Location · California
Clinical trials recruiting in California
1898 recruiting studies have at least one site in California; 701 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,898 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 2
A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia
Vima Therapeutics
- Location
- Irvine, CA + 36 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
Reducing Adverse Vascular Outcomes With Factor XI Inhibition in Adult Participants With Peripheral Artery Disease
Regeneron Pharmaceuticals
- Location
- Los Angeles, CA + 26 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease
Pfizer
- Location
- La Palma, CA + 58 other US sites
- Eligibility basics
- Ages 35–80
- RecruitingPhase 2
A Study to Assess the Tolerability of Ianalumab (VAY736) With Investigator's Choice Thrombopoietin Receptor Agonist (IC TPO-RA) in Patients With Primary Immune Thrombocytopenia (ITP)
Novartis Pharmaceuticals
- Location
- Torrance, CA + 18 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
Study to Evaluate the Efficacy and Safety of BMN 333 Versus Vosoritide in Children With Achondroplasia
BioMarin Pharmaceutical
- Location
- Oakland, CA + 7 other US sites
- Eligibility basics
- Ages 2–17
- RecruitingPhase 2
A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's Disease
Eli Lilly and Company
- Location
- Los Angeles, CA + 11 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
An Exploratory Efficacy and Safety Study of DFL24498 Topical Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease
Dompé Farmaceutici S.p.A
- Location
- Azusa, CA + 12 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Trial Comparing the Safety and Efficacy of Two Different Oral VPV Doses With Placebo as Treatment for RV in Participants With COPD
Altesa Biosciences, Inc.
- Location
- Newport Beach, CA + 28 other US sites
- Eligibility basics
- Ages 40–85
- RecruitingPhase 3
A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus
AstraZeneca
- Location
- Encinitas, CA + 12 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants With Upper Limb Essential Tremor
AbbVie
- Location
- Carlsbad, CA + 17 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 2
A Study to Learn About The Effects of Felzartamab on Thyroid Function and Its Safety in Adults With Graves' Disease Ages 18 to 75 Years Old
Biogen
- Location
- Los Angeles, CA + 10 other US sites
- Eligibility basics
- Ages 18–75
- Recruiting
Evaluation of Orthokeratology Lenses With a 5MM Optic Zone Diameter
CooperVision International Limited (CVIL)
- Location
- Pleasanton, CA + 1 other US site
- Eligibility basics
- Ages 7–35
- RecruitingPhase 3
A Study to Learn About the Study Medicine Called Tilrekimig in People With Moderate-to Severe Eczema
Pfizer
- Location
- Huntington Beach, CA + 11 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 2/Phase 3
Phase 2/3 Efficacy and Safety of PP405 in Adult Males
Pelage Pharmaceuticals, Inc.
- Location
- Manhattan Beach, CA + 26 other US sites
- Eligibility basics
- Ages 18–55 · Men only
- Recruiting
A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With…
LivaNova
- Location
- Costa Mesa, CA + 49 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
EFS of the DUO System for Tricuspid Regurgitation
CroiValve Limited
- Location
- Thousand Oaks, CA + 12 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Thrombectomy Using Pulsed Aspiration for Reperfusion of Brain Occlusions
RapidPulse, Inc
- Location
- Torrance, CA + 12 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 1/Phase 2
A Study to Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265) in Pediatric, Adolescent and Adult Participants With Hemophilia B
Regeneron Pharmaceuticals
- Location
- Los Angeles, CA + 16 other US sites
- Eligibility basics
- Ages 2+ · Men only
- Recruiting
Prevail Global Study
Medtronic Vascular
- Location
- Stanford, CA + 53 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
AstraZeneca
- Location
- Huntington Beach, CA + 151 other US sites
- Eligibility basics
- Ages 40+
- Recruiting
Evaluation of a Switchable Acrylic Adhesive Drape for Safer Removal in Negative Pressure Wound Therapy Applications.
Global Biomedical Technologies, LLC
- Location
- Los Angeles, CA + 2 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Single-Dose Study to Evaluate Safety and Efficacy of CS-1103 in Participants Receiving a Single Dose of Methamphetamine
Clear Scientific, Inc.
- Location
- Glendale, CA
- Eligibility basics
- Ages 18–55
- RecruitingPhase 1/Phase 2
A Multicenter Study to Evaluate Safety, Tolerability, and Clinical Responses of DSP-1083 Into Subjects With Parkinson's Disease
Sumitomo Pharma America, Inc.
- Location
- La Jolla, CA + 2 other US sites
- Eligibility basics
- Ages 40–72
- Recruiting
Safety and Efficacy of Endovascular Treatment of Intracranial Aneurysms With Surpass Elite With GUARDian Flow Diverter (GUARD)
Stryker Neurovascular
- Location
- Davis, CA + 19 other US sites
- Eligibility basics
- Ages 18–80