Location · California
Clinical trials recruiting in California
1900 recruiting studies have at least one site in California; 700 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,900 recruiting studiesSource: ClinicalTrials.gov, refreshed October 27, 2026How we list studies
More recruiting studies (pay not posted)
- Recruiting
Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions
Teleflex
- Location
- Concord, CA + 9 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
A Pivotal Study to Evaluate the Effectiveness of Isometric Handgrip Therapy in Elevated Blood Pressure and Hypertensive Subjects
Zona Health, Inc
- Location
- Valley Village, CA + 9 other US sites
- Eligibility basics
- Ages 22+
- RecruitingPhase 3
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Neurocrine Biosciences
- Location
- Glendale, CA + 38 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
A Phase 1/2 Study of the Safety and Efficacy of MVX-220 in Angelman Syndrome
MavriX Bio, LLC
- Location
- Los Angeles, CA + 2 other US sites
- Eligibility basics
- Ages 4–50
- Recruiting
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction
Edwards Lifesciences
- Location
- San Francisco, CA + 20 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 2
PHENOGENE-1A (Cromolyn) Treatment in Patients With Mild to Moderate ALS
PhenoNet, Inc.
- Location
- La Jolla, CA + 4 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study)
ViiV Healthcare
- Location
- Bakersfield, CA + 32 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)
Chugai Pharmaceutical
- Location
- Orange, CA + 6 other US sites
- Eligibility basics
- Ages 18–85
- Recruiting
Ceribell Delirium Monitor Outcomes Pilot Study
Ceribell Inc.
- Location
- Irvine, CA
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Examination of How the Duration of Fasting and Temporary Stopping of GLP-1 Medications Affect the Amount of Food Left in the Stomach in People Using Liraglutide (Injected), Semaglutide (Taken by Mouth) or Semaglutide…
Novo Nordisk A/S
- Location
- Cypress, CA
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Assessing the Safety, Tolerability, and Efficacy of APR-2020 in Pediatric and Adolescent Subjects With RPS19 Deficient Diamond-Blackfan Anemia
Apriligen, Inc.
- Location
- Stanford, CA + 1 other US site
- Eligibility basics
- Ages 2–25
- Recruiting
Effectiveness of Audio Cues to Achieve Positional Therapy in Patients With Positional Obstructive Sleep Apnea
SleepDev, Inc
- Location
- Burlingame, CA
- Eligibility basics
- Ages 18–75
- RecruitingPhase 3
Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy
Vertex Pharmaceuticals Incorporated
- Location
- Canoga Park, CA + 69 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 1
Phase 1a/b Tolerability of NTR-1011 in Healthy Adults and Adult Patients With SLE and RA
Neutrolis
- Location
- Apple Valley, CA + 6 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 1
ISP-001: Sleeping Beauty Transposon-Engineered B Cells for MPS I
Immusoft of CA, Inc.
- Location
- Oakland, CA + 1 other US site
- Eligibility basics
- Ages 10+
- Recruiting
Treating Pulmonary Embolism With Laguna Thrombectomy System (TRUST)
Innova Vascular, Inc.
- Location
- Irvine, CA + 12 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 3
Beeline: A Phase 3 Study in GRIN-related Neurodevelopmental Disorder
GRIN Therapeutics, Inc.
- Location
- Los Angeles, CA + 15 other US sites
- Eligibility basics
- Ages 1 mo–18
- Recruiting
Coherent Sine Burst Electroporation (CSE) Ablation System US IDE Study for Patients With Atrial Fibrillation
Arga Medtech SA
- Location
- San Diego, CA + 17 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 2
A Study of TAK-360 in Adults With Idiopathic Hypersomnia
Takeda
- Location
- Redwood City, CA + 12 other US sites
- Eligibility basics
- Ages 18–70
- Recruiting
MISHA Post-Market Clinical Study
Moximed
- Location
- Sonoma, CA + 3 other US sites
- Eligibility basics
- Ages 25–65
- Recruiting
Post Market Study for VasQ, an External Support Implant for Arteriovenous Fistula
Laminate Medical Technologies
- Location
- Long Beach, CA + 7 other US sites
- Eligibility basics
- Ages 18–80
- Recruiting
MOTION Clinical Trial
Moximed
- Location
- Oceanside, CA + 5 other US sites
- Eligibility basics
- Any age listed
- RecruitingPhase 3
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)
Anthos Therapeutics, Inc.
- Location
- Huntington Beach, CA + 131 other US sites
- Eligibility basics
- Ages 65+
- RecruitingPhase 3
Study of Efficacy and Safety of Iptacopan in Participants With IC-MPGN
Novartis Pharmaceuticals
- Location
- Los Angeles, CA + 21 other US sites
- Eligibility basics
- Ages 12–60