atrophy Secondary to Age-Related Macular Degeneration
Biojiva LLC
- Location
- Gilbert, AZ + 4 other US sites
- Eligibility basics
- Ages 55+
- RecruitingPhase 3
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- Location
- Gilbert, AZ + 43 other US sites
- Eligibility basics
- Ages 55–90
- Recruiting
Safety and Effectiveness of the HIT Reverse HRS
Hip Innovation Technology
- Location
- Miami, FL + 4 other US sites
- Eligibility basics
- Ages 50–75
- RecruitingPhase 2
A Study in Adults With Geographic Atrophy
Sitala Bio LTD
- Location
- Erie, PA + 1 other US site
- Eligibility basics
- Ages 60+
- RecruitingPhase 1/Phase 2
A Study to Assess the Safety and Effects of ABBV-1758 Following Subcutaneous or Intravenous Injections in Participants With Alzheimer's Disease
AbbVie
- Location
- Irvine, CA + 10 other US sites
- Eligibility basics
- Ages 50–90
- Recruiting
Pulsed Electromagnetic Field Treatment In Patients With Alzheimer's Disease
Herrick Medical LLC
- Location
- Hackensack, NJ
- Eligibility basics
- Ages 50–100
- Recruiting
Pulsed Electromagnetic Field Treatment With Dementia Patients
Herrick Medical LLC
- Location
- Boca Raton, FL
- Eligibility basics
- Ages 50–100
- RecruitingPhase 2
A Phase 2 Study of NT-101 Topical in Patients With Wet AMD
NexThera Co., Ltd.
- Location
- Bonita Springs, FL + 2 other US sites
- Eligibility basics
- Ages 50+
- Recruiting
The BRAIN App (Phase 2 SBIR)
Hopeful Aging
- Location
- Winchester, MA
- Eligibility basics
- Ages 65+
- RecruitingPhase 2
Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD
ONL Therapeutics
- Location
- Gilbert, AZ + 55 other US sites
- Eligibility basics
- Ages 55+
- RecruitingPhase 3
Efficacy and Safety of Intranasal Cenegermin in Adult Participants With Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)
Dompé Farmaceutici S.p.A
- Location
- Los Angeles, CA + 13 other US sites
- Eligibility basics
- Ages 50–80
- RecruitingPhase 1
A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular Degeneration
Astellas Institute for Regenerative Medicine
- Location
- Los Angeles, CA + 12 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2
Phase 2 Study of ADX-038 in Participants With Geographic Atrophy
ADARx Pharmaceuticals, Inc.
- Location
- Gilbert, AZ + 18 other US sites
- Eligibility basics
- Ages 60+
- RecruitingPhase 1/Phase 2
Phase I/II Study of SKG0106 Intravitreal Injection in Patients With Neovascular Age-related Macular Degeneration (nAMD)
Skyline Therapeutics (US) Inc.
- Location
- Boston, MA + 2 other US sites
- Eligibility basics
- Ages 50+
- RecruitingEarly Phase 1
Examining the Effects of Theta Burst TMS on Brain Connectivity and Balance Ability in Older Adults With Balance Problems
Weinberg Medical Physics LLC
- Location
- Houston, TX
- Eligibility basics
- Ages 65+
- Recruiting
Microcurrent Stimulation Therapy for Intermediate to Advanced Nonexudative Age-related Macular Degeneration
i-Lumen Scientific AUS PTY LTD
- Location
- Poway, CA + 5 other US sites
- Eligibility basics
- Ages 60+
- RecruitingPhase 1
A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease
Eli Lilly and Company
- Location
- Maitland, FL + 4 other US sites
- Eligibility basics
- Ages 50–85
- Recruiting
Robotic-Enabled Microsurgical Intervention for Neurodegenerative Disease
MMI (Medical Microinstruments, Inc.)
- Location
- Palo Alto, CA + 2 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 1/Phase 2
4D-150 in Patients With Neovascular (Wet) Age-Related Macular Degeneration
4D Molecular Therapeutics
- Location
- Phoenix, AZ + 19 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
Amgen
- Location
- Alexander City, AL + 193 other US sites
- Eligibility basics
- Ages 50–105
- RecruitingPhase 3
Phase 3 Study to Assess Efficacy, Safety & Tolerability of OCU410 For Geographic Atrophy Secondary to Dry AMD
Ocugen
- Location
- McAllen, TX
- Eligibility basics
- Ages 55+
Questions
If I fit this group, will I qualify?
Not necessarily. Age and sex limits are only the first filter. Each study has its own inclusion and exclusion criteria, and the research team decides at screening.
Where do these age and sex limits come from?
From the eligibility section of each study’s official ClinicalTrials.gov record. We don’t infer eligibility from anything else.