Location · California
Clinical trials recruiting in California
1900 recruiting studies have at least one site in California; 700 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,900 recruiting studiesSource: ClinicalTrials.gov, refreshed October 27, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 2
An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.
Novartis Pharmaceuticals
- Location
- Garden Grove, CA + 18 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Study to Evaluate the Pharmacodynamics of a Combination of QCZ484 and Inclisiran in Participants With Hypertension and Concomitant Hypercholesterolemia
Novartis Pharmaceuticals
- Location
- Lincoln, CA + 26 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2/Phase 3
KYSA-6: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, in Patients With Generalized Myasthenia Gravis
Kyverna Therapeutics
- Location
- Los Angeles, CA + 9 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1
Healx Limited
- Location
- Los Angeles, CA + 13 other US sites
- Eligibility basics
- Ages 12+
- RecruitingPhase 2
Study to Evaluate the Impact of Iptacopan on Top of SOC on Biopsy Changes in Kidneys of Adult Patients With IgAN
Novartis Pharmaceuticals
- Location
- Los Angeles, CA + 8 other US sites
- Eligibility basics
- Ages 18–99
- RecruitingPhase 2
Study to Assess the Safety, Tolerability, and Treatment Response of GXV813 in Hospitalized Adults With Schizophrenia
Novartis Pharmaceuticals
- Location
- Pico Rivera, CA + 6 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 4
Study to Assess Safety, Pharmacokinetics, and Treatment Effect of Cabtreo
Bausch Health Americas, Inc.
- Location
- Freemont, CA + 13 other US sites
- Eligibility basics
- Ages 9–11
- RecruitingPhase 1/Phase 2
A Study to Assess the Safety and Efficacy of IPN10200 in Adult Participants With Upper Limb Spasticity.
Ipsen
- Location
- Downey, CA + 3 other US sites
- Eligibility basics
- Ages 18–70
- RecruitingPhase 3
Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol
Axsome Therapeutics, Inc.
- Location
- Encino, CA + 35 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingPhase 3
eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation
GlaxoSmithKline
- Location
- Newport Beach, CA + 37 other US sites
- Eligibility basics
- Ages 40–75
- RecruitingPhase 2
Phase 2b Study of RPT904 as Monotherapy in Participants With IgE-Mediated Food Allergy
RAPT Therapeutics, Inc., a member of the GSK plc group of companies
- Location
- Palo Alto, CA + 21 other US sites
- Eligibility basics
- Ages 12–55
- Recruiting
Antibiotic Device for Osteomyelitis of the Extremities Pivotal Trial - Genex With Gentamicin.
Biocomposites Ltd
- Location
- San Diego, CA + 3 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Early Feasibility Study (EFS) of the Nyra Cardiac Leaflet Enhancer (CARLEN) System
Nyra Medical, Inc.
- Location
- Sacramento, CA + 2 other US sites
- Eligibility basics
- Ages 21+
- RecruitingPhase 2
A Clinical Study to Evaluate the Efficacy and Safety of Frevecitinib (KN-002) in Patients With Severe Asthma
Kinaset Therapeutics Inc
- Location
- Lancaster, CA + 8 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Study to Evaluate Efficacy and Safety of Roluperidone in Adult Subjects With Negative Symptoms and Stable Positive Symptoms of Schizophrenia and to Evaluate the Relapse Rate of Roluperidone and Antipsychotic Medications
Minerva Neurosciences
- Location
- Bellflower, CA + 12 other US sites
- Eligibility basics
- Ages 18–55
- RecruitingPhase 3
A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.
AbbVie
- Location
- Anaheim, CA + 30 other US sites
- Eligibility basics
- Ages 10–17
- RecruitingPhase 3
A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis
Janssen Research & Development, LLC
- Location
- Pasadena, CA + 10 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder
Syndeio Biosciences, Inc
- Location
- Montclair, CA + 22 other US sites
- Eligibility basics
- Ages 18–64
- Recruiting
Early Feasibility Study (EFS) Evaluating Percutaneous Repair of the Atrial Septum With a Novel PFO Occluder: The PROTEA-PFO Study
Recross Cardio, Inc.
- Location
- Los Angeles, CA + 4 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
A Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASH
GlaxoSmithKline
- Location
- Arcadia, CA + 62 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Study to Evaluate LB-102 for the Treatment of Adult Patients With Acute Schizophrenia
LB Pharmaceuticals Inc.
- Location
- Culver City, CA + 12 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 2
Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE.
LB Pharmaceuticals Inc.
- Location
- Bellflower, CA + 25 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work Disorder (SUSTAIN)
Axsome Therapeutics, Inc.
- Location
- Anaheim, CA + 37 other US sites
- Eligibility basics
- Ages 18–65
- RecruitingPhase 3
Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals
- Location
- San Francisco, CA + 3 other US sites
- Eligibility basics
- Ages 2–11