Location · California
Clinical trials recruiting in California
1900 recruiting studies have at least one site in California; 700 accept healthy volunteers. Studies that need a specific condition are included too, so check each listing.
Want the research companies that run paid Phase 1 studies for healthy volunteers? Paid clinical trial companies in California.
1,900 recruiting studiesSource: ClinicalTrials.gov, refreshed October 27, 2026How we list studies
More recruiting studies (pay not posted)
- RecruitingPhase 2
Study to Evaluate the Efficacy, Safety, and Tolerability of Efzofitimod in Patients With Systemic Sclerosis (SSc)-Related Interstitial Lung Disease (ILD) (SSc-ILD)
aTyr Pharma, Inc.
- Location
- Los Angeles, CA + 12 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Behavioral Treatment of Insomnia in Active-Duty Service Members With Traumatic Brain Injury
Noctem, LLC
- Location
- San Diego, CA
- Eligibility basics
- Ages 18+
- Recruiting
Clinical Protocol CERN Feasibility Study
Cern Corporation
- Location
- Irvine, CA + 2 other US sites
- Eligibility basics
- Ages 18+ · Women only
- RecruitingPhase 1
Study of APG-2575 as a Single Agent or in Combination With Other Therapeutic Agents for CLL/SLL
Ascentage Pharma Group Inc.
- Location
- Duarte, CA + 6 other US sites
- Eligibility basics
- Ages 18–85
- RecruitingPhase 3
InfasurfAero™ Versus Sham Treatment in Preterm Newborns With RDS
ONY
- Location
- San Diego, CA + 9 other US sites
- Eligibility basics
- Ages 7 mo–8 mo
- RecruitingPhase 2
Efficacy and Safety Study of Narsoplimab in Pediatric Patients With High-Risk Hematopoietic Stem Cell Transplant TMA
Omeros Corporation
- Location
- San Diego, CA + 2 other US sites
- Eligibility basics
- Ages 1 mo–17
- Recruiting
An Early Feasibility Study of the HighLife 28mm Trans-Septal Transcatheter Mitral Valve Replacement System
HighLife SAS
- Location
- Los Angeles, CA + 7 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Surgical Evaluation for Upper Extremity Lymphedema (BioBridge)
Fibralign Corporation
- Location
- Stanford, CA
- Eligibility basics
- Ages 18–75
- Recruiting
Innoventric Trillium™ Stent Graft Early Feasibility Study (EFS)
Innoventric LTD
- Location
- Thousand Oaks, CA + 8 other US sites
- Eligibility basics
- Ages 18–85
- Recruiting
VenusP-Valve Pivotal Study (PROTEUS STUDY)
Venus MedTech (HangZhou) Inc.
- Location
- Irvine, CA
- Eligibility basics
- Ages 12+
- Recruiting
MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions
Concept Medical Inc.
- Location
- Los Angeles, CA + 23 other US sites
- Eligibility basics
- Ages 18–110
- Recruiting
Freedom-1 Study for Chronic Knee Pain
Curonix LLC
- Location
- Placentia, CA + 12 other US sites
- Eligibility basics
- Ages 18+
- Recruiting
Rising Tide - Amniotic Tissue(s) Treatments for Chronic Diabetic Foot Ulcers
Tides Medical
- Location
- Fresno, CA + 8 other US sites
- Eligibility basics
- Ages 18+
- RecruitingPhase 1
Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC
Tenaya Therapeutics
- Location
- San Francisco, CA + 6 other US sites
- Eligibility basics
- Ages 18–65
- Recruiting
Augmented Reality BCI Longitudinal Study for Persons With Late Stage ALS
Cognixion
- Location
- Santa Barbara, CA
- Eligibility basics
- Ages 18+
- Recruiting
Dehydrated Human Amnion Membrane and Standard of Care Versus Standard of Care Alone in Nonhealing Diabetic Foot Ulcers
Axolotl Biologix
- Location
- Thousand Oaks, CA
- Eligibility basics
- Ages 18+
- RecruitingPhase 4
Qudexy XR for the Prevention of Migraine in Children 6 to 11 Years Old
Upsher-Smith Laboratories
- Location
- La Jolla, CA + 5 other US sites
- Eligibility basics
- Ages 6–11
- Recruiting
Evaluation of Safety and Effectiveness of Primary Hybrid Construct of Mobi-C and ACDF in the Treatment of Two-level Symptomatic Degenerative Disc Disease in the Cervical Spine.
Highridge Medical
- Location
- Sacramento, CA + 1 other US site
- Eligibility basics
- Ages 22–69
- RecruitingPhase 2
A Study to Assess Molecular Changes in Adult Participants With Moderate to Severe Hidradenitis Suppurativa or With Moderate to Severe Atopic Dermatitis Receiving Subcutaneous Injections of Lutikizumab
AbbVie
- Location
- Sacramento, CA + 1 other US site
- Eligibility basics
- Ages 18–75
- RecruitingPhase 4
A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
Axsome Therapeutics, Inc.
- Location
- Bellflower, CA + 36 other US sites
- Eligibility basics
- Ages 18–65
- Recruiting
EMAGINE 2.0 - Electromagnetic Field Ischemic Stroke - Novel Subacute Treatment
BrainQ Technologies Ltd.
- Location
- Downey, CA + 6 other US sites
- Eligibility basics
- Ages 22–80
- RecruitingPhase 2
A Study of NST-6179 in Subjects With Intestinal Failure-Associated Liver Disease (IFALD).
NorthSea Therapeutics B.V.
- Location
- San Francisco, CA + 11 other US sites
- Eligibility basics
- Ages 16+
- Recruiting
A Clinical Trial to Assess the Efficacy and Tolerance of a Berberine-based Nutraceutical Formula to Aid Blood Sugar Regulation and Metabolism
Ultimate International, Inc.
- Location
- Santa Monica, CA
- Eligibility basics
- Ages 18–70
- Recruiting
Telerehabilitation Early After Stroke
TRCare, Inc.
- Location
- Fullerton, CA
- Eligibility basics
- Ages 18+