Location · California
Clinical trials recruiting in California
1900 recruiting studies have at least one site in California; 700 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,900 recruiting studiesSource: ClinicalTrials.gov, refreshed October 27, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 1/Phase 2
Safety and Tolerability of RPE Stem Cell-derived RPE(RPESC-RPE) Transplantation in Patients With Dry Age-related Macular Degeneration (AMD)
Luxa Biotechnology, LLC
- Location
- Beverly Hills, CA + 2 other US sites
- Eligibility basics
- Ages 55+
- Recruiting
Nafamostat Efficacy in Phase 3 Registrational CRRT Study
Talphera, Inc
- Location
- Los Angeles, CA + 8 other US sites
- Eligibility basics
- Ages 18–80
- RecruitingPhase 4
Effect of Amnio-Maxx on the Healing Rate of Chronic Diabetic Foot Ulcers.
Royal Biologics
- Location
- Burbank, CA + 7 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Safety and Device Performance of the Uriprene® Degradable Temporary Ureteral Stent Following Uncomplicated Ureteroscopy
Adva-Tec
- Location
- Los Angeles, CA + 3 other US sites
- Eligibility basics
- Ages 21–80
- Recruiting
Plexaa For Preconditioning: Gender Affirming Mastectomy
Plexaa Ltd
- Location
- Palo Alto, CA
- Eligibility basics
- Ages 18+ · Women only
- Recruiting
Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System
Aria CV, Inc
- Location
- Los Angeles, CA + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib
Kartos Therapeutics, Inc.
- Location
- La Jolla, CA + 57 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 2
An Eight-Week Study to Evaluate the Safety and Efficacy of VSJ-110 Compared to Placebo in the Treatment of Dry Eye
Vanda Pharmaceuticals
- Location
- Newport Beach, CA + 1 other US site
- Eligibility basics
- Ages 18+
- RecruitingPhase 4
Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Extended-release Tablets in Pediatric Subjects Aged 5 to 17 Years With Active, Mild to Moderate Ulcerative Colitis
Bausch Health Americas, Inc.
- Location
- Garden Grove, CA + 3 other US sites
- Eligibility basics
- Ages 5–17
- RecruitingPhase 3
Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients
AB Science
- Location
- Los Angeles, CA + 5 other US sites
- Eligibility basics
- Ages 18–81
- RecruitingPhase 1
Single and Multiple Dose Escalation of PHIN-214 in Child-Pugh A and B Liver Cirrhotics
PharmaIN
- Location
- Coronado, CA + 8 other US sites
- Eligibility basics
- Ages 18–75
- RecruitingPhase 2
A Single Dose of BRTX 100 for Patients With Chronic Lumbar Disc Disease (cLDD)
BioRestorative Therapies
- Location
- Santa Monica, CA + 13 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
Clinical Trial to Compare the Efficacy of Celiprolol to Placebo in Patients With Vascular Ehlers-Danlos Syndrome
Acer Therapeutics Inc.
- Location
- Culver City, CA
- Eligibility basics
- Ages 15–64
- RecruitingPhase 4
A Study of CREXONT (Carbidopa and Levodopa) Extended-Release Capsules in Participants With Parkinson's Disease
Impax Laboratories, LLC
- Location
- Aliso Viejo, CA + 22 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 3
A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis
Sumitomo Pharma Switzerland GmbH
- Location
- Burbank, CA + 101 other US sites
- Eligibility basics
- Ages 18–50 · Women only
- RecruitingPhase 3
Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults
SK Life Science, Inc.
- Location
- Palo Alto, CA + 6 other US sites
- Eligibility basics
- Ages 4–55
- RecruitingPhase 2
A Study to Evaluate the Safety and Efficacy of NEXAGON® (Lufepirsen Ophthalmic Gel) in Subjects With PCED
Glaukos Corporation
- Location
- Petaluma, CA + 19 other US sites
- Eligibility basics
- Ages 2+
- RecruitingPhase 2
Study With Phage for CF Subjects With Pseudomonas Lung Infection
BiomX Ltd
- Location
- San Francisco, CA + 8 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
MiGo Tracker Remote Monitoring of Home Exercise After Stroke
Flint Rehabilitation Devices, LLC
- Location
- Downey, CA
- Eligibility basics
- Ages 18+
- RecruitingPhase 1/Phase 2
MSC EVs in Dystrophic Epidermolysis Bullosa
Aegle Therapeutics
- Location
- Los Angeles, CA + 2 other US sites
- Eligibility basics
- Ages 6 mo+
- RecruitingPhase 3
Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Esophagus
GIE Medical
- Location
- Irvine, CA + 32 other US sites
- Eligibility basics
- Ages 22+
- RecruitingPhase 3
Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Bowel
GIE Medical
- Location
- Irvine, CA + 30 other US sites
- Eligibility basics
- Ages 22+
- RecruitingPhase 1
Evaluating the Effect Of Rifaximin on the Gut Microbiota and Metabolome in SIBO Using CapScan®
Envivo Bio Inc
- Location
- Mountain View, CA
- Eligibility basics
- Ages 18–80
- Recruiting
A Single-arm, Pivotal Study to Evaluate Acute Device and Technical Success of the CGuard Prime Carotid Stent System When Used in Conjunction to the ENROUTE Transcarotid Neuroprotection System in Patients Undergoing…
InspireMD
- Location
- Sacramento, CA + 7 other US sites
- Eligibility basics
- Ages 18–79