Location · California
Clinical trials recruiting in California
1898 recruiting studies have at least one site in California; 701 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,898 recruiting studiesSource: ClinicalTrials.gov, refreshed October 26, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 2
A Study to Assess the Safety, Tolerability and Efficacy of ION775
Ionis Pharmaceuticals, Inc.
- Location
- Lincoln, CA + 15 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events
Novo Nordisk A/S
- Location
- Walnut Creek, CA + 9 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 4
A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)
Alpha Cognition, Inc
- Location
- Irvine, CA + 21 other US sites
- Eligibility basics
- Ages 50+
- RecruitingPhase 3
Study to Determine if BHV-1300 is Effective and Safe in Adults With Graves' Disease
Biohaven Therapeutics Ltd.
- Location
- Burbank, CA + 52 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- Location
- Anaheim, CA + 56 other US sites
- Eligibility basics
- Ages 55–90
- Recruiting
Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
Abbott Medical Devices
- Location
- Los Angeles, CA + 24 other US sites
- Eligibility basics
- Ages 22–70
- RecruitingPhase 3
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
Cybin IRL Limited
- Location
- Glendale, CA + 27 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 3
A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
Hoffmann-La Roche
- Location
- Garden Grove, CA + 91 other US sites
- Eligibility basics
- Ages 16–80
- RecruitingPhase 1/Phase 2
DFT383 in Pediatric Participants With Nephropathic Cystinosis
Novartis Pharmaceuticals
- Location
- San Diego, CA + 5 other US sites
- Eligibility basics
- Ages 2–5
- RecruitingPhase 3
A Study to Assess Efficacy and Safety of Empasiprubart Versus IVIg in Adults With CIDP
argenx
- Location
- Rancho Mirage, CA + 15 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Test Whether BI 1815368 Helps People With an Eye Condition Called Diabetic Macular Edema
Boehringer Ingelheim
- Location
- Arcadia, CA + 21 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Phase 2 Study of LTI-03 in Patients With Idiopathic Pulmonary Fibrosis
Rein Therapeutics
- Location
- Los Angeles, CA + 19 other US sites
- Eligibility basics
- Ages 40+
- RecruitingPhase 3
A Study to Assess the Efficacy and Safety of Empasiprubart in Adults With CIDP
argenx
- Location
- Rancho Mirage, CA + 12 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
BIOTRONIK Investigation of the LivIQ Leadless Pacemaker System
Biotronik, Inc.
- Location
- Burlingame, CA + 23 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Obe-cel in Refractory Progressive Forms of Multiple Sclerosis
Autolus Limited
- Location
- Palo Alto, CA
- Eligibility basics
- Ages 18–60
- RecruitingPhase 3
A Study to Evaluate Atumelnant in Adults With Congenital Adrenal Hyperplasia
Crinetics Pharmaceuticals Inc.
- Location
- Los Angeles, CA + 12 other US sites
- Eligibility basics
- Ages 18–74
- RecruitingPhase 2/Phase 3
A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH)
Crinetics Pharmaceuticals Inc.
- Location
- San Francisco, CA + 9 other US sites
- Eligibility basics
- Ages 1–17
- RecruitingPhase 3
A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
Sanofi
- Location
- Coronado, CA + 36 other US sites
- Eligibility basics
- Ages 16–80
- RecruitingPhase 3
Evaluation of IV AMBTX-01 (Neridronate) for Treatment of CRPS Type 1 (CRPS-RISE)
Ambros Therapeutics, Inc.
- Location
- La Jolla, CA + 29 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safey of PTP-001 (MOTYS™) in Knee Osteoarthritis Patients (MOTION-P)
Doron Therapeutics Inc.
- Location
- La Mesa, CA + 7 other US sites
- Eligibility basics
- Ages 40–80
- RecruitingPhase 3
Efficacy and Safety of FID 123472 Ophthalmic Solution for Ocular Redness in Adults
Alcon Research
- Location
- Los Angeles, CA + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC PFS in Adult Participants With Graves' Disease
argenx
- Location
- Orange, CA + 26 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
NORM-HF Pivotal Study
Foundry Innovation & Research 1, Limited (FIRE1)
- Location
- Chula Vista, CA + 22 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2/Phase 3
Surabgene Lomparvovec Administered in the Suprachoroidal Space in Adult Participants With Diabetic Retinopathy Without Center-Involved Diabetic Macular Edema
AbbVie
- Location
- Bakersfield, CA + 36 other US sites
- Eligibility basics
- Ages 18+