Location · California
Clinical trials recruiting in California
1898 recruiting studies have at least one site in California; 701 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,898 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 2
An Open-Label Extension Study of ORKA-001 in Participants With Plaque Psoriasis
Oruka Therapeutics, Inc.
- Location
- Fountain Valley, CA + 22 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002)
Merck Sharp & Dohme LLC
- Location
- Anaheim, CA + 10 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)
Amgen
- Location
- Chula Vista, CA + 51 other US sites
- Eligibility basics
- Ages 18–99
- RecruitingPhase 3
A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)
Definium Therapeutics US, Inc.
- Location
- Orange, CA + 22 other US sites
- Eligibility basics
- Ages 18–74
- RecruitingPhase 2
A Clinical Trial of MK-7262 and Enlicitide in Participants With High Lipoprotein(a) (MK-7262-004)
Merck Sharp & Dohme LLC
- Location
- Beverly Hills, CA + 23 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study of WIN378 in Participants With Moderate to Severe COPD (Sirius)
Windward Bio
- Location
- Los Angeles, CA + 8 other US sites
- Eligibility basics
- Ages 40–80
- RecruitingPhase 2
A Study to Investigate the Safety and Effectiveness of SAR448851 in Participants With Early Alzheimer's Disease
Sanofi
- Location
- Long Beach, CA + 9 other US sites
- Eligibility basics
- Ages 55–85
- RecruitingPhase 2
A Study of MZE782 in Adults With PKU
Maze Therapeutics
- Location
- Oakland, CA + 6 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-004)
Merck Sharp & Dohme LLC
- Location
- Glendale, CA + 27 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate the Safety and Effectiveness of Upadacitinib in Pediatric Participants With Alopecia Areata
AbbVie
- Location
- Los Angeles, CA + 8 other US sites
- Eligibility basics
- Ages 6–17
- RecruitingPhase 3
An Open-Label, Safety and Efficacy Study of Cebranopadol in Participants With Acute Pain With Surgical or Non-Surgical Origin
Adneuris Therapeutics, Inc.
- Location
- Riverside, CA + 14 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Phase 3 Study of Denifanstat in Participants With Moderate to Severe Acne (AURORA)
Sagimet Biosciences Inc.
- Location
- Fremont, CA + 17 other US sites
- Eligibility basics
- Ages 12+
- Recruiting
Neutrophil and Monocyte Deactivation Via the SeLective CytopheretIc Device - A Randomized Clinical Trial in Acute Kidney Injury
SeaStar Medical
- Location
- Los Angeles, CA + 23 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell…
Incyte Corporation
- Location
- Palo Alto, CA + 29 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Phase 2 Efficacy and Safety Study of GAL-101, 2% Ophthalmic Solution in Non-foveal Geographic Atrophy Secondary to Non-neovascular AMD
Galimedix Therapeutics Inc
- Location
- Beverly Hills, CA + 1 other US site
- Eligibility basics
- Ages 55+
- RecruitingPhase 2/Phase 3
A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease
Biohaven Therapeutics Ltd.
- Location
- Irvine, CA + 24 other US sites
- Eligibility basics
- Ages 40–80
- RecruitingPhase 2
A Long-term Safety and Efficacy Study Evaluating APG777 in Atopic Dermatitis
Apogee Therapeutics, Inc.
- Location
- Fountain Valley, CA + 22 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study Investigating Intravenous Human Normal Immunoglobulin 10% in Adults With Chronic Immune Thrombocytopenia (ITP)
Kedrion S.p.A.
- Location
- Los Angeles, CA + 2 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis
AbbVie
- Location
- San Diego, CA + 11 other US sites
- Eligibility basics
- Ages 2–17
- Recruiting
Diagnosing Epilepsy To EffeCT Change
Epiminder America, Inc.
- Location
- Irvine, CA + 21 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study to Evaluate the Maintenance Effect of Osavampator as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Neurocrine Biosciences
- Location
- Oceanside, CA + 19 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
REGN7508 Versus Acetylsalicylic Acid (ASA) for Venous Thromboprophylaxis After Total Knee Arthroplasty in Adult Participants
Regeneron Pharmaceuticals
- Location
- La Mesa, CA + 35 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma
Eli Lilly and Company
- Location
- Newport Beach, CA + 15 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-1)
Generate Biomedicines
- Location
- Northridge, CA + 35 other US sites
- Eligibility basics
- Ages 12–80