Location · California
Clinical trials recruiting in California
1900 recruiting studies have at least one site in California; 700 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,900 recruiting studiesSource: ClinicalTrials.gov, refreshed October 27, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 2
A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease
Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)
- Location
- Lancaster, CA + 22 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 1/Phase 2
ATTUNE: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intrathecally-Administered ION440 in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome (MDS)
Ionis Pharmaceuticals, Inc.
- Location
- San Diego, CA + 7 other US sites
- Eligibility basics
- Ages 2–65 · Men only
- RecruitingPhase 2
Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis
CSL Behring
- Location
- Oakland, CA + 18 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 2
A Study of TAK-360 in Adults With Narcolepsy Without Cataplexy (NT2)
Takeda
- Location
- Chula Vista, CA + 24 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 2
A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis
AbbVie
- Location
- Beverly Hills, CA + 48 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
Bristol-Myers Squibb
- Location
- Fullerton, CA + 22 other US sites
- Eligibility basics
- Ages 60–85
- RecruitingPhase 3
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease
Bristol-Myers Squibb
- Location
- Garden Grove, CA + 21 other US sites
- Eligibility basics
- Ages 55–90
- RecruitingPhase 3
REGN7508 Versus Apixaban and Enoxaparin for Thromboprophylaxis After Total Knee Arthroplasty in Adults
Regeneron Pharmaceuticals
- Location
- Riverside, CA + 17 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
Amgen
- Location
- Covina, CA + 136 other US sites
- Eligibility basics
- Ages 45–99
- RecruitingPhase 3
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)
Eli Lilly and Company
- Location
- Canoga Park, CA + 136 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH) (ROCSTAR STUDY)
AllRock Bio, Inc.
- Location
- Rancho Cordova, CA + 10 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:
Eli Lilly and Company
- Location
- Anaheim, CA + 36 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight
Eli Lilly and Company
- Location
- Los Angeles, CA + 17 other US sites
- Eligibility basics
- Ages 18+ · Women only
- RecruitingPhase 3
Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease
Eli Lilly and Company
- Location
- Northridge, CA + 27 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
Study to Assess the Effects of ALN-ANG3 in Adult Participants With Diabetic Kidney Disease
Regeneron Pharmaceuticals
- Location
- Huntington Beach, CA + 55 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 3
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
Eli Lilly and Company
- Location
- Canoga Park, CA + 59 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy
argenx
- Location
- Stanford, CA + 10 other US sites
- Eligibility basics
- Ages 5–17
- RecruitingPhase 2
A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression
Draig Therapeutics Ltd
- Location
- Oceanside, CA + 18 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
Eli Lilly and Company
- Location
- Fountain Valley, CA + 37 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight
Eli Lilly and Company
- Location
- Long Beach, CA + 22 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
Eli Lilly and Company
- Location
- Anaheim, CA + 38 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
A Study of LY4395089 and Mirikizumab (LY3074828) Given Together and Mirikizumab (Alone) in Adults With Crohn's Disease
Eli Lilly and Company
- Location
- Oxnard, CA + 9 other US sites
- Eligibility basics
- Ages 18–80
- Recruiting
Non-invasive Vagus Nerve Stimulation (nVNS) for Post-Traumatic Stress Disorder (PTSD)
Acacia Clinics
- Location
- Sunnyvale, CA
- Eligibility basics
- Ages 18–70
- RecruitingPhase 2
A Study of LY4005130 in Adult Participants With Non-Segmental Vitiligo
Eli Lilly and Company
- Location
- Fremont, CA + 17 other US sites
- Eligibility basics
- Ages 18–75