Who can join
Studies for adults 50 and older
These studies set a minimum age of 50 or older in their official record. Many look at conditions more common with age, and some vaccine and memory studies specifically need older participants.
417 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- RecruitingPhase 3
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- Location
- Orange, CA + 7 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 2/Phase 3
Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer's Disease Dementia
Exciva GmbH
- Location
- Murrieta, CA + 6 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 1/Phase 2
A Study to Evaluate KRIYA-825 (VV-14295) in Adults With Geographic Atrophy Secondary to Age-related Macular Degeneration
Kriya Therapeutics, Inc.
- Location
- Erie, PA
- Eligibility basics
- Ages 55–80
- RecruitingPhase 2/Phase 3
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)
EyeBiotech Ltd.
- Location
- Gilbert, AZ + 51 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 1
Intravitreal (IVT) Pozelimab for Geographic Atrophy (GA) in Adult Participants
Regeneron Pharmaceuticals
- Location
- Lakewood, CO + 4 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 2
Ixoberogene Soroparvovec (Ixo-vec) Contralateral Dosing Study in Participants With Neovascular Age-related Macular Degeneration
Adverum Biotechnologies, Inc.
- Location
- Phoenix, AZ + 11 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)
Anthos Therapeutics, Inc.
- Location
- Birmingham, AL + 131 other US sites
- Eligibility basics
- Ages 65+
- RecruitingPhase 1/Phase 2
Study to Assess the Adverse Events and How Intravitreal ABBV-6628 Moves Through the Body of Adult Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration
AbbVie
- Location
- Carmel, IN + 4 other US sites
- Eligibility basics
- Ages 50+
- Recruiting
Safety and Effectiveness of the Optilume® BPH Catheter System in a Post-Market Study
Urotronic Inc.
- Location
- Little Rock, AR + 6 other US sites
- Eligibility basics
- Ages 50+ · Men only
- RecruitingPhase 1/Phase 2
Safety, Tolerability and Exploratory Efficacy of EC5026 in Parkinson's Disease (STEP Study)
EicOsis Human Health Inc.
- Location
- Sacramento, CA
- Eligibility basics
- Ages 50–80
- RecruitingPhase 3
A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).
Eli Lilly and Company
- Location
- Huntington Beach, CA + 41 other US sites
- Eligibility basics
- Ages 55+
- RecruitingPhase 2/Phase 3
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study
Kardigan, Inc.
- Location
- Birmingham, AL + 46 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
Study to Evaluate Long-Term Safety of Intravitreal OTX-TKI (Axitinib Implant) in Participants With Neovascular Age-Related Macular Degeneration Who Successfully Completed 2-Year OTX-TKI-2023-AMD-301 or…
Ocular Therapeutix, Inc.
- Location
- Bakersfield, CA + 7 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)
Bristol-Myers Squibb
- Location
- Gilbert, AZ + 2 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 1
A Study on the Safety and Immune Response of Investigational mRNA Seasonal Flu/COVID-19 Combination Vaccine in Adults
GlaxoSmithKline
- Location
- Anniston, AL + 11 other US sites
- Eligibility basics
- Ages 65–85
- Recruiting
Wearable Sensory Prosthesis to Improve Coordination, Walking, and Physical Activity
RxFunction Inc.
- Location
- Jacksonville, FL
- Eligibility basics
- Ages 60+
- RecruitingPhase 2
A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in…
Apellis Pharmaceuticals, Inc.
- Location
- Gilbert, AZ + 77 other US sites
- Eligibility basics
- Ages 60+
- RecruitingPhase 2
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis
Novartis Pharmaceuticals
- Location
- Huntsville, AL + 29 other US sites
- Eligibility basics
- Ages 50–80
- Recruiting
Preventing Medication Mismanagement in People Living With Dementia
HiDO Technologies
- Location
- Folsom, CA
- Eligibility basics
- Ages 65+
- Recruiting
Steady Stride Fall Prevention Protocol vs Standard of Care
Steady Strides: Fall Prevention and Stroke Rehabilitation Medical Institute
- Location
- Baltimore, MD
- Eligibility basics
- Ages 65+
- RecruitingPhase 2
Open-label Extension Study in Participants With Early Alzheimer's Disease
GlaxoSmithKline
- Location
- Maitland, FL + 8 other US sites
- Eligibility basics
- Ages 50–85
- RecruitingPhase 1/Phase 2
A Phase 1/2 Study to Evaluate the Safety and Efficacy of Intravitreal Administration of BS01 in Patients With Geographic Atrophy Secondary to Dry AMD
Bionic Sight LLC
- Location
- Edison, NJ
- Eligibility basics
- Ages 50–85
- Recruiting
ExAblate Blood-Brain Barrier (BBB) Disruption for the Treatment of Alzheimer's Disease
InSightec
- Location
- Delray Beach, FL + 5 other US sites
- Eligibility basics
- Ages 50–85
- Recruiting
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR
Edwards Lifesciences
- Location
- Huntsville, AL + 49 other US sites
- Eligibility basics
- Ages 65+
Questions
If I fit this group, will I qualify?
Not necessarily. Age and sex limits are only the first filter. Each study has its own inclusion and exclusion criteria, and the research team decides at screening.
Where do these age and sex limits come from?
From the eligibility section of each study’s official ClinicalTrials.gov record. We don’t infer eligibility from anything else.