Who can join
Studies for adults 50 and older
These studies set a minimum age of 50 or older in their official record. Many look at conditions more common with age, and some vaccine and memory studies specifically need older participants.
417 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
Studies
- Recruiting
Trial of the F2 Filter and Delivery System for Embolic Protection During TAVR
EnCompass Technologies, Inc.
- Location
- Indianappolis, IN + 4 other US sites
- Eligibility basics
- Ages 50+
- Recruiting
2910 nm Erbium-Doped Fluoride Fiber Glass Laser for the Treatment of Advanced Perioral Lines and Wrinkles
FA Corporation
- Location
- Houston, TX
- Eligibility basics
- Ages 50–80
- RecruitingPhase 1/Phase 2
Safety and Tolerability of RPE Stem Cell-derived RPE(RPESC-RPE) Transplantation in Patients With Dry Age-related Macular Degeneration (AMD)
Luxa Biotechnology, LLC
- Location
- Beverly Hills, CA + 2 other US sites
- Eligibility basics
- Ages 55+
- Recruiting
Cataract Surgery in Conjunction With Ab-interno Canaloplasty Compared to Cataract Surgery Only in Patients With Mild to Moderate Primary Open-Angle Glaucoma
Nova Eye, Inc.
- Location
- Sugar Land, TX
- Eligibility basics
- Ages 55+
- RecruitingPhase 1
Study to Evaluate the Safety of CG-P5 Peptide Eye Drops in Patients Diagnosed With Age-related Wet Macular Degeneration
Caregen Co. Ltd.
- Location
- Manchester, CT + 6 other US sites
- Eligibility basics
- Ages 50+
- Recruiting
Multicenter Clinical Study of the SING-IMT in Patients with Late-stage AMD
VisionCare, Inc.
- Location
- Loma Linda, CA + 9 other US sites
- Eligibility basics
- Ages 65+
- RecruitingPhase 1
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Preserved Ejection Fraction
Sardocor Corp.
- Location
- Durham, NC
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteers
Amyloid PET Imaging in the Baltimore Longitudinal Study of Aging
National Institute on Aging (NIA)
- Location
- Baltimore, MD
- Eligibility basics
- Ages 55–110
- RecruitingHealthy volunteers
Oral Health Intervention in Adult Primary Care
Case Western Reserve University
- Location
- Cleveland, OH
- Eligibility basics
- Ages 55+
- RecruitingHealthy volunteers
Effect of Vestibular Perceptual Learning on Vestibular Thresholds and Balance
Ohio State University
- Location
- Columbus, OH
- Eligibility basics
- Ages 65–89
- RecruitingHealthy volunteers
Multifocal HD-tDCS and Motor Function
University of Michigan
- Location
- Ann Arbor, MI
- Eligibility basics
- Ages 65–85
- RecruitingHealthy volunteers
Accelerated Resolution Therapy for Early Maladaptive Grief
Mayo Clinic
- Location
- Phoenix, AZ + 3 other US sites
- Eligibility basics
- Ages 55+
- RecruitingHealthy volunteers
An Educational Intervention (Lung Toolkit) for Improving Knowledge About Lung Cancer and Screening Among American Indian and Alaskan Native Cigarette Smokers, Lung PATHS Trial
Fred Hutchinson Cancer Center
- Location
- Seattle, WA
- Eligibility basics
- Ages 50–80
- RecruitingHealthy volunteers
Community Park-Based Programs for Health Promotion: Active Older Adults Prospective Cohort Study
Duke University
- Location
- Miami, FL
- Eligibility basics
- Ages 50–95
- RecruitingHealthy volunteers
Urine Prostate Screening Integrated With MRI for Early Detection of Prostate Cancer, UPRISE Trial
University of Michigan Rogel Cancer Center
- Location
- Ann Arbor, MI
- Eligibility basics
- Ages 50–75 · Men only
- RecruitingHealthy volunteersPhase 2
Ongoing Lung Decline With Age Intensified Response
Cedars-Sinai Medical Center
- Location
- Los Angeles, CA
- Eligibility basics
- Ages 60+
- RecruitingHealthy volunteers
Glaucoma Screening to Enhance At-Risk Californians' Health
University of California, San Francisco
- Location
- Fremont, CA + 1 other US site
- Eligibility basics
- Ages 50+
- RecruitingHealthy volunteers
Use of CA125 and Complementary Biomarkers for the Early Detection of Ovarian Cancer in Low Risk Women
M.D. Anderson Cancer Center
- Location
- Miami, FL + 9 other US sites
- Eligibility basics
- Ages 50–74 · Women only
- RecruitingHealthy volunteers
A Study of Lung Cancer Screening in People With Unexplained Weight Loss
Memorial Sloan Kettering Cancer Center
- Location
- Basking Ridge, NJ + 7 other US sites
- Eligibility basics
- Ages 50–80
- RecruitingHealthy volunteers
MCI Speech in Noise
Dartmouth-Hitchcock Medical Center
- Location
- Lebanon, NH
- Eligibility basics
- Ages 55–80
- RecruitingHealthy volunteers
Nicotinamide Mononucleotide Supplementation for Exercise Tolerance Improvement in Healthy Older Adults
Scott Silveira
- Location
- Beverly Hills, CA
- Eligibility basics
- Ages 60–80
- RecruitingHealthy volunteers
Following the Sound of Music
Northeastern University
- Location
- Boston, MA
- Eligibility basics
- Ages 60–101
- RecruitingHealthy volunteers
Social Connection Collective for Older Adults in Subsidized Housing
Johns Hopkins University
- Location
- Baltimore, MD
- Eligibility basics
- Ages 62+
- RecruitingHealthy volunteers
Wake Forest Alzheimer's Disease Clinical Core
Wake Forest University Health Sciences
- Location
- Winston-Salem, NC
- Eligibility basics
- Ages 55+
Questions
If I fit this group, will I qualify?
Not necessarily. Age and sex limits are only the first filter. Each study has its own inclusion and exclusion criteria, and the research team decides at screening.
Where do these age and sex limits come from?
From the eligibility section of each study’s official ClinicalTrials.gov record. We don’t infer eligibility from anything else.